KEGG   PATHWAY: paqt00630
Entry
paqt00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Phreatobacter aquaticus
Class
Metabolism; Carbohydrate metabolism
Pathway map
paqt00630  Glyoxylate and dicarboxylate metabolism
paqt00630

Module
paqt_M00621  Glycine cleavage system [PATH:paqt00630]
paqt_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:paqt00630]
Other DBs
GO: 0046487 0043648
Organism
Phreatobacter aquaticus [GN:paqt]
Gene
E8L99_05460  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
E8L99_11420  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
E8L99_11560  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
E8L99_09445  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
E8L99_11005  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
E8L99_17905  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
E8L99_23315  citrate synthase [KO:K01647] [EC:2.3.3.1]
E8L99_23320  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
E8L99_03795  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
E8L99_03725  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
E8L99_05180  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
E8L99_06000  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
E8L99_07110  thiolase family protein [KO:K00626] [EC:2.3.1.9]
E8L99_07355  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
E8L99_08195  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
E8L99_08445  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
E8L99_22955  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
E8L99_03720  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
E8L99_09805  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
E8L99_11590  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
E8L99_18880  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
E8L99_11580  protein meaA [KO:K14447] [EC:5.4.99.63]
E8L99_03210  acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
E8L99_10920  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
E8L99_17855  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
E8L99_19295  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
E8L99_16025  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
E8L99_19520  biotin carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
E8L99_12725  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
E8L99_12730  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
E8L99_04975  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
E8L99_04970  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
E8L99_04965  4Fe-4S dicluster domain-containing protein [KO:K11473] [EC:1.1.99.14]
E8L99_02775  catalase [KO:K03781] [EC:1.11.1.6]
E8L99_04955  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
E8L99_01525  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
E8L99_08830  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
E8L99_11990  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
E8L99_13985  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
E8L99_16005  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
E8L99_17980  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
E8L99_12595  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
E8L99_12835  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
E8L99_01140  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
E8L99_19060  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
E8L99_14280  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
E8L99_13455  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
E8L99_13460  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
E8L99_13445  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
E8L99_10965  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
E8L99_17490  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
E8L99_13450  gcvH; glycine cleavage system protein GcvH [KO:K02437]
E8L99_08325  glycerate kinase [KO:K11529] [EC:2.7.1.165]
E8L99_08290  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
E8L99_08295  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
E8L99_02310  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
E8L99_14915  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
E8L99_14920  4Fe-4S dicluster domain-containing protein [KO:K00124]
E8L99_14925  formate dehydrogenase subunit gamma [KO:K00127]
E8L99_13265  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
E8L99_17600  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
E8L99_01325  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
paqt00010  Glycolysis / Gluconeogenesis
paqt00020  Citrate cycle (TCA cycle)
paqt00030  Pentose phosphate pathway
paqt00053  Ascorbate and aldarate metabolism
paqt00071  Fatty acid degradation
paqt00230  Purine metabolism
paqt00250  Alanine, aspartate and glutamate metabolism
paqt00260  Glycine, serine and threonine metabolism
paqt00620  Pyruvate metabolism
paqt00710  Carbon fixation by Calvin cycle
paqt00750  Vitamin B6 metabolism
paqt00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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