KEGG   PATHWAY: otw00630
Entry
otw00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Oncorhynchus tshawytscha (Chinook salmon)
Class
Metabolism; Carbohydrate metabolism
Pathway map
otw00630  Glyoxylate and dicarboxylate metabolism
otw00630

Module
otw_M00621  Glycine cleavage system [PATH:otw00630]
otw_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:otw00630]
Other DBs
GO: 0046487 0043648
Organism
Oncorhynchus tshawytscha (Chinook salmon) [GN:otw]
Gene
112215859  acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
112252906  acss1; acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
112222092  acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
112238361  LOW QUALITY PROTEIN: acetyl-coenzyme A synthetase, cytoplasmic [KO:K01895] [EC:6.2.1.1]
112236688  acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1 [KO:K01895] [EC:6.2.1.1]
112244522  acetyl-coenzyme A synthetase, cytoplasmic-like isoform X1 [KO:K01895] [EC:6.2.1.1]
112230370  mdh1aa; malate dehydrogenase, cytoplasmic isoform X1 [KO:K00025] [EC:1.1.1.37]
112240818  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
112265263  malate dehydrogenase, cytoplasmic-like isoform X1 [KO:K00025] [EC:1.1.1.37]
112228522  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
112257927  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
112221841  citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
112254744  citrate synthase, mitochondrial isoform X1 [KO:K01647] [EC:2.3.3.1]
112216248  citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
112226135  aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
112258805  aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
112258617  aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
112214712  aco1; cytoplasmic aconitate hydratase [KO:K01681] [EC:4.2.1.3]
112224397  aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
112217796  acat2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
112228596  acat1; acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
112249131  mcee; methylmalonyl-CoA epimerase, mitochondrial isoform X2 [KO:K05606] [EC:5.1.99.1]
112235776  methylmalonyl-CoA epimerase, mitochondrial-like [KO:K05606] [EC:5.1.99.1]
112267650  pcca; propionyl-CoA carboxylase alpha chain, mitochondrial [KO:K01965] [EC:6.4.1.3]
112240046  propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
112242452  propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
112232961  methylmalonyl-CoA mutase, mitochondrial-like isoform X1 [KO:K01847] [EC:5.4.99.2]
112245914  hydroxyacid oxidase 2 isoform X1 [KO:K11517] [EC:1.1.3.15]
112225478  hydroxyacid oxidase 2 isoform X1 [KO:K11517] [EC:1.1.3.15]
112232920  hao1; hydroxyacid oxidase 1 isoform X1 [KO:K11517] [EC:1.1.3.15]
112218377  cat; catalase isoform X1 [KO:K03781] [EC:1.11.1.6]
112230404  catalase [KO:K03781] [EC:1.11.1.6]
112265579  catalase [KO:K03781] [EC:1.11.1.6]
112256143  glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
112220833  glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
121842773  glyoxylate reductase/hydroxypyruvate reductase-like [KO:K00049] [EC:1.1.1.79 1.1.1.81]
121845029  glyoxylate reductase/hydroxypyruvate reductase-like [KO:K00049] [EC:1.1.1.79 1.1.1.81]
112224436  glycerol-3-phosphate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
112260179  agxtb; serine--pyruvate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
112236276  agxta; alanine--glyoxylate and serine--pyruvate aminotransferase a isoform X1 [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
112226869  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
112249886  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
112219351  glutamine synthetase isoform X1 [KO:K01915] [EC:6.3.1.2]
112260541  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
112251195  glulb; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
112221921  shmt2; serine hydroxymethyltransferase, mitochondrial isoform X1 [KO:K00600] [EC:2.1.2.1]
112240640  LOW QUALITY PROTEIN: serine hydroxymethyltransferase, cytosolic-like [KO:K00600] [EC:2.1.2.1]
112260818  serine hydroxymethyltransferase, cytosolic-like [KO:K00600] [EC:2.1.2.1]
112263127  glycine dehydrogenase (decarboxylating), mitochondrial isoform X1 [KO:K00281] [EC:1.4.4.2]
112232820  glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
112222113  aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
112221332  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
112218211  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
112249163  glycine cleavage system H protein, mitochondrial [KO:K02437]
112252449  glycine cleavage system H protein, mitochondrial [KO:K02437]
112263693  gcshb; glycine cleavage system H protein, mitochondrial [KO:K02437]
112218619  gcsha; glycine cleavage system protein H (aminomethyl carrier), a [KO:K02437]
112251274  hyi; putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
112247312  glyctk; glycerate kinase isoform X1 [KO:K11529] [EC:2.7.1.165]
112230192  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
112241666  afmid; kynurenine formamidase isoform X1 [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
otw00010  Glycolysis / Gluconeogenesis
otw00020  Citrate cycle (TCA cycle)
otw00030  Pentose phosphate pathway
otw00053  Ascorbate and aldarate metabolism
otw00071  Fatty acid degradation
otw00230  Purine metabolism
otw00250  Alanine, aspartate and glutamate metabolism
otw00260  Glycine, serine and threonine metabolism
otw00620  Pyruvate metabolism
otw00750  Vitamin B6 metabolism
otw00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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