KEGG   PATHWAY: cabk00630
Entry
cabk00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Caballeronia sp. NK8
Class
Metabolism; Carbohydrate metabolism
Pathway map
cabk00630  Glyoxylate and dicarboxylate metabolism
cabk00630

Module
cabk_M00012  Glyoxylate cycle [PATH:cabk00630]
cabk_M00621  Glycine cleavage system [PATH:cabk00630]
Other DBs
GO: 0046487 0043648
Organism
Caballeronia sp. NK8 [GN:cabk]
Gene
NK8_11110  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
NK8_45720  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
NK8_10150  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
NK8_31640  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
NK8_11070  malate synthase A [KO:K01638] [EC:2.3.3.9]
NK8_61740  malate synthase G [KO:K01638] [EC:2.3.3.9]
NK8_30410  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NK8_30480  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
NK8_32360  helix-turn-helix domain-containing protein [KO:K01647] [EC:2.3.3.1]
NK8_68320  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
NK8_83790  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
NK8_30360  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
NK8_49160  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
NK8_14150  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NK8_15770  beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
NK8_15870  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NK8_16720  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NK8_30000  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NK8_44550  beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
NK8_64020  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
NK8_65630  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NK8_69010  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
NK8_84570  hypothetical protein [KO:K00626] [EC:2.3.1.9]
NK8_00910  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NK8_15860  3-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
NK8_65620  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
NK8_71610  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
NK8_03640  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
NK8_55540  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
NK8_03630  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
NK8_55530  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
NK8_03620  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
NK8_55520  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
NK8_03550  catalase [KO:K03781] [EC:1.11.1.6]
NK8_32140  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
NK8_76720  catalase [KO:K03781] [EC:1.11.1.6]
NK8_78720  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
NK8_00790  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
NK8_15360  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
NK8_20140  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
NK8_43550  D-2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
NK8_46630  D-2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
NK8_20050  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
NK8_24410  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
NK8_41520  form I ribulose bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
NK8_41500  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
NK8_60350  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
NK8_09700  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NK8_39140  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
NK8_54860  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
NK8_22880  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NK8_58910  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NK8_81150  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NK8_27440  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
NK8_27460  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
NK8_09860  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NK8_16800  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NK8_34770  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NK8_41130  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NK8_64840  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NK8_27450  gcvH; glycine cleavage system protein GcvH [KO:K02437]
NK8_13410  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
NK8_13400  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
NK8_13390  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
NK8_26570  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
NK8_70360  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
NK8_13900  glycerate kinase [KO:K00865] [EC:2.7.1.165]
NK8_51790  aldA; aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
NK8_46500  fumarate hydratase [KO:K03779] [EC:4.2.1.32]
NK8_78860  ttdA; L(+)-tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
NK8_46490  fumarate hydrolyase [KO:K03780] [EC:4.2.1.32]
NK8_78850  ttdB; L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
NK8_60070  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NK8_77920  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NK8_78690  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NK8_23170  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
NK8_45450  NAD-dependent formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
NK8_20970  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
NK8_20960  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
NK8_40040  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
NK8_20950  formate dehydrogenase [KO:K00124]
NK8_40030  fdxH; formate dehydrogenase subunit beta [KO:K00124]
NK8_20940  NAD(P)H-dependent oxidoreductase subunit E [KO:K00127]
NK8_40020  formate dehydrogenase subunit gamma [KO:K00127]
NK8_57590  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
NK8_22740  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
NK8_29750  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
NK8_02570  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
NK8_39680  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
NK8_32930  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
NK8_49230  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
NK8_31430  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
NK8_49220  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cabk00010  Glycolysis / Gluconeogenesis
cabk00020  Citrate cycle (TCA cycle)
cabk00030  Pentose phosphate pathway
cabk00053  Ascorbate and aldarate metabolism
cabk00071  Fatty acid degradation
cabk00230  Purine metabolism
cabk00250  Alanine, aspartate and glutamate metabolism
cabk00260  Glycine, serine and threonine metabolism
cabk00620  Pyruvate metabolism
cabk00710  Carbon fixation by Calvin cycle
cabk00750  Vitamin B6 metabolism
cabk00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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