KEGG   PATHWAY: ebl00330
Entry
ebl00330                    Pathway                                
Name
Arginine and proline metabolism - Escherichia coli BL21(DE3)
Class
Metabolism; Amino acid metabolism
Pathway map
ebl00330  Arginine and proline metabolism
ebl00330

Module
ebl_M00015  Proline biosynthesis, glutamate => proline [PATH:ebl00330]
ebl_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:ebl00330]
ebl_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:ebl00330]
ebl_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:ebl00330]
ebl_M00970  Proline degradation, proline => glutamate [PATH:ebl00330]
Other DBs
GO: 0006525 0006560
Organism
Escherichia coli BL21(DE3) [GN:ebl]
Gene
ECD_00291  codA; cytosine/isoguanine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
ECD_03988  adiA; arginine decarboxylase [KO:K01584] [EC:4.1.1.19]
ECD_02768  speA; biosynthetic arginine decarboxylase, PLP-binding [KO:K01585] [EC:4.1.1.19]
ECD_02767  speB; agmatinase [KO:K01480] [EC:3.5.3.11]
ECD_00649  speF; ornithine decarboxylase isozyme, inducible [KO:K01581] [EC:4.1.1.17]
ECD_02795  speC; ornithine decarboxylase, constitutive [KO:K01581] [EC:4.1.1.17]
ECD_00120  speE; spermidine synthase (putrescine aminopropyltransferase) [KO:K00797] [EC:2.5.1.16]
ECD_00119  speD; S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
ECD_02942  patA; putrescine:2-oxoglutaric acid aminotransferase, PLP-dependent [KO:K09251] [EC:2.6.1.82]
ECD_01401  patD; gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
ECD_01553  speG; spermidine N(1)-acetyltransferase [KO:K00657] [EC:2.3.1.57]
ECD_01716  astA; arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
ECD_01714  astB; succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
ECD_01717  astC; succinylornithine transaminase, PLP-dependent [KO:K00840] [EC:2.6.1.81]
ECD_01715  astD; succinylglutamic semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
ECD_01713  astE; succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
ECD_01274  puuA; glutamate--putrescine ligase [KO:K09470] [EC:6.3.1.11]
ECD_01278  puuB; gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
ECD_01277  puuC; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; succinate semialdehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
ECD_01275  puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
ECD_00333  proC; pyrroline-5-carboxylate reductase, NAD(P)-binding [KO:K00286] [EC:1.5.1.2]
ECD_01017  putA; fused DNA-binding transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
ECD_00239  proB; gamma-glutamate kinase [KO:K00931] [EC:2.7.2.11]
ECD_00240  proA; gamma-glutamylphosphate reductase [KO:K00147] [EC:1.2.1.41]
ECD_00932  aspC; aspartate aminotransferase, PLP-dependent [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ebl00020  Citrate cycle (TCA cycle)
ebl00220  Arginine biosynthesis
ebl00250  Alanine, aspartate and glutamate metabolism
ebl00260  Glycine, serine and threonine metabolism
ebl00270  Cysteine and methionine metabolism
ebl00310  Lysine degradation
ebl00410  beta-Alanine metabolism
ebl00470  D-Amino acid metabolism
ebl00480  Glutathione metabolism
ebl00630  Glyoxylate and dicarboxylate metabolism
ebl00650  Butanoate metabolism
ebl00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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