KEGG   PATHWAY: mmu00562
Entry
mmu00562                    Pathway                                
Name
Inositol phosphate metabolism - Mus musculus (house mouse)
Class
Metabolism; Carbohydrate metabolism
Pathway map
mmu00562  Inositol phosphate metabolism
mmu00562

Module
mmu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:mmu00562]
mmu_M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:mmu00562]
mmu_M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:mmu00562]
Other DBs
GO: 0006020
Organism
Mus musculus (house mouse) [GN:mmu]
Gene
101490  Inpp5f; inositol polyphosphate-5-phosphatase F [KO:K21798] [EC:3.1.3.-]
103199  Fig4; FIG4 phosphoinositide 5-phosphatase [KO:K22913] [EC:3.1.3.-]
104015  Synj1; synaptojanin 1 [KO:K20279] [EC:3.1.3.36]
104776  Aldh6a1; aldehyde dehydrogenase family 6, subfamily A1 [KO:K00140] [EC:1.2.1.18 1.2.1.27]
107650  Pi4kb; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
108083  Pip4k2b; phosphatidylinositol-5-phosphate 4-kinase, type II, beta [KO:K00920] [EC:2.7.1.149]
114663  Impa2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
114875  Plcz1; phospholipase C, zeta 1 [KO:K05861] [EC:3.1.4.11]
117150  Pip4k2c; phosphatidylinositol-5-phosphate 4-kinase, type II, gamma [KO:K00920] [EC:2.7.1.149]
16329  Inpp1; inositol polyphosphate-1-phosphatase [KO:K01107] [EC:3.1.3.57]
16330  Inpp5b; inositol polyphosphate-5-phosphatase B [KO:K01099] [EC:3.1.3.36]
16331  Inpp5d; inositol polyphosphate-5-phosphatase D [KO:K03084] [EC:3.1.3.86]
16332  Inppl1; inositol polyphosphate phosphatase-like 1 [KO:K15909] [EC:3.1.3.86]
170749  Mtmr4; myotubularin related protein 4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
170835  Inpp5j; inositol polyphosphate 5-phosphatase J [KO:K24222]
17330  Minpp1; multiple inositol polyphosphate histidine phosphatase 1 [KO:K03103] [EC:3.1.3.62 3.1.3.80]
17772  Mtm1; X-linked myotubular myopathy gene 1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
18704  Pik3c2a; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [KO:K00923] [EC:2.7.1.154]
18705  Pik3c2g; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [KO:K00923] [EC:2.7.1.154]
18706  Pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153]
18707  Pik3cd; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [KO:K00922] [EC:2.7.1.153]
18711  Pikfyve; phosphoinositide kinase, FYVE type zinc finger containing [KO:K00921] [EC:2.7.1.150]
18717  Pip5k1c; phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma [KO:K00889] [EC:2.7.1.68]
18718  Pip4k2a; phosphatidylinositol-5-phosphate 4-kinase, type II, alpha [KO:K00920] [EC:2.7.1.149]
18719  Pip5k1b; phosphatidylinositol-4-phosphate 5-kinase, type 1 beta [KO:K00889] [EC:2.7.1.68]
18720  Pip5k1a; phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha [KO:K00889] [EC:2.7.1.68]
18795  Plcb1; phospholipase C, beta 1 [KO:K05858] [EC:3.1.4.11]
18796  Plcb2; phospholipase C, beta 2 [KO:K05858] [EC:3.1.4.11]
18797  Plcb3; phospholipase C, beta 3 [KO:K05858] [EC:3.1.4.11]
18798  Plcb4; phospholipase C, beta 4 [KO:K05858] [EC:3.1.4.11]
18799  Plcd1; phospholipase C, delta 1 [KO:K05857] [EC:3.1.4.11]
18802  Plcd4; phospholipase C, delta 4 [KO:K05857] [EC:3.1.4.11]
18803  Plcg1; phospholipase C, gamma 1 [KO:K01116] [EC:3.1.4.11]
19062  Inpp5k; inositol polyphosphate 5-phosphatase K [KO:K24222]
19211  Pten; phosphatase and tensin homolog [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
20975  Synj2; synaptojanin 2 [KO:K20279] [EC:3.1.3.36]
212111  Inpp5a; inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
217837  Itpk1; inositol 1,3,4-triphosphate 5/6 kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
219135  Mtmr6; myotubularin related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
21991  Tpi1; triosephosphate isomerase 1 [KO:K01803] [EC:5.3.1.1]
224020  Pi4ka; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
