KEGG   PATHWAY: hazp00630
Entry
hazp00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halomicrobium sp. ZPS1
Class
Metabolism; Carbohydrate metabolism
Pathway map
hazp00630  Glyoxylate and dicarboxylate metabolism
hazp00630

Module
hazp_M00621  Glycine cleavage system [PATH:hazp00630]
hazp_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hazp00630]
hazp_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:hazp00630]
Other DBs
GO: 0046487 0043648
Organism
Halomicrobium sp. ZPS1 [GN:hazp]
Gene
GBQ70_13430  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
GBQ70_13995  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
GBQ70_07180  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
GBQ70_07360  citrate synthase [KO:K01647] [EC:2.3.3.1]
GBQ70_06135  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
GBQ70_14575  thiolase family protein [KO:K00626] [EC:2.3.1.9]
GBQ70_01335  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
GBQ70_08090  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
GBQ70_01715  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
GBQ70_02190  acyl dehydratase [KO:K14449] [EC:4.2.1.148]
GBQ70_00145  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
GBQ70_00135  methylmalonyl-CoA carboxyltransferase [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
GBQ70_14560  methylmalonyl-CoA carboxyltransferase [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
GBQ70_14565  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
GBQ70_01315  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
GBQ70_01725  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
GBQ70_13985  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
GBQ70_02180  methylaspartate mutase subunit E [KO:K19268] [EC:5.4.99.1]
GBQ70_02175  methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
GBQ70_02185  methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
GBQ70_02170  CoA transferase [KO:K19280] [EC:2.8.3.26]
GBQ70_02195  citrate lyase subunit beta [KO:K19281] [EC:4.1.3.24]
GBQ70_11170  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
GBQ70_13580  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GBQ70_12170  HAD-IIB family hydrolase [KO:K22223] [EC:3.1.3.18]
GBQ70_01130  rbcL; type III ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
GBQ70_02915  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
GBQ70_06720  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GBQ70_01740  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
GBQ70_14230  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GBQ70_12610  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
GBQ70_12615  aminotransferase class V-fold PLP-dependent enzyme [KO:K00283] [EC:1.4.4.2]
GBQ70_04620  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
GBQ70_12595  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
GBQ70_08080  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GBQ70_12600  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GBQ70_09310  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GBQ70_10255  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hazp00010  Glycolysis / Gluconeogenesis
hazp00020  Citrate cycle (TCA cycle)
hazp00030  Pentose phosphate pathway
hazp00053  Ascorbate and aldarate metabolism
hazp00071  Fatty acid degradation
hazp00230  Purine metabolism
hazp00250  Alanine, aspartate and glutamate metabolism
hazp00260  Glycine, serine and threonine metabolism
hazp00620  Pyruvate metabolism
hazp00710  Carbon fixation by Calvin cycle
hazp00750  Vitamin B6 metabolism
hazp00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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