KEGG   PATHWAY: eoc00630
Entry
eoc00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O7:K1 CE10
Class
Metabolism; Carbohydrate metabolism
Pathway map
eoc00630  Glyoxylate and dicarboxylate metabolism
eoc00630

Module
eoc_M00012  Glyoxylate cycle [PATH:eoc00630]
eoc_M00621  Glycine cleavage system [PATH:eoc00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O7:K1 CE10 [GN:eoc]
Gene
CE10_4695  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
CE10_4783  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
CE10_4694  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
CE10_3501  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
CE10_3763  mdh; malate dehydrogenase, NAD(P)-binding protein [KO:K00024] [EC:1.1.1.37]
CE10_0708  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
CE10_1518  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
CE10_0774  ybhJ; hypothetical protein [KO:K01681] [EC:4.2.1.3]
CE10_0118  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
CE10_3272  yqeF; putative acyltransferase [KO:K00626] [EC:2.3.1.9]
CE10_2599  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CE10_3353  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CE10_0731  mutE; glutamate mutase subunit epsilon [KO:K19268] [EC:5.4.99.1]
CE10_0733  mamA; methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
CE10_0730  methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
CE10_3505  glcD; glycolate oxidase subunit, FAD-linked [KO:K00104] [EC:1.1.99.14]
CE10_3504  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
CE10_3503  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
CE10_2011  katE; hydroperoxidase HPII(III) (catalase) [KO:K03781] [EC:1.11.1.6]
CE10_1108  ghrA; glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
CE10_4105  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
CE10_3902  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
CE10_4533  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CE10_2983  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CE10_3341  gcvP; glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex [KO:K00281] [EC:1.4.4.2]
CE10_3343  gcvT; aminomethyltransferase, tetrahydrofolate-dependent, subunit (T protein) of glycine cleavage complex [KO:K00605] [EC:2.1.2.10]
CE10_0116  lpd; lipoamide dehydrogenase, E3 component is part of three enzyme complexes [KO:K00382] [EC:1.8.1.4]
CE10_3342  gcvH; glycine cleavage complex lipoylprotein [KO:K02437]
CE10_0482  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
CE10_0483  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CE10_0484  glxR; tartronate semialdehyde reductase, NADH-dependent [KO:K00042] [EC:1.1.1.60]
CE10_3655  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
CE10_3654  garK; glycerate kinase I [KO:K00865] [EC:2.7.1.165]
CE10_0488  glxK; glycerate kinase II [KO:K00865] [EC:2.7.1.165]
CE10_1614  aldA; aldehyde dehydrogenase A, NAD-linked [KO:K07248] [EC:1.2.1.22 1.2.1.21]
CE10_3225  fucO; L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
CE10_3590  ttdA; L-tartrate dehydratase, alpha subunit [KO:K03779] [EC:4.2.1.32]
CE10_3591  ttdB; L-tartrate dehydratase, beta subunit [KO:K03780] [EC:4.2.1.32]
CE10_2082  dmlA; D-malate oxidase, NAD-dependent, probable tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
CE10_2135  eda; multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CE10_4559  fdoG; formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
CE10_4558  fdoH; formate dehydrogenase-O, Fe-S subunit [KO:K00124]
CE10_4557  fdoI; formate dehydrogenase-O, cytochrome b556 subunit [KO:K00127]
CE10_1409  purU; formyltetrahydrofolate hydrolase [KO:K01433] [EC:3.5.1.10]
CE10_2750  oxc; oxalyl CoA decarboxylase, ThDP-dependent [KO:K01577] [EC:4.1.1.8]
CE10_2751  frc; formyl-CoA transferase, NAD(P)-binding protein [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
eoc00010  Glycolysis / Gluconeogenesis
eoc00020  Citrate cycle (TCA cycle)
eoc00030  Pentose phosphate pathway
eoc00053  Ascorbate and aldarate metabolism
eoc00071  Fatty acid degradation
eoc00230  Purine metabolism
eoc00250  Alanine, aspartate and glutamate metabolism
eoc00260  Glycine, serine and threonine metabolism
eoc00620  Pyruvate metabolism
eoc00710  Carbon fixation by Calvin cycle
eoc00750  Vitamin B6 metabolism
eoc00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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