KEGG   PATHWAY: drm00230
Entry
drm00230                    Pathway                                
Name
Purine metabolism - Desulforamulus reducens
Class
Metabolism; Nucleotide metabolism
Pathway map
drm00230  Purine metabolism
drm00230

Module
drm_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:drm00230]
drm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:drm00230]
drm_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:drm00230]
drm_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:drm00230]
Other DBs
GO: 0006163 0042278
Organism
Desulforamulus reducens [GN:drm]
Gene
Dred_1901  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Dred_1100  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
Dred_1398  phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
Dred_0100  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Dred_2365  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Dred_2361  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Dred_2363  formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Dred_2366  phosphoribosylformylglycinamidine synthase subunit II [KO:K23269] [EC:6.3.5.3]
Dred_2368  phosphoribosylformylglycinamidine synthase, purS [KO:K23264] [EC:6.3.5.3]
Dred_2367  phosphoribosylformylglycinamidine synthase subunit I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Dred_2364  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Dred_2371  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Dred_2369  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Dred_2370  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Dred_2362  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Dred_0732  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Dred_1760  3'-nucleotidase / 5'-nucleotidase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Dred_0706  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Dred_2376  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Dred_1906  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Dred_0127  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Dred_2683  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Dred_2173  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
Dred_2375  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
Dred_1700  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Dred_0693  ribonucleoside-triphosphate reductase class III catalytic subunit [KO:K21636] [EC:1.1.98.6]
Dred_2464  putative deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Dred_0733  (p)ppGpp synthetase I, SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Dred_1179  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Dred_0123  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Dred_3090  putative Chase2 sensor protein [KO:K01768] [EC:4.6.1.1]
Dred_3300  Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Dred_2771  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
Dred_1917  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
Dred_1718  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Dred_2520  histidine triad (HIT) protein [KO:K19710] [EC:2.7.7.53]
Dred_0635  sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
drm00030  Pentose phosphate pathway
drm00220  Arginine biosynthesis
drm00250  Alanine, aspartate and glutamate metabolism
drm00260  Glycine, serine and threonine metabolism
drm00340  Histidine metabolism
drm00630  Glyoxylate and dicarboxylate metabolism
drm00730  Thiamine metabolism
drm00740  Riboflavin metabolism
drm00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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