KEGG   PATHWAY: pdx00630
Entry
pdx00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudonocardia dioxanivorans
Class
Metabolism; Carbohydrate metabolism
Pathway map
pdx00630  Glyoxylate and dicarboxylate metabolism
pdx00630

Module
pdx_M00621  Glycine cleavage system [PATH:pdx00630]
pdx_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:pdx00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudonocardia dioxanivorans [GN:pdx]
Gene
Psed_2717  Butyrate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Psed_0407  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Psed_4795  Acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Psed_4782  Malate synthase [KO:K01638] [EC:2.3.3.9]
Psed_2085  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Psed_2875  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Psed_0610  Citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
Psed_0613  citrate synthase I [KO:K01647] [EC:2.3.3.1]
Psed_6532  citrate synthase [KO:K01647] [EC:2.3.3.1]
Psed_3377  aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
Psed_1715  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_6174  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_0648  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_6148  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_0932  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_3737  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_6777  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_0260  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_5916  Acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Psed_1714  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Psed_1691  methylmalonyl-CoA mutase, large subunit [KO:K14447] [EC:5.4.99.63]
Psed_5269  Biotin carboxylase., Pyruvate carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
Psed_5275  Carbamoyl-phosphate synthase L chain ATP-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
Psed_5261  Propionyl-CoA carboxylase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
Psed_5262  hypothetical protein [KO:K27095]
Psed_0517  Propionyl-CoA carboxylase [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Psed_3124  Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Psed_3125  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
Psed_4783  D-lactate dehydrogenase (cytochrome) [KO:K00104] [EC:1.1.99.14]
Psed_4788  D-lactate dehydrogenase (cytochrome) [KO:K00104] [EC:1.1.99.14]
Psed_2201  D-lactate dehydrogenase (cytochrome) [KO:K00104] [EC:1.1.99.14]
Psed_5022  D-lactate dehydrogenase (cytochrome) [KO:K00104] [EC:1.1.99.14]
Psed_4784  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Psed_4789  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Psed_4785  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Psed_4790  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Psed_4106  Catalase [KO:K03781] [EC:1.11.1.6]
Psed_2743  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Psed_2092  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Psed_2947  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Psed_6249  Ribulose bisphosphate carboxylase large chain [KO:K01601] [EC:4.1.1.39]
Psed_6250  Ribulose-bisphosphate carboxylase [KO:K01602] [EC:4.1.1.39]
Psed_1785  Serine--pyruvate transaminase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Psed_2546  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Psed_3968  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Psed_4917  glutamine synthetase, type III [KO:K01915] [EC:6.3.1.2]
Psed_4574  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Psed_1674  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Psed_2550  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Psed_2553  Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
Psed_3163  Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
Psed_2552  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Psed_3378  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Psed_3308  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Psed_4565  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Psed_6230  Glycine cleavage system H protein [KO:K02437]
Psed_2551  Glycine cleavage system H protein [KO:K02437]
Psed_5580  Glycine cleavage system H protein [KO:K02437]
Psed_3890  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
Psed_4949  Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Psed_3888  Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Psed_3889  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Psed_4556  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Psed_3891  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Psed_0695  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Psed_5115  2-oxoglutarate dehydrogenase, E1 subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Psed_3044  hypothetical protein [KO:K00126] [EC:1.17.1.9]
Psed_2418  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Psed_3043  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Psed_2417  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein [KO:K00124]
Psed_3042  NADH dehydrogenase (quinone) [KO:K00124]
Psed_3041  NADH dehydrogenase (ubiquinone) 24 kDa subunit [KO:K00127]
Psed_0593  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Psed_2100  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Psed_4922  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Psed_3049  Formamidase [KO:K01455] [EC:3.5.1.49]
Psed_3799  Formamidase [KO:K01455] [EC:3.5.1.49]
Psed_4884  Formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pdx00010  Glycolysis / Gluconeogenesis
pdx00020  Citrate cycle (TCA cycle)
pdx00030  Pentose phosphate pathway
pdx00053  Ascorbate and aldarate metabolism
pdx00071  Fatty acid degradation
pdx00230  Purine metabolism
pdx00250  Alanine, aspartate and glutamate metabolism
pdx00260  Glycine, serine and threonine metabolism
pdx00620  Pyruvate metabolism
pdx00710  Carbon fixation by Calvin cycle
pdx00750  Vitamin B6 metabolism
pdx00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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