KEGG   PATHWAY: ppf00362
Entry
ppf00362                    Pathway                                
Name
Benzoate degradation - Pseudomonas putida F1
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
ppf00362  Benzoate degradation
ppf00362

Module
ppf_M00547  Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol [PATH:ppf00362]
ppf_M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:ppf00362]
ppf_M00568  Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:ppf00362]
Other DBs
UMBBD: benz2 benz abs
GO: 0043639
Organism
Pseudomonas putida F1 [GN:ppf]
Gene
Pput_2554  benzoate 1,2-dioxygenase, alpha subunit [KO:K05549] [EC:1.14.12.10 1.14.12.-]
Pput_2553  benzoate 1,2-dioxygenase, beta subunit [KO:K05550] [EC:1.14.12.10 1.14.12.-]
Pput_2552  oxidoreductase FAD/NAD(P)-binding domain protein [KO:K05784] [EC:1.18.1.-]
Pput_2551  1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase [KO:K05783] [EC:1.3.1.25 1.3.1.-]
Pput_2549  catechol 1,2-dioxygenase [KO:K03381] [EC:1.13.11.1]
Pput_2055  catechol 1,2-dioxygenase [KO:K03381] [EC:1.13.11.1]
Pput_2053  muconate cycloisomerase [KO:K01856] [EC:5.5.1.1]
Pput_2054  muconolactone delta-isomerase [KO:K03464] [EC:5.3.3.4]
Pput_4343  3-oxoadipate enol-lactonase [KO:K01055] [EC:3.1.1.24]
Pput_1350  alpha/beta hydrolase fold protein [KO:K01055] [EC:3.1.1.24]
Pput_1871  3-oxoadipate CoA-transferase alpha subunit [KO:K01031] [EC:2.8.3.6]
Pput_5289  3-oxoadipate CoA-transferase alpha subunit [KO:K01031] [EC:2.8.3.6]
Pput_1870  3-oxoadipate CoA-transferase beta subunit [KO:K01032] [EC:2.8.3.6]
Pput_5290  butyryl-CoA:acetate CoA transferase [KO:K01032] [EC:2.8.3.6]
Pput_3605  3-ketoacyl-CoA thiolase [KO:K00632] [EC:2.3.1.16]
Pput_4346  beta-ketoadipyl CoA thiolase [KO:K07823] [EC:2.3.1.174]
Pput_2479  beta-ketoadipyl CoA thiolase [KO:K07823] [EC:2.3.1.174]
Pput_2881  ring hydroxylating dioxygenase, alpha subunit [KO:K03268] [EC:1.14.12.3 1.14.12.11 1.14.12.26]
Pput_2880  Toluene dioxygenase [KO:K16268] [EC:1.14.12.3 1.14.12.11 1.14.12.26]
Pput_2879  Rieske (2Fe-2S) domain protein [KO:K18089]
Pput_2878  FAD-dependent pyridine nucleotide-disulfide oxidoreductase [KO:K18090] [EC:1.18.1.3 1.18.1.-]
Pput_2877  short-chain dehydrogenase/reductase SDR [KO:K16269] [EC:1.3.1.19 1.3.1.119]
Pput_2896  Glyoxalase/bleomycin resistance protein/dioxygenase [KO:K10621] [EC:1.13.11.- 1.13.11.14]
Pput_2893  class II aldolase/adducin family protein [KO:K10622] [EC:4.1.1.-]
Pput_2890  4-oxalocrotonate decarboxylase [KO:K02554] [EC:4.2.1.80]
Pput_2875  4-oxalocrotonate decarboxylase [KO:K02554] [EC:4.2.1.80]
Pput_2159  Hydratase/decarboxylase [KO:K02554] [EC:4.2.1.80]
Pput_2873  4-hydroxy-2-oxovalerate aldolase [KO:K01666] [EC:4.1.3.39]
Pput_2888  pyruvate carboxyltransferase [KO:K01666] [EC:4.1.3.39]
Pput_2874  acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
Pput_2889  acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
Pput_4517  protocatechuate 3,4-dioxygenase, alpha subunit [KO:K00448] [EC:1.13.11.3]
Pput_4518  protocatechuate 3,4-dioxygenase, beta subunit [KO:K00449] [EC:1.13.11.3]
Pput_4344  3-carboxy-cis,cis-muconate cycloisomerase [KO:K01857] [EC:5.5.1.2]
Pput_2082  4-carboxymuconolactone decarboxylase [KO:K01607] [EC:4.1.1.44]
Pput_4342  4-carboxymuconolactone decarboxylase [KO:K01607] [EC:4.1.1.44]
Pput_1365  amidohydrolase 2 [KO:K10221] [EC:3.1.1.57]
Pput_1360  methylitaconate delta2-delta3-isomerase [KO:K16514] [EC:5.3.2.8]
Pput_3205  methylitaconate delta2-delta3-isomerase [KO:K16514] [EC:5.3.2.8]
Pput_1362  LmbE family protein [KO:K16515] [EC:4.2.1.83]
Pput_3203  LmbE family protein [KO:K16515] [EC:4.2.1.83]
Pput_1361  4-carboxy-4-hydroxy-2-oxoadipate aldolase [KO:K10218] [EC:4.1.3.17]
Pput_3204  4-carboxy-4-hydroxy-2-oxoadipate aldolase [KO:K10218] [EC:4.1.3.17]
Pput_0877  ferredoxin, 2Fe-2S type, ISC system [KO:K04755]
