KEGG   PATHWAY: nph00630
Entry
nph00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Natronomonas pharaonis
Class
Metabolism; Carbohydrate metabolism
Pathway map
nph00630  Glyoxylate and dicarboxylate metabolism
nph00630

Module
nph_M00012  Glyoxylate cycle [PATH:nph00630]
nph_M00621  Glycine cleavage system [PATH:nph00630]
nph_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:nph00630]
nph_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:nph00630]
Other DBs
GO: 0046487 0043648
Organism
Natronomonas pharaonis [GN:nph]
Gene
NP_4432A  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
NP_4240A  acs1; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
NP_4242A  acs2; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
NP_5128A  acs3; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
NP_0164A  acs5; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
NP_5132A  acs4; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
NP_0498A  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NP_1314A  citZ; citrate synthase [KO:K01647] [EC:2.3.3.1]
NP_1994A  citB2; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
NP_0404A  citB1; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
NP_2214A  acaB8; acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NP_3650A  acaB7; acetyl-CoA C-acetyltransferase catalytic subunit [KO:K00626] [EC:2.3.1.9]
NP_2606A  acaB1; acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NP_3420A  acaB3; acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NP_3438A  acaB4; acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NP_1228A  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
NP_4368A  pccA2; propionyl-CoA carboxylase biotin carboxylase component [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
NP_4252A  pccA1; propionyl-CoA carboxylase biotin carboxylase component [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
NP_4364A  pccB2; propionyl-CoA carboxylase carboxyltransferase component [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
NP_4366A  pccX; propionyl-CoA carboxylase small subunit [KO:K22568] [EC:6.4.1.2 6.4.1.3]
NP_2710A  mmcB; methylmalonyl-CoA mutase subunit B (cobalamin-binding subunit) [KO:K01849] [EC:5.4.99.2]
NP_2320A  mmcA1; methylmalonyl-CoA mutase subunit A [KO:K01848] [EC:5.4.99.2]
NP_1226A  mmcA2; methylmalonyl-CoA mutase subunit A [KO:K01848] [EC:5.4.99.2]
NP_4430A  aceB; malate synthase [KO:K19282] [EC:4.1.3.24 3.1.2.30]
NP_1762A  HAD superfamily hydrolase [KO:K01091] [EC:3.1.3.18]
NP_1738A  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
NP_2770A  rbcL; ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
NP_2578A  pyridoxal phosphate-dependent aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
NP_1794A  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
NP_4376A  glnA2; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
NP_0076A  glnA1; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
NP_2050A  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NP_4596A  gcvP1; glycine cleavage system protein P alpha subunit [KO:K00282] [EC:1.4.4.2]
NP_4594A  gcvP2; glycine cleavage system protein P beta subunit [KO:K00283] [EC:1.4.4.2]
NP_0436A  gcvT2; homolog to glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
NP_4774A  gcvT1; glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
NP_0104A  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NP_4772A  gcvH; glycine cleavage system protein H [KO:K02437]
NP_1162A  DUF4147 domain protein [KO:K11529] [EC:2.7.1.165]
NP_4962A  probable anaerobic dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
NP_4960A  probable anaerobic dehydrogenase iron-sulfur-binding subunit [KO:K00124]
NP_5006A  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
NP_6204A  fmdA; formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
nph00010  Glycolysis / Gluconeogenesis
nph00020  Citrate cycle (TCA cycle)
nph00030  Pentose phosphate pathway
nph00053  Ascorbate and aldarate metabolism
nph00071  Fatty acid degradation
nph00230  Purine metabolism
nph00250  Alanine, aspartate and glutamate metabolism
nph00260  Glycine, serine and threonine metabolism
nph00620  Pyruvate metabolism
nph00710  Carbon fixation by Calvin cycle
nph00750  Vitamin B6 metabolism
nph00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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