KEGG   PATHWAY: mee00630
Entry
mee00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Methylobacterium currus
Class
Metabolism; Carbohydrate metabolism
Pathway map
mee00630  Glyoxylate and dicarboxylate metabolism
mee00630

Module
mee_M00621  Glycine cleavage system [PATH:mee00630]
mee_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mee00630]
Other DBs
GO: 0046487 0043648
Organism
Methylobacterium currus [GN:mee]
Gene
DA075_01200  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DA075_19660  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DA075_20600  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DA075_26600  malate synthase G [KO:K01638] [EC:2.3.3.9]
DA075_12060  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DA075_13390  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DA075_23620  helix-turn-helix domain-containing protein [KO:K01647] [EC:2.3.3.1]
DA075_31595  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
DA075_26545  succinate--CoA ligase subunit alpha [KO:K08692] [EC:6.2.1.9]
DA075_26540  ADP-forming succinate--CoA ligase subunit beta [KO:K14067] [EC:6.2.1.9]
DA075_30625  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DA075_14420  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DA075_23330  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DA075_19060  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DA075_10730  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DA075_15030  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DA075_02695  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DA075_02710  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DA075_23335  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DA075_07285  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
DA075_05075  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
DA075_08645  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DA075_05080  protein meaA [KO:K14447] [EC:5.4.99.63]
DA075_26015  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
DA075_14875  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
DA075_27160  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
DA075_20140  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
DA075_23345  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
DA075_15385  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
DA075_30050  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DA075_04210  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DA075_01085  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DA075_23120  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
DA075_19760  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
DA075_16765  catalase [KO:K03781] [EC:1.11.1.6]
DA075_08770  catalase [KO:K03781] [EC:1.11.1.6]
DA075_06995  catalase [KO:K03781] [EC:1.11.1.6]
DA075_21185  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
DA075_25435  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DA075_12830  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DA075_21800  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DA075_26525  D-2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
DA075_21650  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
DA075_26495  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DA075_07105  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DA075_26520  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
DA075_02165  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DA075_32975  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DA075_15575  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DA075_00460  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DA075_15275  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DA075_12340  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
DA075_12350  glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DA075_12030  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DA075_04155  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DA075_26150  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DA075_06270  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DA075_15650  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DA075_12345  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DA075_07705  glycerate kinase [KO:K11529] [EC:2.7.1.165]
DA075_07480  glycerate kinase [KO:K11529] [EC:2.7.1.165]
DA075_23700  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DA075_07475  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DA075_01550  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DA075_29550  cupin domain-containing protein [KO:K01569] [EC:4.1.1.2]
DA075_00570  cupin domain-containing protein [KO:K01569] [EC:4.1.1.2]
DA075_02720  cupin domain-containing protein [KO:K01569] [EC:4.1.1.2]
DA075_22785  peptidase [KO:K00126] [EC:1.17.1.9]
DA075_22795  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DA075_27385  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
DA075_22800  formate dehydrogenase [KO:K00124]
DA075_27390  4Fe-4S dicluster domain-containing protein [KO:K00124]
DA075_22805  formate dehydrogenase subunit gamma [KO:K00127]
DA075_27395  formate dehydrogenase subunit gamma [KO:K00127]
DA075_23480  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
DA075_24345  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
DA075_19945  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mee00010  Glycolysis / Gluconeogenesis
mee00020  Citrate cycle (TCA cycle)
mee00030  Pentose phosphate pathway
mee00053  Ascorbate and aldarate metabolism
mee00071  Fatty acid degradation
mee00230  Purine metabolism
mee00250  Alanine, aspartate and glutamate metabolism
mee00260  Glycine, serine and threonine metabolism
mee00620  Pyruvate metabolism
mee00710  Carbon fixation by Calvin cycle
mee00750  Vitamin B6 metabolism
mee00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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