KEGG   PATHWAY: cbw00630
Entry
cbw00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cupriavidus basilensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
cbw00630  Glyoxylate and dicarboxylate metabolism
cbw00630

Module
cbw_M00012  Glyoxylate cycle [PATH:cbw00630]
cbw_M00621  Glycine cleavage system [PATH:cbw00630]
Other DBs
GO: 0046487 0043648
Organism
Cupriavidus basilensis [GN:cbw]
Gene
RR42_s1037  Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
RR42_m2469  Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
RR42_m1282  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
RR42_m2146  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
RR42_s0838  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
RR42_s0395  Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
RR42_m2818  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
RR42_m2464  Malate synthase [KO:K01638] [EC:2.3.3.9]
RR42_m2937  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
RR42_m2114  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
RR42_m2930  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
RR42_s3234  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
RR42_m1876  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
RR42_s2428  Citrate synthase (si) [KO:K01647] [EC:2.3.3.1]
RR42_m2939  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
RR42_m2272  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
RR42_m2942  Aconitate hydratase or 2-methylisocitrate dehydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
RR42_s0560  Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
RR42_m2123  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s0721  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s1515  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s1087  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_m0176  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
RR42_m2234  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
RR42_s1586  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s0855  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s0906  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s2322  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s2328  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s0941  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s0956  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_m1540  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_m1546  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s1319  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_m2070  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s3249  3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s1335  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RR42_s1086  Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
RR42_m1541  Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
RR42_s1894  Glycolate dehydrogenase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
RR42_m3521  Glycolate dehydrogenase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
RR42_m3523  Glycolate dehydrogenase, FAD-binding subunit GlcE [KO:K11472] [EC:1.1.99.14]
RR42_s1892  Glycolate dehydrogenase, iron-sulfur subunit GlcF [KO:K11473] [EC:1.1.99.14]
RR42_m3524  Glycolate dehydrogenase, iron-sulfur subunit GlcF [KO:K11473] [EC:1.1.99.14]
RR42_m3537  Catalase [KO:K03781] [EC:1.11.1.6]
RR42_m0191  D-3-phosphoglycerate dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
RR42_s1373  D-3-phosphoglycerate dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
RR42_m2881  Glyoxylate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
RR42_m3724  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
RR42_m2872  Phosphoglycolate phosphatase-like, clustered with ribosomal large subunit pseudouridine synthase C [KO:K01091] [EC:3.1.3.18]
RR42_s2004  Serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
RR42_m3153  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RR42_m4086  Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) [KO:K00281] [EC:1.4.4.2]
RR42_m4083  Aminomethyltransferase (glycine cleavage system T protein) [KO:K00605] [EC:2.1.2.10]
RR42_s2849  Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
RR42_s1092  Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [KO:K00382] [EC:1.8.1.4]
RR42_m2619  Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase [KO:K00382] [EC:1.8.1.4]
RR42_m1492  Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [KO:K00382] [EC:1.8.1.4]
RR42_s0197  Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [KO:K00382] [EC:1.8.1.4]
RR42_m4084  Glycine cleavage system H protein [KO:K02437]
RR42_m4035  Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
RR42_m4036  Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
RR42_s0503  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
RR42_m4037  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
RR42_m3426  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
RR42_s0502  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
RR42_m4038  D-glycerate 2-kinase [KO:K11529] [EC:2.7.1.165]
RR42_s2712  D-glycerate 2-kinase [KO:K11529] [EC:2.7.1.165]
RR42_m0536  D-glycerate 2-kinase [KO:K11529] [EC:2.7.1.165]
RR42_m0449  Putative Tartrate dehydratase beta subunit [KO:K03780] [EC:4.2.1.32]
RR42_m0535  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RR42_s2715  Tartrate dehydrogenase or Tartrate decarboxylase or D-malic enzyme [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RR42_s1686  4-hydroxy-2-oxoglutarate aldolase or 2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RR42_m0776  NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
RR42_s2196  tungsten-containing formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
RR42_m0774  NAD-dependent formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
RR42_m3256  Formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
RR42_s2197  tungsten-containing formate dehydrogenase beta subunit [KO:K22515] [EC:1.17.1.9]
RR42_m0773  NAD-dependent formate dehydrogenase beta subunit [KO:K00124]
RR42_m3255  Formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
RR42_m0772  NAD-dependent formate dehydrogenase gamma subunit [KO:K00127]
RR42_m3253  Formate dehydrogenase O gamma subunit [KO:K00127]
RR42_m3427  hypothetical protein [KO:K01432] [EC:3.5.1.9]
RR42_m3130  Kynurenine formamidase, bacterial [KO:K07130] [EC:3.5.1.9]
RR42_m2802  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
RR42_m2506  Formamidase [KO:K01455] [EC:3.5.1.49]
RR42_m3439  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
RR42_s2207  Formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cbw00010  Glycolysis / Gluconeogenesis
cbw00020  Citrate cycle (TCA cycle)
cbw00030  Pentose phosphate pathway
cbw00053  Ascorbate and aldarate metabolism
cbw00071  Fatty acid degradation
cbw00230  Purine metabolism
cbw00250  Alanine, aspartate and glutamate metabolism
cbw00260  Glycine, serine and threonine metabolism
cbw00620  Pyruvate metabolism
cbw00710  Carbon fixation by Calvin cycle
cbw00750  Vitamin B6 metabolism
cbw00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system