Pput_2237  4-hydroxybenzoate 3-monooxygenase [KO:K00481] [EC:1.14.13.2]
Pput_1247  Pol-Pal system-associated acyl-CoA thioesterase [KO:K01075] [EC:3.1.2.23]
Pput_3606  3-hydroxyacyl-CoA dehydrogenase [KO:K01825] [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
Pput_0177  acyl-CoA dehydrogenase domain protein [KO:K00252] [EC:1.3.8.6]
Pput_2475  short chain enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
Pput_3521  short chain enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
Pput_2008  3-hydroxyacyl-CoA dehydrogenase [KO:K00074] [EC:1.1.1.157]
Pput_2477  3-hydroxyacyl-CoA dehydrogenase [KO:K00074] [EC:1.1.1.157]
Pput_0621  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Pput_2009  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pput_3690  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pput_3523  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pput_4498  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pput_2403  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00036  Oxaloacetate
C00084  Acetaldehyde
C00090  Catechol
C00091  Succinyl-CoA
C00146  Phenol
C00156  4-Hydroxybenzoate
C00180  Benzoate
C00196  2,3-Dihydroxybenzoate
C00230  3,4-Dihydroxybenzoate
C00332  Acetoacetyl-CoA
C00512  Benzoyl-CoA
C00527  Glutaryl-CoA
C00530  Hydroquinone
C00587  3-Hydroxybenzoate
C00596  2-Hydroxy-2,4-pentadienoate
C00628  2,5-Dihydroxybenzoate
C00682  2-Hydroxymuconate semialdehyde
C00846  3-Oxoadipate
C00877  Crotonoyl-CoA
C01063  Pimeloyl-CoA
C01144  (S)-3-Hydroxybutanoyl-CoA
C01163  3-Carboxy-cis,cis-muconate
C01278  2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate
C01407  Benzene
C01751  Resorcinol
C02222  2-Maleylacetate
C02232  3-Oxoadipyl-CoA
C02411  Glutaconyl-1-CoA
C02480  cis,cis-Muconate
C02501  2-Hydroxymuconate
C02519  4-Methoxybenzoate
C02814  Benzene-1,2,4-triol
C02949  4-Hydroxybenzoyl-CoA
C03453  gamma-Oxalocrotonate
C03586  2-Oxo-2,3-dihydrofuran-5-acetate
C03589  4-Hydroxy-2-oxopentanoate
C03671  2-Pyrone-4,6-dicarboxylate
C03676  3-Hydroxy-cis,cis-muconate
C03767  4-Oxocyclohexanecarboxylate
C04091  cis-1,2-Dihydrobenzene-1,2-diol
C04115  4-Carboxy-4-hydroxy-2-oxoadipate
C04324  (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
C04404  trans-4-Hydroxycyclohexanecarboxylate
C04434  (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
C04480  3-Carboxy-2-hydroxymuconate semialdehyde
C04484  4-Carboxy-2-hydroxymuconate semialdehyde
C04553  3-Carboxy-2,5-dihydro-5-oxofuran-2-acetate
C05375  2-Hydroxy-2-hydropyrone-4,6-dicarboxylate
C06033  Parapyruvate
C06035  4-Methylene-2-oxoglutarate
C06321  (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate
C06322  Cyclohexa-1,5-diene-1-carbonyl-CoA
C06333  2-Aminobenzenesulfonate
C06336  3-Sulfocatechol
C06714  3-Hydroxypimeloyl-CoA
C06715  3-Oxopimeloyl-CoA
C06723  6-Carboxyhex-2-enoyl-CoA
C06749  6-Hydroxycyclohex-1-ene-1-carbonyl-CoA
C09809  Cyclohexa-2,5-diene-1-carbonyl-CoA
C09810  Cyclohexa-1,4-diene-1-carbonyl-CoA
C09811  Cyclohex-1-ene-1-carbonyl-CoA
C09812  2-Hydroxycyclohexane-1-carbonyl-CoA
C09813  2-Oxocyclohexane-1-carbonyl-CoA
C09821  6-Oxocyclohex-1-ene-1-carbonyl-CoA
C09822  Cyclohexane-1-carboxylate
C09823  Cyclohexane-1-carbonyl-CoA
C14144  5-Carboxy-2-pentenoyl-CoA
C14610  (S)-5-Oxo-2,5-dihydrofuran-2-acetate
C19682  3,4-Didehydroadipyl-CoA
C19683  3,4-Didehydroadipyl-CoA semialdehyde
C19684  2,3-Epoxy-2,3-dihydrobenzoyl-CoA
C21298  2,6-Dihydroxybenzoate
C22885  cis-4-Hydroxycyclohexane-1-carboxylate
C22887  4-Oxocyclohex-2-ene-1-carboxylate
C22920  4-Oxocyclohex-2,5-dienecarboxylate
Reference
  Authors
Carmona M, Zamarro MT, Blazquez B, Durante-Rodriguez G, Juarez JF, Valderrama JA, Barragan MJ, Garcia JL, Diaz E
  Title
Anaerobic catabolism of aromatic compounds: a genetic and genomic view.
