KEGG   PATHWAY: esl00630
Entry
esl00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O104:H4 2011C-3493 (EAEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
esl00630  Glyoxylate and dicarboxylate metabolism
esl00630

Module
esl_M00012  Glyoxylate cycle [PATH:esl00630]
esl_M00621  Glycine cleavage system [PATH:esl00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O104:H4 2011C-3493 (EAEC) [GN:esl]
Gene
O3K_23805  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
O3K_23505  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
O3K_04080  malate synthase G [KO:K01638] [EC:2.3.3.9]
O3K_23810  malate synthase [KO:K01638] [EC:2.3.3.9]
O3K_02785  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
O3K_18045  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
O3K_13960  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
O3K_17815  putative hydratase [KO:K01681] [EC:4.2.1.3]
O3K_20975  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
O3K_05290  putative acyltransferase [KO:K00626] [EC:2.3.1.9]
O3K_04885  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
O3K_04890  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
O3K_04060  glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
O3K_04065  glcE; glycolate oxidase FAD binding subunit [KO:K11472] [EC:1.1.99.14]
O3K_04070  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
O3K_11305  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
O3K_15390  ghrA; bifunctional glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
O3K_01095  bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
O3K_02145  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
O3K_24530  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
O3K_06660  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
O3K_04950  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
O3K_04940  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
O3K_20985  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
O3K_04945  glycine cleavage system protein H [KO:K02437]
O3K_18960  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
O3K_18955  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
O3K_18950  tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
O3K_03320  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
O3K_03325  glycerate kinase I [KO:K00865] [EC:2.7.1.165]
O3K_18930  glycerate kinase II [KO:K00865] [EC:2.7.1.165]
O3K_13420  aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
O3K_05500  L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
O3K_03645  tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
O3K_03640  L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
O3K_10950  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
O3K_10685  keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
O3K_24395  formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.17.1.9]
O3K_24400  formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
O3K_24405  formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
O3K_24410  formate dehydrogenase-O subunit gamma [KO:K00127]
O3K_14490  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
O3K_07505  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
O3K_07500  formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
esl00010  Glycolysis / Gluconeogenesis
esl00020  Citrate cycle (TCA cycle)
esl00030  Pentose phosphate pathway
esl00053  Ascorbate and aldarate metabolism
esl00071  Fatty acid degradation
esl00230  Purine metabolism
esl00250  Alanine, aspartate and glutamate metabolism
esl00260  Glycine, serine and threonine metabolism
esl00620  Pyruvate metabolism
esl00710  Carbon fixation by Calvin cycle
esl00750  Vitamin B6 metabolism
esl00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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