KEGG   PATHWAY: kom00630
Entry
kom00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Klebsiella michiganensis M1
Class
Metabolism; Carbohydrate metabolism
Pathway map
kom00630  Glyoxylate and dicarboxylate metabolism
kom00630

Module
kom_M00012  Glyoxylate cycle [PATH:kom00630]
kom_M00621  Glycine cleavage system [PATH:kom00630]
Other DBs
GO: 0046487 0043648
Organism
Klebsiella michiganensis M1 [GN:kom]
Gene
HR38_06720  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
HR38_07140  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
HR38_06715  malate synthase [KO:K01638] [EC:2.3.3.9]
HR38_02545  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
HR38_23340  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
HR38_13340  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
HR38_16705  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
HR38_09310  hydratase [KO:K01681] [EC:4.2.1.3]
HR38_09805  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
HR38_00255  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
HR38_00485  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
HR38_00910  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
HR38_13445  glutamate mutase [KO:K19268] [EC:5.4.99.1]
HR38_13455  methylaspartate mutase [KO:K01846] [EC:5.4.99.1]
HR38_13440  methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
HR38_24345  catalase [KO:K03781] [EC:1.11.1.6]
HR38_16515  katE; hydroperoxidase [KO:K03781] [EC:1.11.1.6]
HR38_26345  2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
HR38_15635  ghrA; bifunctional glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
HR38_04040  bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
HR38_03155  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
HR38_05400  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
HR38_25585  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
HR38_00850  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
HR38_00860  gcvT; glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
HR38_09785  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
HR38_18775  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
HR38_00855  glycine cleavage system protein H [KO:K02437]
HR38_02025  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
HR38_02020  glycerate kinase [KO:K00865] [EC:2.7.1.165]
HR38_00505  glycerate kinase [KO:K00865] [EC:2.7.1.165]
HR38_27295  glycerate kinase [KO:K00865] [EC:2.7.1.165]
HR38_17865  aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
HR38_26965  1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
HR38_02520  tartrate dehydratase [KO:K03779] [EC:4.2.1.32]
HR38_02515  fumarate hydrolyase [KO:K03780] [EC:4.2.1.32]
HR38_15425  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
HR38_22155  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
HR38_05450  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
HR38_05455  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
HR38_05445  formate dehydrogenase [KO:K00124]
HR38_05440  formate dehydrogenase [KO:K00127]
HR38_21360  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
HR38_27755  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
HR38_10725  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
kom00010  Glycolysis / Gluconeogenesis
kom00020  Citrate cycle (TCA cycle)
kom00030  Pentose phosphate pathway
kom00053  Ascorbate and aldarate metabolism
kom00071  Fatty acid degradation
kom00230  Purine metabolism
kom00250  Alanine, aspartate and glutamate metabolism
kom00260  Glycine, serine and threonine metabolism
kom00620  Pyruvate metabolism
kom00710  Carbon fixation by Calvin cycle
kom00750  Vitamin B6 metabolism
kom00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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