KEGG   PATHWAY: nara00630
Entry
nara00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Natrialbaceae archaeon AArc-T1-2
Class
Metabolism; Carbohydrate metabolism
Pathway map
nara00630  Glyoxylate and dicarboxylate metabolism
nara00630

Module
nara_M00621  Glycine cleavage system [PATH:nara00630]
nara_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:nara00630]
nara_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:nara00630]
Other DBs
GO: 0046487 0043648
Organism
Natrialbaceae archaeon AArc-T1-2 [GN:nara]
Gene
QQ977_00205  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
QQ977_04075  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
QQ977_04085  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
QQ977_04300  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
QQ977_05520  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
QQ977_10670  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
QQ977_15130  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
QQ977_16500  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
QQ977_08010  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
QQ977_07870  citZ; citrate synthase [KO:K01647] [EC:2.3.3.1]
QQ977_09315  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
QQ977_15755  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
QQ977_00755  thiolase family protein [KO:K00626] [EC:2.3.1.9]
QQ977_06570  thiolase family protein [KO:K00626] [EC:2.3.1.9]
QQ977_15030  thiolase family protein [KO:K00626] [EC:2.3.1.9]
QQ977_15040  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
QQ977_08880  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
QQ977_16455  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
QQ977_13335  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
QQ977_05695  mch; 2-methylfumaryl-CoA hydratase [KO:K14449] [EC:4.2.1.148]
QQ977_05530  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
QQ977_11065  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
QQ977_01560  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
QQ977_05490  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
QQ977_01565  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
QQ977_05535  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
QQ977_08855  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
QQ977_05480  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
QQ977_10675  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
QQ977_13605  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
QQ977_05685  methylaspartate mutase subunit E [KO:K19268] [EC:5.4.99.1]
QQ977_05680  glmS; methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
QQ977_07090  glmS; methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
QQ977_08530  glmS; methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
QQ977_05690  methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
QQ977_05675  mct; succinyl-CoA:mesaconate CoA-transferase [KO:K19280] [EC:2.8.3.26]
QQ977_05700  citE; L-malyl-CoA/beta-methylmalyl-CoA lyase [KO:K19281] [EC:4.1.3.24]
QQ977_05745  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
QQ977_09985  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
QQ977_00075  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
QQ977_11555  rbcL; type III ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
QQ977_13695  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
QQ977_09830  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
QQ977_00060  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
QQ977_07950  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
QQ977_00795  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
QQ977_14530  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
QQ977_14525  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
QQ977_11195  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
QQ977_11335  aminomethyltransferase family protein [KO:K00605] [EC:2.1.2.10]
QQ977_06105  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
QQ977_11200  gcvH; glycine cleavage system protein GcvH [KO:K02437]
QQ977_05460  NAD(P)-binding domain-containing protein [KO:K00042] [EC:1.1.1.60]
QQ977_02580  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
QQ977_14560  glycerol dehydrogenase [KO:K26209] [EC:1.1.1.-]
QQ977_13385  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
QQ977_13390  4Fe-4S dicluster domain-containing protein [KO:K00124]
QQ977_14240  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
QQ977_15970  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
nara00010  Glycolysis / Gluconeogenesis
nara00020  Citrate cycle (TCA cycle)
nara00030  Pentose phosphate pathway
nara00053  Ascorbate and aldarate metabolism
nara00071  Fatty acid degradation
nara00230  Purine metabolism
nara00250  Alanine, aspartate and glutamate metabolism
nara00260  Glycine, serine and threonine metabolism
nara00620  Pyruvate metabolism
nara00710  Carbon fixation by Calvin cycle
nara00750  Vitamin B6 metabolism
nara00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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