KEGG   PATHWAY: ekf00330
Entry
ekf00330                    Pathway                                
Name
Arginine and proline metabolism - Escherichia coli KO11FL
Class
Metabolism; Amino acid metabolism
Pathway map
ekf00330  Arginine and proline metabolism
ekf00330

Module
ekf_M00015  Proline biosynthesis, glutamate => proline [PATH:ekf00330]
ekf_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:ekf00330]
ekf_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:ekf00330]
ekf_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:ekf00330]
ekf_M00970  Proline degradation, proline => glutamate [PATH:ekf00330]
Other DBs
GO: 0006525 0006560
Organism
Escherichia coli KO11FL [GN:ekf]
Gene
KO11_21895  codA; cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
KO11_01750  adiA; arginine decarboxylase [KO:K01584] [EC:4.1.1.19]
KO11_08055  speA; arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
KO11_08065  speB; agmatinase [KO:K01480] [EC:3.5.3.11]
KO11_07920  speC; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
KO11_20270  speF; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
KO11_00580  speE; spermidine synthase [KO:K00797] [EC:2.5.1.16]
KO11_00575  speD; S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
KO11_07355  ygjG; putrescine--2-oxoglutarate aminotransferase [KO:K09251] [EC:2.6.1.82]
KO11_15460  prr; gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
KO11_14835  speG; spermidine N1-acetyltransferase [KO:K00657] [EC:2.3.1.57]
KO11_14000  astA; arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
KO11_14010  astB; succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
KO11_13995  astC; bifunctional succinylornithine transaminase/acetylornithine transaminase [KO:K00840] [EC:2.6.1.81]
KO11_14005  astD; succinylglutamic semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
KO11_14015  astE; succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
KO11_16325  puuA; gamma-glutamylputrescine synthetase [KO:K09470] [EC:6.3.1.11]
KO11_16305  puuD; gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding protein [KO:K09471] [EC:1.4.3.-]
KO11_16310  puuC; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
KO11_16320  puuB; gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
KO11_21670  proC; pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
KO11_17650  putA; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
KO11_22205  proB; gamma-glutamyl kinase [KO:K00931] [EC:2.7.2.11]
KO11_22200  proA; gamma-glutamyl phosphate reductase [KO:K00147] [EC:1.2.1.41]
KO11_18090  aspC; aromatic amino acid aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ekf00020  Citrate cycle (TCA cycle)
ekf00220  Arginine biosynthesis
ekf00250  Alanine, aspartate and glutamate metabolism
ekf00260  Glycine, serine and threonine metabolism
ekf00270  Cysteine and methionine metabolism
ekf00310  Lysine degradation
ekf00410  beta-Alanine metabolism
ekf00470  D-Amino acid metabolism
ekf00480  Glutathione metabolism
ekf00630  Glyoxylate and dicarboxylate metabolism
ekf00650  Butanoate metabolism
ekf00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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