KEGG   PATHWAY: kpnu00330
Entry
kpnu00330                   Pathway                                
Name
Arginine and proline metabolism - Klebsiella pneumoniae 34618
Class
Metabolism; Amino acid metabolism
Pathway map
kpnu00330  Arginine and proline metabolism
kpnu00330

Module
kpnu_M00015  Proline biosynthesis, glutamate => proline [PATH:kpnu00330]
kpnu_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:kpnu00330]
kpnu_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:kpnu00330]
kpnu_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:kpnu00330]
kpnu_M00970  Proline degradation, proline => glutamate [PATH:kpnu00330]
Other DBs
GO: 0006525 0006560
Organism
Klebsiella pneumoniae 34618 [GN:kpnu]
Gene
LI86_11160  creatinine amidohydrolase [KO:K01470] [EC:3.5.2.10]
LI86_18945  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
LI86_11170  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
LI86_01875  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
LI86_04215  arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
LI86_04220  agmatinase [KO:K01480] [EC:3.5.3.11]
LI86_04090  ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
LI86_22090  spermidine synthase [KO:K00797] [EC:2.5.1.16]
LI86_22095  S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
LI86_03245  putrescine--2-oxoglutarate aminotransferase [KO:K09251] [EC:2.6.1.82]
LI86_11765  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
LI86_13675  spermidine acetyltransferase [KO:K00657] [EC:2.3.1.57]
LI86_06265  agmatinase [KO:K12255] [EC:3.5.3.7]
LI86_15905  arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
LI86_14150  arginine N-succinyltransferase [KO:K00673] [EC:2.3.1.109]
LI86_15895  succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
LI86_14140  N-succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
LI86_15910  acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
LI86_14155  argD; acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
LI86_15900  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
LI86_14145  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
LI86_15890  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
LI86_14135  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
LI86_16970  gamma-glutamylputrescine synthetase [KO:K09470] [EC:6.3.1.11]
LI86_19505  FAD-dependent oxidoreductase [KO:K09471] [EC:1.4.3.-]
LI86_16990  gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
LI86_16985  aldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
LI86_16975  gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
LI86_20970  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
LI86_16865  putA; transcriptional regulator [KO:K13821] [EC:1.5.5.2 1.2.1.88]
LI86_21230  gamma-glutamyl kinase [KO:K00931] [EC:2.7.2.11]
LI86_21235  gamma-glutamyl phosphate reductase [KO:K00147] [EC:1.2.1.41]
LI86_17260  aromatic amino acid aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
kpnu00020  Citrate cycle (TCA cycle)
kpnu00220  Arginine biosynthesis
kpnu00250  Alanine, aspartate and glutamate metabolism
kpnu00260  Glycine, serine and threonine metabolism
kpnu00270  Cysteine and methionine metabolism
kpnu00310  Lysine degradation
kpnu00410  beta-Alanine metabolism
kpnu00470  D-Amino acid metabolism
kpnu00480  Glutathione metabolism
kpnu00630  Glyoxylate and dicarboxylate metabolism
kpnu00650  Butanoate metabolism
kpnu00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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