KEGG   PATHWAY: mmu00040
Entry
mmu00040                    Pathway                                
Name
Pentose and glucuronate interconversions - Mus musculus (house mouse)
Class
Metabolism; Carbohydrate metabolism
Pathway map
mmu00040  Pentose and glucuronate interconversions
mmu00040

Module
mmu_M00014  Glucuronate pathway (uronate pathway) [PATH:mmu00040]
mmu_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:mmu00040]
Organism
Mus musculus (house mouse) [GN:mmu]
Gene
100559  Ugt2b38; UDP glucuronosyltransferase 2 family, polypeptide B38 [KO:K00699] [EC:2.4.1.17]
100727  Ugt2b34; UDP glucuronosyltransferase 2 family, polypeptide B34 [KO:K00699] [EC:2.4.1.17]
102448  Xylb; xylulokinase homolog (H. influenzae) [KO:K00854] [EC:2.7.1.17]
110006  Gusb; glucuronidase, beta [KO:K01195] [EC:3.2.1.31]
112417  Ugt2b37; UDP glucuronosyltransferase 2 family, polypeptide B37 [KO:K00699] [EC:2.4.1.17]
11677  Akr1b1; aldo-keto reductase family 1 member B [KO:K00011] [EC:1.1.1.21]
11997  Akr1b7; aldo-keto reductase family 1, member B7 [KO:K00011] [EC:1.1.1.21]
14187  Akr1b8; aldo-keto reductase family 1, member B8 [KO:K00011] [EC:1.1.1.21]
16591  Kl; klotho [KO:K14756] [EC:3.2.1.31]
20322  Sord; sorbitol dehydrogenase [KO:K00008] [EC:1.1.1.14]
216558  Ugp2; UDP-glucose pyrophosphorylase 2 [KO:K00963] [EC:2.7.7.9]
22235  Ugdh; UDP-glucose dehydrogenase [KO:K00012] [EC:1.1.1.22]
22236  Ugt1a2; UDP glucuronosyltransferase 1 family, polypeptide A2 [KO:K00699] [EC:2.4.1.17]
22238  Ugt2b5; UDP glucuronosyltransferase 2 family, polypeptide B5 [KO:K00699] [EC:2.4.1.17]
231396  Ugt2b36; UDP glucuronosyltransferase 2 family, polypeptide B36 [KO:K00699] [EC:2.4.1.17]
243085  Ugt2b35; UDP glucuronosyltransferase 2 family, polypeptide B35 [KO:K00699] [EC:2.4.1.17]
394430  Ugt1a10; UDP glycosyltransferase 1 family, polypeptide A10 [KO:K00699] [EC:2.4.1.17]
394432  Ugt1a7c; UDP glucuronosyltransferase 1 family, polypeptide A7C [KO:K00699] [EC:2.4.1.17]
394433  Ugt1a5; UDP glucuronosyltransferase 1 family, polypeptide A5 [KO:K00699] [EC:2.4.1.17]
394434  Ugt1a9; UDP glucuronosyltransferase 1 family, polypeptide A9 [KO:K00699] [EC:2.4.1.17]
394435  Ugt1a6b; UDP glucuronosyltransferase 1 family, polypeptide A6B [KO:K00699] [EC:2.4.1.17]
394436  Ugt1a1; UDP glucuronosyltransferase 1 family, polypeptide A1 [KO:K00699] [EC:2.4.1.17]
552899  Ugt2a2; UDP glucuronosyltransferase 2 family, polypeptide A2 [KO:K00699] [EC:2.4.1.17]
58810  Akr1a1; aldo-keto reductase family 1, member A1 [KO:K00002] [EC:1.1.1.2]
613123  Ugt1a8; UDP glucuronosyltransferase 1 family, polypeptide A8 [KO:K00699] [EC:2.4.1.17]
66646  Rpe; ribulose-5-phosphate-3-epimerase [KO:K01783] [EC:5.1.3.1]
67861  Akr1b10; aldo-keto reductase family 1, member B10 [KO:K00011] [EC:1.1.1.21]
67880  Dcxr; dicarbonyl L-xylulose reductase [KO:K03331] [EC:1.1.1.10]
68631  Cryl1; crystallin, lambda 1 [KO:K13247] [EC:1.1.1.45]
71755  Dhdh; dihydrodiol dehydrogenase [KO:K00078] [EC:1.3.1.20 1.1.1.179]
71773  Ugt2b1; UDP glucuronosyltransferase 2 family, polypeptide B1 [KO:K00699] [EC:2.4.1.17]
72094  Ugt2a3; UDP glucuronosyltransferase 2 family, polypeptide A3 [KO:K00699] [EC:2.4.1.17]
75578  Fggy; FGGY carbohydrate kinase domain containing [KO:K00875] [EC:2.7.1.47]
