KEGG   PATHWAY: kpk00330
Entry
kpk00330                    Pathway                                
Name
Arginine and proline metabolism - Klebsiella variicola KP5-1
Class
Metabolism; Amino acid metabolism
Pathway map
kpk00330  Arginine and proline metabolism
kpk00330

Module
kpk_M00015  Proline biosynthesis, glutamate => proline [PATH:kpk00330]
kpk_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:kpk00330]
kpk_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:kpk00330]
kpk_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:kpk00330]
kpk_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:kpk00330]
kpk_M00970  Proline degradation, proline => glutamate [PATH:kpk00330]
Other DBs
GO: 0006525 0006560
Organism
Klebsiella variicola KP5-1 [GN:kpk]
Gene
A593_25140  creatinine amidohydrolase [KO:K01470] [EC:3.5.2.10]
A593_08950  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
A593_17625  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
A593_25130  hypothetical protein [KO:K01485] [EC:3.5.4.1 3.5.4.21]
A593_06975  arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
A593_06970  agmatinase [KO:K01480] [EC:3.5.3.11]
A593_07095  ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
A593_15045  spermidine synthase [KO:K00797] [EC:2.5.1.16]
A593_15040  S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
A593_07755  putrescine--2-oxoglutarate aminotransferase [KO:K09251] [EC:2.6.1.82]
A593_24485  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
A593_22490  spermidine acetyltransferase [KO:K00657] [EC:2.3.1.57]
A593_05040  agmatinase [KO:K12255] [EC:3.5.3.7]
A593_23240  amidase [KO:K01426] [EC:3.5.1.4]
A593_22020  arginine N-succinyltransferase [KO:K00673] [EC:2.3.1.109]
A593_20840  arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
A593_22030  N-succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
A593_20850  succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
A593_22015  argD; acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
A593_20835  acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
A593_22025  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
A593_20845  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
A593_22035  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
A593_20855  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
A593_19605  gamma-glutamylputrescine synthetase [KO:K09470] [EC:6.3.1.11]
A593_19585  gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
A593_17105  FAD-dependent oxidoreductase [KO:K09471] [EC:1.4.3.-]
A593_19590  aldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
A593_19600  gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
A593_19770  arginase [KO:K01476] [EC:3.5.3.1]
A593_02955  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
A593_16025  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
A593_19705  putA; transcriptional regulator [KO:K13821] [EC:1.5.5.2 1.2.1.88]
A593_15780  gamma-glutamyl kinase [KO:K00931] [EC:2.7.2.11]
A593_15775  gamma-glutamyl phosphate reductase [KO:K00147] [EC:1.2.1.41]
A593_20480  aspartate aminotransferase [KO:K00812] [EC:2.6.1.1]
A593_19295  aromatic amino acid aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
kpk00020  Citrate cycle (TCA cycle)
kpk00220  Arginine biosynthesis
kpk00250  Alanine, aspartate and glutamate metabolism
kpk00260  Glycine, serine and threonine metabolism
kpk00270  Cysteine and methionine metabolism
kpk00310  Lysine degradation
kpk00410  beta-Alanine metabolism
kpk00470  D-Amino acid metabolism
kpk00480  Glutathione metabolism
kpk00630  Glyoxylate and dicarboxylate metabolism
kpk00650  Butanoate metabolism
kpk00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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