KEGG   PATHWAY: metd00630
Entry
metd00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Methylobacterium sp. DM1
Class
Metabolism; Carbohydrate metabolism
Pathway map
metd00630  Glyoxylate and dicarboxylate metabolism
metd00630

Module
metd_M00621  Glycine cleavage system [PATH:metd00630]
metd_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:metd00630]
Other DBs
GO: 0046487 0043648
Organism
Methylobacterium sp. DM1 [GN:metd]
Gene
C0214_14465  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
C0214_24440  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
C0214_09615  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
C0214_25675  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
C0214_14830  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
C0214_10370  succinate--CoA ligase subunit alpha [KO:K08692] [EC:6.2.1.9]
C0214_10365  ADP-forming succinate--CoA ligase subunit beta [KO:K14067] [EC:6.2.1.9]
C0214_18985  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C0214_17950  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C0214_18990  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
C0214_18865  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
C0214_01265  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
C0214_04620  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
C0214_01275  protein meaA [KO:K14447] [EC:5.4.99.63]
C0214_12585  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
C0214_21035  hypothetical protein [KO:K14449] [EC:4.2.1.148]
C0214_10380  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
C0214_21595  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
C0214_16595  acetyl/propionyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
C0214_01235  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
C0214_13380  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
C0214_26240  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
C0214_03935  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
C0214_26205  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
C0214_17485  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
C0214_01270  catalase [KO:K03781] [EC:1.11.1.6]
C0214_17785  catalase [KO:K03781] [EC:1.11.1.6]
C0214_25425  catalase [KO:K03781] [EC:1.11.1.6]
C0214_01835  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
C0214_10350  glycerate dehydrogenase [KO:K00018] [EC:1.1.1.29]
C0214_01225  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
C0214_12915  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
C0214_11650  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
C0214_23050  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
C0214_10345  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
C0214_13320  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
C0214_13325  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
C0214_17600  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C0214_03580  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
C0214_27050  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
C0214_03590  glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
C0214_15615  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C0214_09585  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C0214_22415  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C0214_03585  gcvH; glycine cleavage system protein GcvH [KO:K02437]
C0214_23060  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
C0214_06495  glycerate kinase [KO:K11529] [EC:2.7.1.165]
C0214_15390  glycerate kinase [KO:K11529] [EC:2.7.1.165]
C0214_25710  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
C0214_06490  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
C0214_11440  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
C0214_24295  peptidase [KO:K00126] [EC:1.17.1.9]
C0214_00730  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
C0214_24290  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
C0214_01670  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
C0214_00735  NADH-quinone oxidoreductase subunit F [KO:K22515] [EC:1.17.1.9]
C0214_01675  formate dehydrogenase [KO:K00124]
C0214_24285  formate dehydrogenase [KO:K00124]
C0214_01680  formate dehydrogenase subunit gamma [KO:K00127]
C0214_24280  formate dehydrogenase subunit gamma [KO:K00127]
C0214_18525  formamidase [KO:K01455] [EC:3.5.1.49]
C0214_26885  hypothetical protein [KO:K25305] [EC:3.5.1.56]
C0214_12095  AMP-dependent synthetase [KO:K22133] [EC:6.2.1.8]
C0214_05115  oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
metd00010  Glycolysis / Gluconeogenesis
metd00020  Citrate cycle (TCA cycle)
metd00030  Pentose phosphate pathway
metd00053  Ascorbate and aldarate metabolism
metd00071  Fatty acid degradation
metd00230  Purine metabolism
metd00250  Alanine, aspartate and glutamate metabolism
metd00260  Glycine, serine and threonine metabolism
metd00620  Pyruvate metabolism
metd00710  Carbon fixation by Calvin cycle
metd00750  Vitamin B6 metabolism
metd00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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