75847  Crppa; CDP-L-ribitol pyrophosphorylase A [KO:K21031] [EC:2.7.7.40]
94215  Ugt2a1; UDP glucuronosyltransferase 2 family, polypeptide A1 [KO:K00699] [EC:2.4.1.17]
94284  Ugt1a6a; UDP glucuronosyltransferase 1 family, polypeptide A6A [KO:K00699] [EC:2.4.1.17]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00167  UDP-glucuronate
C00181  D-Xylose
C00191  D-Glucuronate
C00199  D-Ribulose 5-phosphate
C00204  2-Dehydro-3-deoxy-D-gluconate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00266  Glycolaldehyde
C00309  D-Ribulose
C00310  D-Xylulose
C00312  L-Xylulose
C00333  D-Galacturonate
C00379  Xylitol
C00433  2,5-Dioxopentanoate
C00470  Pectate
C00474  Ribitol
C00476  D-Lyxose
C00502  D-Xylonate
C00508  L-Ribulose
C00514  D-Mannonate
C00532  L-Arabitol
C00558  D-Tagaturonate
C00618  3-Dehydro-L-gulonate
C00714  Pectin
C00789  CDP-ribitol
C00800  L-Gulonate
C00817  D-Altronate
C00905  D-Fructuronate
C01068  D-Ribitol 5-phosphate
C01101  L-Ribulose 5-phosphate
C01508  L-Lyxose
C01904  D-Arabitol
C02266  D-Xylonolactone
C02273  Digalacturonate
C02426  L-Glyceraldehyde
C02753  D-Xylono-1,4-lactone
C03033  beta-D-Glucuronoside
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C04053  5-Dehydro-4-deoxy-D-glucuronate
C04349  (4S)-4,6-Dihydroxy-2,5-dioxohexanoate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C06118  4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate
C06441  L-Xylulose 1-phosphate
C14899  3-Dehydro-L-gulonate 6-phosphate
C15930  L-Galactonate
C20680  2-Dehydro-3-deoxy-L-galactonate
C22337  D-Ribulose 1-phosphate
C22712  4-Deoxy-L-threo-hex-4-enopyranuronate
Reference
  Authors
Yew WS, Gerlt JA.
  Title
Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.
  Journal
J Bacteriol 184:302-6 (2002)
DOI:10.1128/JB.184.1.302-306.2002
Reference
  Authors
Yew WS, Akana J, Wise EL, Rayment I, Gerlt JA
  Title
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
  Journal
Biochemistry 44:1807-15 (2005)
DOI:10.1021/bi047815v
Reference
  Authors
Yasueda H, Kawahara Y, Sugimoto S.
  Title
Bacillus subtilis yckG and yckF encode two key enzymes of the ribulose monophosphate pathway used by methylotrophs, and yckH is required for their expression.
  Journal
J Bacteriol 181:7154-60 (1999)
DOI:10.1128/JB.181.23.7154-7160.1999
Reference
  Authors
Ibanez E, Gimenez R, Pedraza T, Baldoma L, Aguilar J, Badia J
  Title
Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose.
  Journal
J Bacteriol 182:4625-7 (2000)
DOI:10.1128/JB.182.16.4625-4627.2000
Reference
  Authors
Orita I, Yurimoto H, Hirai R, Kawarabayasi Y, Sakai Y, Kato N
  Title
The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway.
  Journal
J Bacteriol 187:3636-42 (2005)
DOI:10.1128/JB.187.11.3636-3642.2005
Related
pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00020  Citrate cycle (TCA cycle)
mmu00030  Pentose phosphate pathway
mmu00052  Galactose metabolism
mmu00053  Ascorbate and aldarate metabolism
mmu00520  Amino sugar and nucleotide sugar metabolism
mmu00561  Glycerolipid metabolism
mmu00562  Inositol phosphate metabolism
mmu00740  Riboflavin metabolism
KO pathway
ko00040   

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