KEGG   PATHWAY: hwa00230
Entry
hwa00230                    Pathway                                
Name
Purine metabolism - Haloquadratum walsbyi DSM 16790
Class
Metabolism; Nucleotide metabolism
Pathway map
hwa00230  Purine metabolism
hwa00230

Module
hwa_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hwa00230]
hwa_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hwa00230]
hwa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hwa00230]
Other DBs
GO: 0006163 0042278
Organism
Haloquadratum walsbyi DSM 16790 [GN:hwa]
Gene
HQ_3163A  NUDIX family hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HQ_3084A  NUDIX family hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HQ_1024A  pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) [KO:K15778] [EC:5.4.2.8 5.4.2.2]
HQ_3650A  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
HQ_2893A  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HQ_2560A  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HQ_1661A  purNH; phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K01492] [EC:2.1.2.2 2.1.2.3]
HQ_1464A  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
HQ_1693A  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
HQ_3130A  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
HQ_3131A  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
HQ_2665A  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
HQ_1635A  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
HQ_1636A  purE1; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
HQ_3128A  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HQ_1662A  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HQ_1006A  purO; inosine-5'-monophosphate cyclohydrolase, archaeal-type [KO:K11176] [EC:3.5.4.10]
HQ_3228A  apt3; purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase) [KO:K00759] [EC:2.4.2.7]
HQ_1672A  apt1; purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase) [KO:K00759] [EC:2.4.2.7]
HQ_2050A  apt2; purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase) [KO:K00759] [EC:2.4.2.7]
HQ_3350A  surE1; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HQ_3676A  surE2; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HQ_2270A  HAD superfamily hydrolase [KO:K02566] [EC:3.1.3.5]
HQ_2382A  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
HQ_2882A  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HQ_1343A  ham1; non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
HQ_3194A  guaAb; GMP synthase (glutamine-hydrolyzing) subunit B [KO:K01951] [EC:6.3.5.2]
HQ_1289A  guaAa1; GMP synthase (glutamine-hydrolyzing) subunit A [KO:K01951] [EC:6.3.5.2]
HQ_3668A  guaAa2; glutamine amidotransferase (homolog to GMP synthase subunit A) [KO:K01951] [EC:6.3.5.2]
HQ_2947A  glutamine amidotransferase (homolog to GMP synthase subunit A) [KO:K01951] [EC:6.3.5.2]
HQ_3201A  udp3; uridine phosphorylase [KO:K26212] [EC:2.4.2.15]
HQ_2859A  nrdJ; ribonucleoside-diphosphate reductase,adenosylcobalamin-dependent (intein-containing) [KO:K00525] [EC:1.17.4.1]
HQ_2585A  adenylate cyclase domain protein [KO:K05873] [EC:4.6.1.1]
HQ_1660A  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
HQ_1449A  adkA; adenylate kinase (ATP-AMP transphosphorylase),archaeal-type [KO:K00939] [EC:2.7.4.3]
HQ_2767A  adk1; adenylate kinase [KO:K00939] [EC:2.7.4.3]
HQ_3363A  adk2; probable adenylate kinase [KO:K18532] [EC:2.7.4.3]
HQ_2045A  probable phosphoesterase [KO:K03651] [EC:3.1.4.53]
HQ_3207A  hit1; histidine triad family protein (homolog to bis(5'-nucleosyl)-tetraphosphatase) [KO:K19710] [EC:2.7.7.53]
HQ_3626A  ureC; urease alpha subunit [KO:K01428] [EC:3.5.1.5]
HQ_3625A  ureB; urease beta subunit [KO:K01429] [EC:3.5.1.5]
HQ_3627A  ureA; urease gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
hwa00030  Pentose phosphate pathway
hwa00220  Arginine biosynthesis
hwa00250  Alanine, aspartate and glutamate metabolism
hwa00260  Glycine, serine and threonine metabolism
hwa00340  Histidine metabolism
hwa00630  Glyoxylate and dicarboxylate metabolism
hwa00730  Thiamine metabolism
hwa00740  Riboflavin metabolism
hwa00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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