KEGG PATHWAY: bced00630

KEGG

PATHWAY: bced00630

Entry

bced00630                   Pathway

Name

Glyoxylate and dicarboxylate metabolism - Burkholderia cepacia DDS 7H-2

Class

Metabolism; Carbohydrate metabolism

Pathway map

Glyoxylate and dicarboxylate metabolism

Module

Glyoxylate cycle [PATH:bced00630]

Glycine cleavage system [PATH:bced00630]

Other DBs

GO:	0046487 0043648

Organism

Burkholderia cepacia DDS 7H-2 [GN:bced]

Gene

aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]

isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]

AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]

AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]

AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]

acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]

acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]

AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]

glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]

aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]

mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]

gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]

citrate synthase family protein [KO:K01647] [EC:2.3.3.1]

2-methylcitrate synthase/citrate synthase II family protein [KO:K01659] [EC:2.3.3.5]

acnA; aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]

acnB; aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]

acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]

acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]

acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]

acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]

acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]

acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]

acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]

acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]

phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]

phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]

phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]

maoC like domain protein [KO:K17865] [EC:4.2.1.55]

FAD binding domain protein [KO:K00104] [EC:1.1.99.14]

FAD binding domain protein [KO:K00104] [EC:1.1.99.14]

FAD binding domain protein [KO:K11472] [EC:1.1.99.14]

FAD binding domain protein [KO:K11472] [EC:1.1.99.14]

4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]

4Fe-4S dicluster domain protein [KO:K11473] [EC:1.1.99.14]

catalase family protein [KO:K03781] [EC:1.11.1.6]

catalase family protein [KO:K03781] [EC:1.11.1.6]

catalase family protein [KO:K03781] [EC:1.11.1.6]

catalase family protein [KO:K03781] [EC:1.11.1.6]

D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]

ghrA; glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]

ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]

D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]

D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00018] [EC:1.1.1.29]

gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]

HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]

haloacid dehalogenase-like hydrolase family protein [KO:K01091] [EC:3.1.3.18]

HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]

glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]

glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]

glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]

glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]

glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]

beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]

gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]

gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]

lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]

lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]

lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]

gcvH; glycine cleavage system H protein [KO:K02437]

gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]

hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]

2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]

glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]

tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]

tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]

tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]

eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]

oxdD; oxalate decarboxylase oxdD [KO:K01569] [EC:4.1.1.2]

fdh; NAD-dependent formate dehydrogenase [KO:K00122] [EC:1.17.1.9]

NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]

formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]

molybdopterin oxidoreductase Fe4S4 domain protein [KO:K00123] [EC:1.17.1.9]

formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]

fdxH; formate dehydrogenase, beta subunit [KO:K00124]

NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]

formate dehydrogenase, gamma subunit [KO:K00127]

thioredoxin-like [2Fe-2S] ferredoxin family protein [KO:K00127]

alpha/beta hydrolase fold family protein [KO:K01432] [EC:3.5.1.9]

kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]

purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]

purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]

hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]

Compound

Oxygen

CO2

Ammonia

Pyruvate

Acetyl-CoA

L-Glutamate

2-Oxoglutarate

Hydrogen peroxide

Acetate

Oxaloacetate

Glycine

Succinate

Glyoxylate

Formate

L-Glutamine

L-Serine

Succinyl-CoA

Propanoyl-CoA

Glycerone phosphate

Butanoyl-CoA

(S)-Malate

Citrate

Glycolate

Hydroxypyruvate

3-Phospho-D-glycerate

Oxalate

D-Glycerate

Glycolaldehyde

Isocitrate

Oxalyl-CoA

Acetoacetyl-CoA

cis-Aconitate

meso-Tartaric acid

2-Phospho-D-glycerate

(S)-Methylmalonyl-CoA

Formyl-CoA

Crotonoyl-CoA

Pentanoyl-CoA

(R,R)-Tartaric acid

Dihydroxyfumarate

2-Phosphoglycolate

4-Hydroxy-2-oxoglutarate

2-Hydroxy-3-oxopropanoate

D-Ribulose 1,5-bisphosphate

(R)-Methylmalonyl-CoA

Ethylene glycol

Mesaconate

3-Ethylmalate

3-Oxalomalate

3-Propylmalate

Formyl phosphate

2-Hydroxy-3-oxoadipate

2-Hydroxy-3-oxosuccinate

trans-2,3-Epoxysuccinate

(R)-3-Hydroxybutanoyl-CoA

L-threo-3-Methylaspartate

L-Malyl-CoA

L-erythro-3-Methylmalyl-CoA

2-Methylfumaryl-CoA

N-Formylderivatives

(2S)-Ethylmalonyl-CoA

(2S)-Methylsuccinyl-CoA

(2R)-Ethylmalonyl-CoA

D-Ribulose 1-phosphate

Reference

Authors

Njau RK, Herndon CA, Hawes JW.

Title

Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.

Journal

J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200

Reference

Authors

Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G

Title

Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.

Journal

J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07

Reference

Authors

Erb TJ, Retey J, Fuchs G, Alber BE

Title

Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.

Journal

J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200

Reference

Authors

Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM

Title

Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.

Journal

Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741

Reference

Authors

Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A

Title

Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.

Journal

Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910

Reference

Authors

Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA

Title

A methylaspartate cycle in haloarchaea.

Journal

Science 331:334-7 (2011)
DOI:10.1126/science.1196544

Reference

Authors

Serrano JA, Bonete MJ

Title

Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.

Journal

Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9

Related
pathway

Glycolysis / Gluconeogenesis

Citrate cycle (TCA cycle)

Pentose phosphate pathway

Ascorbate and aldarate metabolism

Fatty acid degradation

Purine metabolism

Alanine, aspartate and glutamate metabolism

Glycine, serine and threonine metabolism

Pyruvate metabolism

Carbon fixation by Calvin cycle

Vitamin B6 metabolism

Nitrogen metabolism

KO pathway

LinkDB

DBGET integrated database retrieval system