KEGG   PATHWAY: halq00630
Entry
halq00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halorubrum sp. CBA1229
Class
Metabolism; Carbohydrate metabolism
Pathway map
halq00630  Glyoxylate and dicarboxylate metabolism
halq00630

Module
halq_M00621  Glycine cleavage system [PATH:halq00630]
halq_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:halq00630]
halq_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:halq00630]
Other DBs
GO: 0046487 0043648
Organism
Halorubrum sp. CBA1229 [GN:halq]
Gene
Hrr1229_011330  isocitrate lyase/PEP mutase family protein [KO:K01637] [EC:4.1.3.1 4.1.3.30]
Hrr1229_002260  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
Hrr1229_015325  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Hrr1229_015340  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Hrr1229_007305  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Hrr1229_002665  citrate synthase [KO:K01659] [EC:2.3.3.5]
Hrr1229_017885  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
Hrr1229_016740  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
Hrr1229_000150  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Hrr1229_003235  thiolase family protein [KO:K00626] [EC:2.3.1.9]
Hrr1229_010785  thiolase family protein [KO:K00626] [EC:2.3.1.9]
Hrr1229_014010  MaoC family dehydratase N-terminal domain-containing protein [KO:K17865] [EC:4.2.1.55]
Hrr1229_000110  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Hrr1229_007910  carbamoyl phosphate synthase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
Hrr1229_007925  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Hrr1229_007920  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
Hrr1229_004230  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
Hrr1229_000070  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
Hrr1229_000100  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
Hrr1229_012095  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
Hrr1229_002125  HAD-IIB family hydrolase [KO:K22223] [EC:3.1.3.18]
Hrr1229_015775  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Hrr1229_002420  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
Hrr1229_008820  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
Hrr1229_009895  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Hrr1229_013230  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
Hrr1229_013235  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
Hrr1229_004605  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
Hrr1229_015545  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
Hrr1229_006210  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Hrr1229_013225  gcvH; glycine cleavage system protein GcvH [KO:K02437]
Hrr1229_005020  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
Hrr1229_017495  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
Hrr1229_009485  HAD-IA family hydrolase [KO:K26210] [EC:3.1.3.109]
Hrr1229_009490  class II aldolase/adducin family protein [KO:K01636] [EC:4.1.2.-]
Hrr1229_010810  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Hrr1229_006170  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Hrr1229_010850  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Hrr1229_015495  ACT domain-containing protein [KO:K01433] [EC:3.5.1.10]
Hrr1229_007615  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
halq00010  Glycolysis / Gluconeogenesis
halq00020  Citrate cycle (TCA cycle)
halq00030  Pentose phosphate pathway
halq00053  Ascorbate and aldarate metabolism
halq00071  Fatty acid degradation
halq00230  Purine metabolism
halq00250  Alanine, aspartate and glutamate metabolism
halq00260  Glycine, serine and threonine metabolism
halq00620  Pyruvate metabolism
halq00710  Carbon fixation by Calvin cycle
halq00750  Vitamin B6 metabolism
halq00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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