KEGG   PATHWAY: aab00630
Entry
aab00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Amycolatopsis albispora
Class
Metabolism; Carbohydrate metabolism
Pathway map
aab00630  Glyoxylate and dicarboxylate metabolism
aab00630

Module
aab_M00012  Glyoxylate cycle [PATH:aab00630]
aab_M00621  Glycine cleavage system [PATH:aab00630]
aab_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:aab00630]
Other DBs
GO: 0046487 0043648
Organism
Amycolatopsis albispora [GN:aab]
Gene
A4R43_20220  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
A4R43_11280  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
A4R43_27085  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
A4R43_05650  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
A4R43_18630  malate synthase A [KO:K01638] [EC:2.3.3.9]
A4R43_20215  malate synthase A [KO:K01638] [EC:2.3.3.9]
A4R43_09020  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
A4R43_25535  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
A4R43_25635  citrate synthase [KO:K01647] [EC:2.3.3.1]
A4R43_02065  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
A4R43_03280  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
A4R43_11120  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
A4R43_23745  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
A4R43_15915  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
A4R43_15930  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
A4R43_15980  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
A4R43_07105  enoyl-CoA hydratase [KO:K00626] [EC:2.3.1.9]
A4R43_20555  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
A4R43_22855  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
A4R43_31085  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
A4R43_20560  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
A4R43_22310  protein meaA [KO:K14447] [EC:5.4.99.63]
A4R43_28985  aldolase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
A4R43_35355  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
A4R43_35050  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
A4R43_35135  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
A4R43_35130  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit [KO:K27095]
A4R43_05600  propionyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
A4R43_37755  propionyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
A4R43_34965  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
A4R43_34970  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
A4R43_03730  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
A4R43_10015  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
A4R43_31575  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
A4R43_22820  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
A4R43_05960  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
A4R43_27305  catalase [KO:K03781] [EC:1.11.1.6]
A4R43_08010  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
A4R43_19400  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
A4R43_25845  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
A4R43_18170  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
A4R43_03780  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
A4R43_10515  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
A4R43_03455  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
A4R43_22105  type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
A4R43_22150  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
A4R43_13600  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
A4R43_13770  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
A4R43_19180  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
A4R43_26895  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
A4R43_19145  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
A4R43_09650  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
A4R43_19160  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
A4R43_19155  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
A4R43_18940  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
A4R43_17820  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
A4R43_11260  glycine cleavage system protein H [KO:K02437]
A4R43_19150  glycine cleavage system protein H [KO:K02437]
A4R43_05990  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
A4R43_03475  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
A4R43_06000  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
A4R43_03465  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
A4R43_33785  sugar phosphate isomerase [KO:K01816] [EC:5.3.1.22]
A4R43_05770  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
A4R43_05995  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
A4R43_03470  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
A4R43_13230  glycerate kinase [KO:K00865] [EC:2.7.1.165]
A4R43_05985  glycerate kinase [KO:K00865] [EC:2.7.1.165]
A4R43_19405  glycerate kinase [KO:K00865] [EC:2.7.1.165]
A4R43_22800  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
A4R43_37925  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
A4R43_16950  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
A4R43_23050  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
A4R43_05850  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
A4R43_05855  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
A4R43_05860  formate dehydrogenase [KO:K00124]
A4R43_05865  NADH dehydrogenase [KO:K00127]
A4R43_09610  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
A4R43_32715  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
aab00010  Glycolysis / Gluconeogenesis
aab00020  Citrate cycle (TCA cycle)
aab00030  Pentose phosphate pathway
aab00053  Ascorbate and aldarate metabolism
aab00071  Fatty acid degradation
aab00230  Purine metabolism
aab00250  Alanine, aspartate and glutamate metabolism
aab00260  Glycine, serine and threonine metabolism
aab00620  Pyruvate metabolism
aab00710  Carbon fixation by Calvin cycle
aab00750  Vitamin B6 metabolism
aab00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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