225326  Pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
227733  Pip5kl1; phosphatidylinositol-4-phosphate 5-kinase-like 1 [KO:K13712] [EC:2.7.1.68]
228550  Itpka; inositol 1,4,5-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
233011  Itpkc; inositol 1,4,5-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
234515  Inpp4b; inositol polyphosphate-4-phosphatase, type II [KO:K01109] [EC:3.1.3.66]
234779  Plcg2; phospholipase C, gamma 2 [KO:K05859] [EC:3.1.4.11]
240752  Pik3c2b; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [KO:K00923] [EC:2.7.1.154]
269180  Inpp4a; inositol polyphosphate-4-phosphatase, type I [KO:K01109] [EC:3.1.3.66]
269437  Plch1; phospholipase C, eta 1 [KO:K19006] [EC:3.1.4.11]
269615  Plch2; phospholipase C, eta 2 [KO:K19006] [EC:3.1.4.11]
30955  Pik3cg; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [KO:K21289] [EC:2.7.1.153]
320404  Itpkb; inositol 1,4,5-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
320634  Ocrl; OCRL, inositol polyphosphate-5-phosphatase [KO:K01099] [EC:3.1.3.36]
52858  Cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
53332  Mtmr1; myotubularin related protein 1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
54384  Mtmr7; myotubularin related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
55980  Impa1; inositol (myo)-1(or 4)-monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
56727  Miox; myo-inositol oxygenase [KO:K00469] [EC:1.13.99.1]
64436  Inpp5e; inositol polyphosphate-5-phosphatase E [KO:K20278] [EC:3.1.3.36]
67073  Pi4k2b; phosphatidylinositol 4-kinase type 2 beta [KO:K13711] [EC:2.7.1.67]
69718  Ipmk; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
71780  Isyna1; myo-inositol 1-phosphate synthase A1 [KO:K01858] [EC:5.5.1.4]
72469  Plcd3; phospholipase C, delta 3 [KO:K05857] [EC:3.1.4.11]
74055  Plce1; phospholipase C, epsilon 1 [KO:K05860] [EC:3.1.4.11]
74302  Mtmr3; myotubularin related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
74769  Pik3cb; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [KO:K00922] [EC:2.7.1.153]
75678  Ippk; inositol 1,3,4,5,6-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
77116  Mtmr2; myotubularin related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
83493  Sacm1l; SAC1 suppressor of actin mutations 1-like (yeast) [KO:K21797] [EC:3.1.3.-]
84095  Pi4k2a; phosphatidylinositol 4-kinase type 2 alpha [KO:K13711] [EC:2.7.1.67]
97287  Mtmr14; myotubularin related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
Compound
C00024  Acetyl-CoA
C00092  D-Glucose 6-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00137  myo-Inositol
C00191  D-Glucuronate
C00222  3-Oxopropanoate
C00558  D-Tagaturonate
C00641  1,2-Diacyl-sn-glycerol
C00691  2,4,6/3,5-Pentahydroxycyclohexanone
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C03659  D-Bornesitol
C03660  L-Bornesitol
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04287  3D-3,5/4-Trihydroxycyclohexane-1,2-dione
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  Inositol 1,2,3,5,6-pentakisphosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C06153  scyllo-Inositol
C06892  2-Deoxy-5-keto-D-gluconic acid
C06893  2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  5-Deoxy-D-glucuronate
C19794  CDP-1L-myo-inositol
C19799  Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  1D-chiro-Inositol
C20251  1-Keto-D-chiro-inositol
C21643  3-Dehydro-scyllo-inosose
C21644  5-Dehydro-L-gluconate
Reference
PMID:14993306
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
DOI:10.1099/mic.0.26768-0
Reference
PMID:18310071
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)
DOI:10.1074/jbc.M708043200
Related
pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00020  Citrate cycle (TCA cycle)
mmu00040  Pentose and glucuronate interconversions
mmu00564  Glycerophospholipid metabolism
KO pathway
ko00562   

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