KEGG   PATHWAY: npl00630
Entry
npl00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Natrinema pallidum
Class
Metabolism; Carbohydrate metabolism
Pathway map
npl00630  Glyoxylate and dicarboxylate metabolism
npl00630

Module
npl_M00621  Glycine cleavage system [PATH:npl00630]
npl_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:npl00630]
npl_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:npl00630]
Other DBs
GO: 0046487 0043648
Organism
Natrinema pallidum [GN:npl]
Gene
FGF80_14300  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
FGF80_18095  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
FGF80_18125  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
FGF80_18170  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
FGF80_12020  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
FGF80_12030  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
FGF80_05565  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
FGF80_17185  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
FGF80_06945  citrate synthase [KO:K01647] [EC:2.3.3.1]
FGF80_07980  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
FGF80_11335  thiolase family protein [KO:K00626] [EC:2.3.1.9]
FGF80_11345  thiolase family protein [KO:K00626] [EC:2.3.1.9]
FGF80_01810  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
FGF80_13055  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
FGF80_12190  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
FGF80_04760  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
FGF80_03550  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
FGF80_10925  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
FGF80_11240  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
FGF80_18115  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
FGF80_11225  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
FGF80_11230  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
FGF80_13080  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
FGF80_03540  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
FGF80_18175  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
FGF80_10935  methylaspartate mutase subunit E [KO:K19268] [EC:5.4.99.1]
FGF80_06750  methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
FGF80_10940  methylaspartate mutase subunit S [KO:K01846] [EC:5.4.99.1]
FGF80_10930  methylaspartate ammonia-lyase [KO:K04835] [EC:4.3.1.2]
FGF80_10945  CoA transferase [KO:K19280] [EC:2.8.3.26]
FGF80_10920  citrate lyase subunit beta [KO:K19281] [EC:4.1.3.24]
FGF80_03080  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
FGF80_07760  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
FGF80_06680  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
FGF80_03510  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
FGF80_08395  HAD-IIB family hydrolase [KO:K22223] [EC:3.1.3.18]
FGF80_02615  rbcL; type III ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
FGF80_09750  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
FGF80_08195  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
FGF80_09305  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
FGF80_05400  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
FGF80_11400  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
FGF80_02770  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
FGF80_02775  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
FGF80_09340  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
FGF80_02700  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
FGF80_01580  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
FGF80_02695  gcvH; glycine cleavage system protein GcvH [KO:K02437]
FGF80_14715  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
FGF80_03730  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
FGF80_13820  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
npl00010  Glycolysis / Gluconeogenesis
npl00020  Citrate cycle (TCA cycle)
npl00030  Pentose phosphate pathway
npl00053  Ascorbate and aldarate metabolism
npl00071  Fatty acid degradation
npl00230  Purine metabolism
npl00250  Alanine, aspartate and glutamate metabolism
npl00260  Glycine, serine and threonine metabolism
npl00620  Pyruvate metabolism
npl00710  Carbon fixation by Calvin cycle
npl00750  Vitamin B6 metabolism
npl00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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