KEGG   PATHWAY: kpq00330
Entry
kpq00330                    Pathway                                
Name
Arginine and proline metabolism - Klebsiella pneumoniae subsp. pneumoniae KPR0928
Class
Metabolism; Amino acid metabolism
Pathway map
kpq00330  Arginine and proline metabolism
kpq00330

Module
kpq_M00015  Proline biosynthesis, glutamate => proline [PATH:kpq00330]
kpq_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:kpq00330]
kpq_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:kpq00330]
kpq_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:kpq00330]
kpq_M00970  Proline degradation, proline => glutamate [PATH:kpq00330]
Other DBs
GO: 0006525 0006560
Organism
Klebsiella pneumoniae subsp. pneumoniae KPR0928 [GN:kpq]
Gene
KPR0928_14900  creatinine amidohydrolase [KO:K01470] [EC:3.5.2.10]
KPR0928_23925  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
KPR0928_14890  hypothetical protein [KO:K01485] [EC:3.5.4.1 3.5.4.21]
KPR0928_07235  cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
KPR0928_21635  arginine decarboxylase [KO:K01585] [EC:4.1.1.19]
KPR0928_21630  agmatinase [KO:K01480] [EC:3.5.3.11]
KPR0928_21755  ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
KPR0928_04270  spermidine synthase [KO:K00797] [EC:2.5.1.16]
KPR0928_04265  S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
KPR0928_22595  putrescine--2-oxoglutarate aminotransferase [KO:K09251] [EC:2.6.1.82]
KPR0928_14305  gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
KPR0928_12450  spermidine acetyltransferase [KO:K00657] [EC:2.3.1.57]
KPR0928_19630  agmatinase [KO:K12255] [EC:3.5.3.7]
KPR0928_10680  arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
KPR0928_12000  arginine N-succinyltransferase [KO:K00673] [EC:2.3.1.109]
KPR0928_10690  succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
KPR0928_12010  N-succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
KPR0928_10675  acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
KPR0928_11995  argD; acetylornithine aminotransferase [KO:K00840] [EC:2.6.1.81]
KPR0928_10685  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
KPR0928_12005  astD; succinylglutamate-semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
KPR0928_10695  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
KPR0928_12015  succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
KPR0928_09665  gamma-glutamylputrescine synthetase [KO:K09470] [EC:6.3.1.11]
KPR0928_09645  gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
KPR0928_06695  FAD-dependent oxidoreductase [KO:K09471] [EC:1.4.3.-]
KPR0928_09650  aldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
KPR0928_09660  gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
KPR0928_05265  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
KPR0928_09770  putA; transcriptional regulator [KO:K13821] [EC:1.5.5.2 1.2.1.88]
KPR0928_05015  gamma-glutamyl kinase [KO:K00931] [EC:2.7.2.11]
KPR0928_05010  gamma-glutamyl phosphate reductase [KO:K00147] [EC:1.2.1.41]
KPR0928_09100  aromatic amino acid aminotransferase [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
kpq00020  Citrate cycle (TCA cycle)
kpq00220  Arginine biosynthesis
kpq00250  Alanine, aspartate and glutamate metabolism
kpq00260  Glycine, serine and threonine metabolism
kpq00270  Cysteine and methionine metabolism
kpq00310  Lysine degradation
kpq00410  beta-Alanine metabolism
kpq00470  D-Amino acid metabolism
kpq00480  Glutathione metabolism
kpq00630  Glyoxylate and dicarboxylate metabolism
kpq00650  Butanoate metabolism
kpq00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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