KEGG   PATHWAY: cpl00230
Entry
cpl00230                    Pathway                                
Name
Purine metabolism - Corynebacterium pseudotuberculosis 3/99-5
Class
Metabolism; Nucleotide metabolism
Pathway map
cpl00230  Purine metabolism
cpl00230

Module
cpl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cpl00230]
cpl_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cpl00230]
cpl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cpl00230]
cpl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cpl00230]
cpl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cpl00230]
Other DBs
GO: 0006163 0042278
Organism
Corynebacterium pseudotuberculosis 3/99-5 [GN:cpl]
Gene
Cp3995_1736  pgm1; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
Cp3995_0716  prsA; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Cp3995_1771  purF; Amidophosphoribosyl transferase [KO:K00764] [EC:2.4.2.14]
Cp3995_1786  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Cp3995_0655  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Cp3995_1887  purT; Phosphoribosyl glycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
Cp3995_1776  purL; Phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
Cp3995_1778  purS; Phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
Cp3995_1777  purQ; Phosphoribosylformylglycinamidne synthase subunit I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Cp3995_1770  purM; Phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
Cp3995_0499  purK; Phosphoribosyl amino imidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
Cp3995_0500  purE; Phosphoribosyl amino imidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
Cp3995_1782  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Cp3995_1783  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Cp3995_0656  purH; Bifunctional purine biosynthesis protein purH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Cp3995_1193  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Cp3995_1542  N-acetyl glucosamine related protein [KO:K02566] [EC:3.1.3.5]
Cp3995_0162  deoD; Purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
Cp3995_1427  Uncharacterized protein yfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Cp3995_1823  iunH2; Inosine-uridine preferring nucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
Cp3995_1842  hpt; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Cp3995_0429  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Cp3995_0430  guaB2; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Cp3995_1630  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Cp3995_1698  Deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
Cp3995_0432  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
Cp3995_1103  Glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Cp3995_1514  Inosine 5-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
Cp3995_1149  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
Cp3995_1717  nrdE; Ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
Cp3995_1715  nrdF2; Ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
Cp3995_1774  nrdF; Ribonucleoside-diphosphate reductase beta chain 2 [KO:K00526] [EC:1.17.4.1]
Cp3995_0333  nrdD; Anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
Cp3995_1553  dgt; Deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
Cp3995_1192  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Cp3995_0729  gppA2; Ppx/GppA phosphatase family [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Cp3995_0264  gppA1; Ppx/GppA phosphatase family [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Cp3995_0229  cyaA; Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Cp3995_1899  purA; Adenylo succinate synthetase [KO:K01939] [EC:6.3.4.4]
Cp3995_0473  add; Adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Cp3995_0065  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Cp3995_0389  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Cp3995_1213  Hit (histidine triad) family protein [KO:K19710] [EC:2.7.7.53]
Cp3995_1973  ureC; Urease alpha subunit [KO:K01428] [EC:3.5.1.5]
Cp3995_1974  ureB; Urease beta subunit [KO:K01429] [EC:3.5.1.5]
Cp3995_1975  ureA; Urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cpl00030  Pentose phosphate pathway
cpl00220  Arginine biosynthesis
cpl00250  Alanine, aspartate and glutamate metabolism
cpl00260  Glycine, serine and threonine metabolism
cpl00340  Histidine metabolism
cpl00630  Glyoxylate and dicarboxylate metabolism
cpl00730  Thiamine metabolism
cpl00740  Riboflavin metabolism
cpl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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