KEGG   PATHWAY: msc00630
Entry
msc00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Methylocystis sp. SC2
Class
Metabolism; Carbohydrate metabolism
Pathway map
msc00630  Glyoxylate and dicarboxylate metabolism
msc00630

Module
msc_M00621  Glycine cleavage system [PATH:msc00630]
msc_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:msc00630]
Other DBs
GO: 0046487 0043648
Organism
Methylocystis sp. SC2 [GN:msc]
Gene
BN69_2196  acsA; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
BN69_1515  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BN69_0037  Citrate synthase [KO:K01647] [EC:2.3.3.1]
BN69_2108  acnA; Aconitate hydratase 1 (Aconitase 1) [KO:K01681] [EC:4.2.1.3]
BN69_1173  Succinyl-CoA ligase [KO:K08692] [EC:6.2.1.9]
BN69_1174  sucC1; Succinyl-CoA synthetase subunit beta [KO:K14067] [EC:6.2.1.9]
BN69_1000  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN69_3068  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN69_3358  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN69_3067  Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BN69_2149  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
BN69_1948  Crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
BN69_1209  Methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
BN69_1950  Methylmalonyl-CoA mutase, large subunit [KO:K14447] [EC:5.4.99.63]
BN69_1942  Acyl-CoA dehydrogenase domain-containing protein [KO:K14448] [EC:1.3.8.12]
BN69_0351  MaoC domain protein dehydratase [KO:K14449] [EC:4.2.1.148]
BN69_1171  Citryl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
BN69_2035  HpcH/HpaI aldolase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
BN69_3198  Carbamoyl-phosphate synthase L chain ATP-binding [KO:K01965] [EC:6.4.1.3]
BN69_0774  Carboxyl transferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
BN69_0753  Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
BN69_3344  Methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
BN69_0838  D-lactate dehydrogenase (Cytochrome) [KO:K00104] [EC:1.1.99.14]
BN69_0837  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
BN69_0836  Glycolate oxidase, iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BN69_2315  Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
BN69_1177  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding [KO:K00018] [EC:1.1.1.29]
BN69_1194  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BN69_1178  Aminotransferase class V [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
BN69_3582  Glutamate synthase [NADH], amyloplastic [KO:K00284] [EC:1.4.7.1]
BN69_0652  Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BN69_0473  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BN69_3656  Glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BN69_2039  gcvPA; Glycine cleavage system P-protein subunit 1/Glycine decarboxylase subunit 1 [KO:K00282] [EC:1.4.4.2]
BN69_2040  Glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
BN69_2037  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
BN69_0961  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BN69_2982  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BN69_2038  gcvH; Glycine cleavage system H protein [KO:K02437]
BN69_1168  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
BN69_2033  Putative oxalate decarboxylase family protein [KO:K01569] [EC:4.1.1.2]
BN69_1448  NAD-dependent formate dehydrogenase, delta subunit [KO:K00126] [EC:1.17.1.9]
BN69_1450  NAD-dependent formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BN69_1451  NADH dehydrogenase (Quinone) [KO:K00124]
BN69_1452  NADH dehydrogenase (Ubiquinone), 24 kDa subunit [KO:K00127]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
msc00010  Glycolysis / Gluconeogenesis
msc00020  Citrate cycle (TCA cycle)
msc00030  Pentose phosphate pathway
msc00053  Ascorbate and aldarate metabolism
msc00071  Fatty acid degradation
msc00230  Purine metabolism
msc00250  Alanine, aspartate and glutamate metabolism
msc00260  Glycine, serine and threonine metabolism
msc00620  Pyruvate metabolism
msc00710  Carbon fixation by Calvin cycle
msc00750  Vitamin B6 metabolism
msc00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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