KEGG   PATHWAY: esz00620
Entry
esz00620                    Pathway                                
Name
Pyruvate metabolism - Escherichia sp. E4742
Class
Metabolism; Carbohydrate metabolism
Pathway map
esz00620  Pyruvate metabolism
esz00620

Module
esz_M00168  CAM (Crassulacean acid metabolism), dark [PATH:esz00620]
esz_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:esz00620]
esz_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:esz00620]
Other DBs
GO: 0006090
Organism
Escherichia sp. E4742 [GN:esz]
Gene
FEM44_12215  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
FEM44_22120  nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase [KO:K03737] [EC:1.2.7.1 1.2.7.-]
FEM44_15045  aceE; pyruvate dehydrogenase (acetyl-transferring), homodimeric type [KO:K00163] [EC:1.2.4.1]
FEM44_15050  aceF; pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase [KO:K00627] [EC:2.3.1.12]
FEM44_15055  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
FEM44_19090  pflB; formate C-acetyltransferase [KO:K00656] [EC:2.3.1.54]
FEM44_06635  tdcE; 2-ketobutyrate formate-lyase/pyruvate formate-lyase [KO:K00656] [EC:2.3.1.54]
FEM44_21250  adhE; bifunctional acetaldehyde-CoA/alcohol dehydrogenase [KO:K04072] [EC:1.2.1.10 1.1.1.1]
FEM44_16330  acetaldehyde dehydrogenase (acetylating) [KO:K04073] [EC:1.2.1.10]
FEM44_02285  aldehyde dehydrogenase EutE [KO:K04021]
FEM44_22485  adhP; alcohol dehydrogenase AdhP [KO:K13953] [EC:1.1.1.1]
FEM44_11135  yiaY; L-threonine dehydrogenase [KO:K13954] [EC:1.1.1.1]
FEM44_16355  S-(hydroxymethyl)glutathione dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
FEM44_16200  yahK; NADPH-dependent aldehyde reductase YahK [KO:K13979] [EC:1.1.1.2]
FEM44_02275  eutG; ethanolamine utilization ethanol dehydrogenase EutG [KO:K04022]
FEM44_01660  acetate kinase [KO:K00925] [EC:2.7.2.1]
FEM44_01665  phosphate acetyltransferase [KO:K13788] [EC:2.3.1.8]
FEM44_02300  pta; phosphate acetyltransferase [KO:K04020]
FEM44_24175  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
FEM44_23315  pykF; pyruvate kinase PykF [KO:K00873] [EC:2.7.1.40]
FEM44_15405  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
FEM44_07275  accB; acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
FEM44_07280  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
FEM44_01760  accD; acetyl-CoA carboxylase, carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
FEM44_19415  acylphosphatase [KO:K01512] [EC:3.6.1.7]
FEM44_11140  aldehyde dehydrogenase [KO:K00138] [EC:1.2.1.-]
FEM44_13700  acyl CoA:acetate/3-ketoacid CoA transferase [KO:K01026] [EC:2.8.3.1]
FEM44_11025  lldD; quinone-dependent L-lactate dehydrogenase [KO:K00101] [EC:1.1.2.3]
FEM44_18885  poxB; ubiquinone-dependent pyruvate dehydrogenase [KO:K00156] [EC:1.2.5.1]
FEM44_22135  ldhA; D-lactate dehydrogenase [KO:K03778] [EC:1.1.1.28]
FEM44_00890  D-lactate dehydrogenase [KO:K03777] [EC:1.1.5.12]
FEM44_22180  aldA; aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
FEM44_23185  gloA; lactoylglutathione lyase [KO:K01759] [EC:4.4.1.5]
FEM44_19210  gloC; hydroxyacylglutathione hydrolase GloC [KO:K01069] [EC:3.1.2.6]
FEM44_15545  gloB; hydroxyacylglutathione hydrolase [KO:K01069] [EC:3.1.2.6]
FEM44_24790  hchA; protein deglycase HchA [KO:K05523] [EC:4.2.1.130 3.5.1.124]
FEM44_20000  ghrA; glyoxylate/hydroxypyruvate reductase GhrA [KO:K12972] [EC:1.1.1.79 1.1.1.81]
FEM44_08945  ghrB; glyoxylate/hydroxypyruvate reductase GhrB [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
FEM44_22490  NAD-dependent malic enzyme [KO:K00027] [EC:1.1.1.38]
FEM44_02325  NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase [KO:K00029] [EC:1.1.1.40]
FEM44_07180  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
FEM44_01280  mqo; malate dehydrogenase (quinone) [KO:K00116] [EC:1.1.5.4]
FEM44_12435  fumarate hydratase [KO:K01676] [EC:4.2.1.2]
FEM44_22985  fumarate hydratase [KO:K01676] [EC:4.2.1.2]
FEM44_18095  class I fumarate hydratase [KO:K01676] [EC:4.2.1.2]
FEM44_22980  fumC; class II fumarate hydratase [KO:K01679] [EC:4.2.1.2]
FEM44_23310  fumD; fumarate hydratase FumD [KO:K01675] [EC:4.2.1.2]
FEM44_04545  fumE; fumarase E [KO:K01774] [EC:4.2.1.2]
FEM44_13435  frdA; fumarate reductase (quinol) flavoprotein subunit [KO:K00244] [EC:1.3.5.1]
FEM44_13430  succinate dehydrogenase/fumarate reductase iron-sulfur subunit [KO:K00245] [EC:1.3.5.1]
FEM44_13425  frdC; fumarate reductase subunit FrdC [KO:K00246]
FEM44_13420  frdD; fumarate reductase subunit FrdD [KO:K00247]
FEM44_11485  phosphoenolpyruvate carboxylase [KO:K01595] [EC:4.1.1.31]
FEM44_07965  pckA; phosphoenolpyruvate carboxykinase (ATP) [KO:K01610] [EC:4.1.1.49]
FEM44_23450  ppsA; phosphoenolpyruvate synthase [KO:K01007] [EC:2.7.9.2]
FEM44_05900  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
FEM44_11805  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
FEM44_04155  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
FEM44_14855  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
esz00010  Glycolysis / Gluconeogenesis
esz00020  Citrate cycle (TCA cycle)
esz00061  Fatty acid biosynthesis
esz00250  Alanine, aspartate and glutamate metabolism
esz00260  Glycine, serine and threonine metabolism
esz00290  Valine, leucine and isoleucine biosynthesis
esz00300  Lysine biosynthesis
esz00630  Glyoxylate and dicarboxylate metabolism
esz00640  Propanoate metabolism
esz00650  Butanoate metabolism
esz00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   
LinkDB

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