KEGG   PATHWAY: mthn00630
Entry
mthn00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium thermoresistibile
Class
Metabolism; Carbohydrate metabolism
Pathway map
mthn00630  Glyoxylate and dicarboxylate metabolism
mthn00630

Module
mthn_M00621  Glycine cleavage system [PATH:mthn00630]
mthn_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mthn00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium thermoresistibile [GN:mthn]
Gene
4412656_00256  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
4412656_00259  fadI; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
4412656_00401  [KO:K00626] [EC:2.3.1.9]
4412656_00403  [KO:K00626] [EC:2.3.1.9]
4412656_00559  lpd; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
4412656_00565  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
4412656_00700  gph; HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
4412656_01168  accC_2; carbamoyl-phosphate synthase subunit L [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
4412656_01172  [KO:K27095]
4412656_01173  accD5_1; carboxyl transferase [KO:K27094]
4412656_01414  thlA_1; acetyl-CoA acetyl transferase [KO:K00626] [EC:2.3.1.9]
4412656_01426  phbA; acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
4412656_01784  accD6; propionyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
4412656_01798  [KO:K01091] [EC:3.1.3.18]
4412656_01811  glnA_1; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
4412656_01817  glnA_2; L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
4412656_01827  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
4412656_01833  glxK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
4412656_01976  mutA; methylmalonyl-CoA mutase, beta subunit [KO:K01847] [EC:5.4.99.2]
4412656_01977  mutB; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
4412656_02243  gcvH; glycine cleavage system protein H [KO:K02437]
4412656_02248  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
4412656_02251  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
4412656_02282  [KO:K00626] [EC:2.3.1.9]
4412656_02358  icl; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
4412656_02442  acnA; aconitate hydratase [KO:K27802]
4412656_03009  pcaF_1; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
4412656_03112  thlA_2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
4412656_03121  scpA_2; cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
4412656_03122  scpA_3; methylmalonyl CoA mutase [KO:K01848] [EC:5.4.99.2]
4412656_03154  [KO:K00626] [EC:2.3.1.9]
4412656_03155  [KO:K05606] [EC:5.1.99.1]
4412656_03199  pcaF_2; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
4412656_03246  pcaF_3; thiolase [KO:K00626] [EC:2.3.1.9]
4412656_03320  [KO:K00104] [EC:1.1.99.14]
4412656_03355  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
4412656_03468  pcaF_4; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
4412656_03500  [KO:K00626] [EC:2.3.1.9]
4412656_03567  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
4412656_03587  thlA_3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
4412656_03772  [KO:K00626] [EC:2.3.1.9]
4412656_03858  gltA2; citrate synthase I, hexameric type [KO:K01647] [EC:2.3.3.1]
4412656_03861  citA; citrate synthase [KO:K01647] [EC:2.3.3.1]
4412656_03895  fadA_4; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
4412656_04040  [KO:K00626] [EC:2.3.1.9]
4412656_04267  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
4412656_04312  katA; catalase [KO:K03781] [EC:1.11.1.6]
4412656_04451  katE; catalase [KO:K03781] [EC:1.11.1.6]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mthn00010  Glycolysis / Gluconeogenesis
mthn00020  Citrate cycle (TCA cycle)
mthn00030  Pentose phosphate pathway
mthn00053  Ascorbate and aldarate metabolism
mthn00071  Fatty acid degradation
mthn00230  Purine metabolism
mthn00250  Alanine, aspartate and glutamate metabolism
mthn00260  Glycine, serine and threonine metabolism
mthn00270  Cysteine and methionine metabolism
mthn00620  Pyruvate metabolism
mthn00710  Carbon fixation by Calvin cycle
mthn00750  Vitamin B6 metabolism
mthn00910  Nitrogen metabolism
KO pathway
ko00630   

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