KEGG   PATHWAY: edj00330
Entry
edj00330                    Pathway                                
Name
Arginine and proline metabolism - Escherichia coli DH1
Class
Metabolism; Amino acid metabolism
Pathway map
edj00330  Arginine and proline metabolism
edj00330

Module
edj_M00015  Proline biosynthesis, glutamate => proline [PATH:edj00330]
edj_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:edj00330]
edj_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:edj00330]
edj_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:edj00330]
edj_M00970  Proline degradation, proline => glutamate [PATH:edj00330]
Other DBs
GO: 0006525 0006560
Organism
Escherichia coli DH1 [GN:edj]
Gene
ECDH1ME8569_0324  codA; cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
ECDH1ME8569_3976  adiA; biodegradative arginine decarboxylase [KO:K01584] [EC:4.1.1.19]
ECDH1ME8569_2838  speA; arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
ECDH1ME8569_2837  speB; agmatinase [KO:K01480] [EC:3.5.3.11]
ECDH1ME8569_0651  speF; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
ECDH1ME8569_2865  speC; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
ECDH1ME8569_0115  speE; spermidine synthase [KO:K00797] [EC:2.5.1.16]
ECDH1ME8569_0114  speD; S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
ECDH1ME8569_2968  ygjG; putrescine:2-oxoglutaric acid aminotransferase, PLP-dependent [KO:K09251] [EC:2.6.1.82]
ECDH1ME8569_1387  ydcW; gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
ECDH1ME8569_1527  speG; spermidine N(1)-acetyltransferase [KO:K00657] [EC:2.3.1.57]
ECDH1ME8569_1691  astA; arginine N-succinyltransferase [KO:K00673] [EC:2.3.1.109]
ECDH1ME8569_1689  astB; succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
ECDH1ME8569_1692  astC; bifunctional succinylornithinetransaminase/acetylornithine transaminase [KO:K00840] [EC:2.6.1.81]
ECDH1ME8569_1690  astD; succinylglutamic semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
ECDH1ME8569_1688  astE; succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
ECDH1ME8569_1239  puuA; conserved hypothetical protein [KO:K09470] [EC:6.3.1.11]
ECDH1ME8569_1243  puuB; gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding [KO:K09471] [EC:1.4.3.-]
ECDH1ME8569_1242  puuC; gamma-glutamyl-gamma-aminobutyraldehydedehydrogenase [KO:K09472] [EC:1.2.1.99]
ECDH1ME8569_1240  puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
ECDH1ME8569_0372  proC; pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
ECDH1ME8569_0968  putA; trifunctional transcriptional regulator/prolinedehydrogenase/pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
ECDH1ME8569_0230  proB; glutamate 5-kinase [KO:K00931] [EC:2.7.2.11]
ECDH1ME8569_0231  proA; gamma-glutamyl phosphate reductase [KO:K00147] [EC:1.2.1.41]
ECDH1ME8569_0879  aspC; aspartate aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
edj00020  Citrate cycle (TCA cycle)
edj00220  Arginine biosynthesis
edj00250  Alanine, aspartate and glutamate metabolism
edj00260  Glycine, serine and threonine metabolism
edj00270  Cysteine and methionine metabolism
edj00310  Lysine degradation
edj00410  beta-Alanine metabolism
edj00470  D-Amino acid metabolism
edj00480  Glutathione metabolism
edj00630  Glyoxylate and dicarboxylate metabolism
edj00650  Butanoate metabolism
edj00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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