Entry
Name
Arginine and proline metabolism - Dickeya aquatica
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
daq00330 Arginine and proline metabolism
Ortholog table
Module
Other DBs
Organism
Dickeya aquatica [GN:
daq ]
Gene
DAQ1742_04257 putA; Proline dehydrogenase (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase/PutA represses transcription of the put regulon [KO:K13821 ] [EC:1.5.5.2 1.2.1.88 ]
DAQ1742_01234 dat; D-alanine aminotransferase. Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second-half reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essential bacterial cell wall components [KO:K00824 ] [EC:2.6.1.21 ]
Compound
C00019 S-Adenosyl-L-methionine
C00441 L-Aspartate 4-semialdehyde
C01110 5-Amino-2-oxopentanoic acid
C01137 S-Adenosylmethioninamine
C01165 L-Glutamate 5-semialdehyde
C01250 N-Acetyl-L-glutamate 5-semialdehyde
C03166 Phosphoguanidinoacetate
C03415 N2-Succinyl-L-ornithine
C03564 1-Pyrroline-2-carboxylate
C03771 5-Guanidino-2-oxopentanoate
C03912 (S)-1-Pyrroline-5-carboxylate
C04281 L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147 trans-3-Hydroxy-L-proline
C05932 N-Succinyl-L-glutamate 5-semialdehyde
C05933 N(omega)-Hydroxyarginine
C05938 L-4-Hydroxyglutamate semialdehyde
C05946 (4R)-4-Hydroxy-2-oxoglutarate
C05947 L-erythro-4-Hydroxyglutamate
C15699 gamma-L-Glutamylputrescine
C15700 gamma-Glutamyl-gamma-aminobutyraldehyde
C15767 4-(L-gamma-Glutamylamino)butanoate
C19706 cis-3-Hydroxy-L-proline
Reference
Authors
Haake P, Allen GW.
Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
Journal
Reference
Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
Journal
Reference
Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
Journal
Related pathway
daq00250 Alanine, aspartate and glutamate metabolism
daq00260 Glycine, serine and threonine metabolism
daq00270 Cysteine and methionine metabolism
daq00630 Glyoxylate and dicarboxylate metabolism
daq00770 Pantothenate and CoA biosynthesis
KO pathway
LinkDB
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