  Journal
Microbiol Mol Biol Rev 73:71-133 (2009)
DOI:10.1128/MMBR.00021-08
Reference
  Authors
Hara H, Masai E, Miyauchi K, Katayama Y, Fukuda M.
  Title
Characterization of the 4-carboxy-4-hydroxy-2-oxoadipate aldolase gene and operon structure of the protocatechuate 4,5-cleavage pathway genes in Sphingomonas paucimobilis SYK-6.
  Journal
J Bacteriol 185:41-50 (2003)
DOI:10.1128/JB.185.1.41-50.2003
Reference
  Authors
Maruyama K, Shibayama T, Ichikawa A, Sakou Y, Yamada S, Sugisaki H.
  Title
Cloning and characterization of the genes encoding enzymes for the protocatechuate meta-degradation pathway of Pseudomonas ochraceae NGJ1.
  Journal
Biosci Biotechnol Biochem 68:1434-41 (2004)
DOI:10.1271/bbb.68.1434
Reference
  Authors
Mampel J, Ruff J, Junker F, Cook AM.
  Title
The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1.
  Journal
Microbiology 145 ( Pt 11):3255-64 (1999)
DOI:10.1099/00221287-145-11-3255
Reference
PMID:8002948
  Authors
Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM.
  Title
Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid.
  Journal
Biochem J 300 ( Pt 2):429-36 (1994)
DOI:10.1042/bj3000429
Reference
PMID:8990279
  Authors
Harwood CS, Gibson J.
  Title
Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?
  Journal
J Bacteriol 179:301-9 (1997)
DOI:10.1128/JB.179.2.301-309.1997
Reference
  Authors
Peters F, Shinoda Y, McInerney MJ, Boll M.
  Title
Cyclohexa-1,5-diene-1-carbonyl-coenzyme A (CoA) hydratases of Geobacter metallireducens and Syntrophus aciditrophicus: Evidence for a common benzoyl-CoA degradation pathway in facultative and strict anaerobes.
  Journal
J Bacteriol 189:1055-60 (2007)
DOI:10.1128/JB.01467-06
Reference
  Authors
Cowles CE, Nichols NN, Harwood CS.
  Title
BenR, a XylS homologue, regulates three different pathways of aromatic acid degradation in Pseudomonas putida.
  Journal
J Bacteriol 182:6339-46 (2000)
DOI:10.1128/JB.182.22.6339-6346.2000
Reference
  Authors
Smith MA, Weaver VB, Young DM, Ornston LN.
  Title
Genes for chlorogenate and hydroxycinnamate catabolism (hca) are linked to functionally related genes in the dca-pca-qui-pob-hca chromosomal cluster of Acinetobacter sp. strain ADP1.
  Journal
Appl Environ Microbiol 69:524-32 (2003)
DOI:10.1128/AEM.69.1.524-532.2003
Reference
  Authors
Kuntze K, Shinoda Y, Moutakki H, McInerney MJ, Vogt C, Richnow HH, Boll M
  Title
6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes.
  Journal
Environ Microbiol 10:1547-56 (2008)
DOI:10.1111/j.1462-2920.2008.01570.x
Reference
  Authors
Pelletier DA, Harwood CS
  Title
2-Hydroxycyclohexanecarboxyl coenzyme A dehydrogenase, an enzyme characteristic of the anaerobic benzoate degradation pathway used by Rhodopseudomonas palustris.
  Journal
J Bacteriol 182:2753-60 (2000)
DOI:10.1128/JB.182.10.2753-2760.2000
Reference
  Authors
Elshahed MS, Bhupathiraju VK, Wofford NQ, Nanny MA, McInerney MJ
  Title
Metabolism of benzoate, cyclohex-1-ene carboxylate, and cyclohexane carboxylate by "Syntrophus aciditrophicus" strain SB in syntrophic association with H(2)-using microorganisms.
  Journal
Appl Environ Microbiol 67:1728-38 (2001)
DOI:10.1128/AEM.67.4.1728-1738.2001
Reference
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
  Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
  Journal
Mol Microbiol 79:359-74 (2011)
DOI:10.1111/j.1365-2958.2010.07448.x
Related
pathway
ppf00010  Glycolysis / Gluconeogenesis
ppf00020  Citrate cycle (TCA cycle)
ppf00350  Tyrosine metabolism
ppf00360  Phenylalanine metabolism
ppf00361  Chlorocyclohexane and chlorobenzene degradation
ppf00627  Aminobenzoate degradation
ppf00790  Folate biosynthesis
KO pathway
ko00362   
LinkDB

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