KEGG   PATHWAY: dvt00010
Entry
dvt00010                    Pathway                                
Name
Glycolysis / Gluconeogenesis - Daktulosphaira vitifoliae (grape phylloxera)
Description
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].
Class
Metabolism; Carbohydrate metabolism
Pathway map
dvt00010  Glycolysis / Gluconeogenesis
dvt00010

Module
dvt_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:dvt00010]
dvt_M00002  Glycolysis, core module involving three-carbon compounds [PATH:dvt00010]
dvt_M00003  Gluconeogenesis, oxaloacetate => fructose-6P [PATH:dvt00010]
dvt_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:dvt00010]
Other DBs
GO: 0006096 0006094
Organism
Daktulosphaira vitifoliae (grape phylloxera) [GN:dvt]
Gene
126906628  hexokinase type 2 isoform X1 [KO:K00844] [EC:2.7.1.1]
126898305  hexokinase type 2-like [KO:K00844] [EC:2.7.1.1]
126907482  glucose-6-phosphate isomerase [KO:K01810] [EC:5.3.1.9]
126896359  ATP-dependent 6-phosphofructokinase isoform X1 [KO:K00850] [EC:2.7.1.11]
126899459  ATP-dependent 6-phosphofructokinase-like [KO:K00850] [EC:2.7.1.11]
126904034  fructose-1,6-bisphosphatase 1 [KO:K03841] [EC:3.1.3.11]
126906861  fructose-bisphosphate aldolase [KO:K01623] [EC:4.1.2.13]
126897066  triosephosphate isomerase [KO:K01803] [EC:5.3.1.1]
126895986  uncharacterized protein LOC126895986 [KO:K00134] [EC:1.2.1.12]
126896157  glyceraldehyde-3-phosphate dehydrogenase 2-like [KO:K00134] [EC:1.2.1.12]
126898067  uncharacterized protein LOC126898067 [KO:K00134] [EC:1.2.1.12]
126893828  phosphoglycerate kinase [KO:K00927] [EC:2.7.2.3]
126904768  2,3-bisphosphoglycerate-dependent phosphoglycerate mutase-like isoform X1 [KO:K01834] [EC:5.4.2.11]
126907095  phosphoglycerate mutase 2-like [KO:K01834] [EC:5.4.2.11]
126908477  phosphoglycerate mutase 1 [KO:K01834] [EC:5.4.2.11]
126899363  phosphoglycerate mutase 1-like [KO:K01834] [EC:5.4.2.11]
126899364  phosphoglycerate mutase 1-like [KO:K01834] [EC:5.4.2.11]
126908575  enolase [KO:K01689] [EC:4.2.1.11]
126900070  enolase-like isoform X1 [KO:K01689] [EC:4.2.1.11]
126897622  pyruvate kinase-like isoform X1 [KO:K00873] [EC:2.7.1.40]
126908827  pyruvate kinase-like [KO:K00873] [EC:2.7.1.40]
126899280  pyruvate kinase-like [KO:K00873] [EC:2.7.1.40]
126899943  pyruvate kinase-like [KO:K00873] [EC:2.7.1.40]
126902543  probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial isoform X1 [KO:K00161] [EC:1.2.4.1]
126895871  probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [KO:K00161] [EC:1.2.4.1]
126895677  pyruvate dehydrogenase E1 component subunit beta, mitochondrial [KO:K00162] [EC:1.2.4.1]
126902662  dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial-like [KO:K00627] [EC:2.3.1.12]
126894626  dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex-like [KO:K00627] [EC:2.3.1.12]
126902411  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
126900354  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
126908140  1,5-anhydro-D-fructose reductase-like [KO:K00002] [EC:1.1.1.2]
126908142  aldo-keto reductase family 1 member A1-like isoform X1 [KO:K00002] [EC:1.1.1.2]
126908633  aldo-keto reductase family 1 member A1-like isoform X1 [KO:K00002] [EC:1.1.1.2]
126901475  aldehyde dehydrogenase 1A1-like [KO:K00128] [EC:1.2.1.3]
126901476  aldehyde dehydrogenase 1A1-like [KO:K00128] [EC:1.2.1.3]
126901478  aldehyde dehydrogenase 1A1-like [KO:K00128] [EC:1.2.1.3]
126903228  aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
126898787  putative aldehyde dehydrogenase family 7 member A1 homolog [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
126906265  aldehyde dehydrogenase, dimeric NADP-preferring isoform X1 [KO:K00129] [EC:1.2.1.5]
126906373  acetyl-coenzyme A synthetase isoform X1 [KO:K01895] [EC:6.2.1.1]
126906726  galactose mutarotase-like [KO:K01785] [EC:5.1.3.3]
126905274  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
126896344  phosphopentomutase isoform X1 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
126896965  uncharacterized protein LOC126896965 [KO:K01792] [EC:5.1.3.15]
126893991  multiple inositol polyphosphate phosphatase 1-like [KO:K03103] [EC:3.1.3.62 3.1.3.80]
126893992  multiple inositol polyphosphate phosphatase 1-like isoform X1 [KO:K03103] [EC:3.1.3.62 3.1.3.80]
126893993  multiple inositol polyphosphate phosphatase 1-like [KO:K03103] [EC:3.1.3.62 3.1.3.80]
126896294  multiple inositol polyphosphate phosphatase 1-like [KO:K03103] [EC:3.1.3.62 3.1.3.80]
126907952  multiple inositol polyphosphate phosphatase 1-like isoform X1 [KO:K03103] [EC:3.1.3.62 3.1.3.80]
126910381  multiple inositol polyphosphate phosphatase 1-like [KO:K03103] [EC:3.1.3.62 3.1.3.80]
126906561  phosphoenolpyruvate carboxykinase [GTP]-like isoform X1 [KO:K01596] [EC:4.1.1.32]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00031  D-Glucose
C00033  Acetate
C00036  Oxaloacetate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00084  Acetaldehyde
C00085  D-Fructose 6-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00186  (S)-Lactate
C00197  3-Phospho-D-glycerate
C00221  beta-D-Glucose
C00236  3-Phospho-D-glyceroyl phosphate
C00267  alpha-D-Glucose
C00354  D-Fructose 1,6-bisphosphate
C00469  Ethanol
C00631  2-Phospho-D-glycerate
C00668  alpha-D-Glucose 6-phosphate
C01159  2,3-Bisphospho-D-glycerate
C01172  beta-D-Glucose 6-phosphate
C01451  Salicin
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C06186  Arbutin
C06187  Arbutin 6-phosphate
C06188  Salicin 6-phosphate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y (ed).
  Title
[Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1980)
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Michal G.
  Title
Biochemical Pathways
  Journal
Wiley (1999)
Related
pathway
dvt00020  Citrate cycle (TCA cycle)
dvt00030  Pentose phosphate pathway
dvt00500  Starch and sucrose metabolism
dvt00620  Pyruvate metabolism
dvt00640  Propanoate metabolism
KO pathway
ko00010   
LinkDB

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