KEGG   PATHWAY: mku00630
Entry
mku00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium kubicae
Class
Metabolism; Carbohydrate metabolism
Pathway map
mku00630  Glyoxylate and dicarboxylate metabolism
mku00630

Module
mku_M00012  Glyoxylate cycle [PATH:mku00630]
mku_M00621  Glycine cleavage system [PATH:mku00630]
mku_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mku00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium kubicae [GN:mku]
Gene
I2456_04095  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
I2456_13895  isocitrate lyase family protein [KO:K01637] [EC:4.1.3.1 4.1.3.30]
I2456_26135  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
I2456_13420  malate synthase G [KO:K01638] [EC:2.3.3.9]
I2456_19805  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
I2456_22075  citrate synthase [KO:K01647] [EC:2.3.3.1]
I2456_22090  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
I2456_11260  aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
I2456_02865  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_13540  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_19125  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_19275  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_20770  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_21700  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_21955  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_22260  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_23775  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_25430  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
I2456_25555  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
I2456_25610  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
I2456_19280  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
I2456_06325  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
I2456_06355  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
I2456_06350  acyl-CoA carboxylase subunit epsilon [KO:K27095]
I2456_16065  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
I2456_11410  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
I2456_11415  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
I2456_22965  cobalamin-dependent protein [KO:K01849] [EC:5.4.99.2]
I2456_22970  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
I2456_07080  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
I2456_19730  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
I2456_00790  catalase [KO:K03781] [EC:1.11.1.6]
I2456_01360  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
I2456_26550  catalase [KO:K03781] [EC:1.11.1.6]
I2456_15865  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
I2456_07345  glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
I2456_09300  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
I2456_13645  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
I2456_14275  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
I2456_15770  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
I2456_15805  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
I2456_20680  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
I2456_13405  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
I2456_15705  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
I2456_04070  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
I2456_13380  gcvH; glycine cleavage system protein GcvH [KO:K02437]
I2456_07065  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
I2456_07075  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
I2456_07070  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
I2456_07090  glycerate kinase [KO:K00865] [EC:2.7.1.165]
I2456_15675  glycerate kinase [KO:K00865] [EC:2.7.1.165]
I2456_19790  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
I2456_15370  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
I2456_15375  4Fe-4S dicluster domain-containing protein [KO:K00124]
I2456_01800  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mku00010  Glycolysis / Gluconeogenesis
mku00020  Citrate cycle (TCA cycle)
mku00030  Pentose phosphate pathway
mku00053  Ascorbate and aldarate metabolism
mku00071  Fatty acid degradation
mku00230  Purine metabolism
mku00250  Alanine, aspartate and glutamate metabolism
mku00260  Glycine, serine and threonine metabolism
mku00620  Pyruvate metabolism
mku00710  Carbon fixation by Calvin cycle
mku00750  Vitamin B6 metabolism
mku00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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