KEGG   PATHWAY: rpt02024
Entry
rpt02024                    Pathway                                
Name
Quorum sensing - Rhodopseudomonas palustris TIE-1
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
rpt02024  Quorum sensing
rpt02024

Other DBs
GO: 0009372
Organism
Rhodopseudomonas palustris TIE-1 [GN:rpt]
Gene
Rpal_2867  RNA chaperone Hfq [KO:K03666]
Rpal_2197  phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
Rpal_0028  phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
Rpal_3592  phenazine biosynthesis protein PhzF family [KO:K06998] [EC:5.3.3.17]
Rpal_3409  two component transcriptional regulator, winged helix family [KO:K07667]
Rpal_0322  putative autoinducer (acylhomoserine lactone) synthase [KO:K18096] [EC:2.3.1.228 2.3.1.229 2.3.1.-]
Rpal_2331  autoinducer synthesis protein [KO:K18096] [EC:2.3.1.228 2.3.1.229 2.3.1.-]
Rpal_0323  transcriptional regulator, LuxR family [KO:K18098]
Rpal_2330  transcriptional regulator, LuxR family [KO:K18098]
Rpal_1847  putative rhizosphere induced protein [KO:K20270]
Rpal_5129  extracellular solute-binding protein family 1 [KO:K02055]
Rpal_1663  extracellular solute-binding protein family 1 [KO:K02055]
Rpal_1664  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Rpal_1665  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Rpal_5130  binding-protein-dependent transport systems inner membrane component [KO:K02053 K02054]
Rpal_1666  ABC transporter related [KO:K02052]
Rpal_5131  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Rpal_0110  putative ABC transporter; putative branched-chain amino acid transporter [KO:K01999]
Rpal_4244  Extracellular ligand-binding receptor [KO:K01999]
Rpal_4245  ABC transporter substrate-binding protein [KO:K01999]
Rpal_0486  substrate-binding protein [KO:K01999]
Rpal_2487  Extracellular ligand-binding receptor [KO:K01999]
Rpal_1177  Extracellular ligand-binding receptor [KO:K01999]
Rpal_0735  Extracellular ligand-binding receptor [KO:K01999]
Rpal_4549  Extracellular ligand-binding receptor [KO:K01999]
Rpal_4559  Extracellular ligand-binding receptor [KO:K01999]
Rpal_4564  extracellular ligand-binding receptor [KO:K01999]
Rpal_4575  ABC transporter substrate-binding protein [KO:K01999]
Rpal_2079  branched chain amino acid transport system substrate binding protein [KO:K01999]
Rpal_3503  putative ABC transporter, substrate binding protein [KO:K01999]
Rpal_1941  Extracellular ligand-binding receptor [KO:K01999]
Rpal_1948  Extracellular ligand-binding receptor [KO:K01999]
Rpal_4882  Extracellular ligand-binding receptor [KO:K01999]
Rpal_1850  putative ABC transporter, substrate binding protein [KO:K01999]
Rpal_4334  Extracellular ligand-binding receptor [KO:K01999]
Rpal_5300  putative periplasmic substrate binding protein [KO:K01999]
Rpal_1991  Extracellular ligand-binding receptor [KO:K01999]
Rpal_2248  Extracellular ligand-binding receptor [KO:K01999]
Rpal_2001  Extracellular ligand-binding receptor [KO:K01999]
Rpal_4000  Extracellular ligand-binding receptor [KO:K01999]
Rpal_1428  Extracellular ligand-binding receptor [KO:K01999]
Rpal_1559  Extracellular ligand-binding receptor [KO:K01999]
Rpal_4246  Extracellular ligand-binding receptor [KO:K01999]
Rpal_5294  putative ABC-type branched-chain amino acid transporter, periplasmic binding protein [KO:K01999]
Rpal_0583  Extracellular ligand-binding receptor [KO:K01999]
Rpal_1598  Extracellular ligand-binding receptor [KO:K01999]
Rpal_1842  conserved hypothetical protein [KO:K01999]
Rpal_3830  branched-chain amino acid ABC transporter, periplasmic binding protein, putative [KO:K01999]
Rpal_1752  putative UreA/short-chain amide transport system substrate-binding protein [KO:K01999]
Rpal_4650  putative ABC transporter (substrate-binding protein); putative branched-chain amino acid transporter [KO:K01999]
Rpal_3718  branched-chain amino acid ABC transporter, periplasmic binding protein, putative [KO:K01999]
Rpal_4242  inner-membrane translocator [KO:K01997]
Rpal_1423  inner-membrane translocator [KO:K01997]
Rpal_2519  inner-membrane translocator [KO:K01997]
Rpal_1178  inner-membrane translocator [KO:K01997]
Rpal_0734  inner-membrane translocator [KO:K01997]
Rpal_1753  inner-membrane translocator [KO:K01997]
Rpal_4550  inner-membrane translocator [KO:K01997]
Rpal_4558  inner-membrane translocator [KO:K01997]
Rpal_4565  inner-membrane translocator [KO:K01997]
Rpal_4573  inner-membrane translocator [KO:K01997]
Rpal_1940  inner-membrane translocator [KO:K01997]
Rpal_1949  inner-membrane translocator [KO:K01997]
Rpal_4885  inner-membrane translocator [KO:K01997]
Rpal_4330  inner-membrane translocator [KO:K01997]
Rpal_1995  inner-membrane translocator [KO:K01997]
Rpal_3829  inner-membrane translocator [KO:K01997]
Rpal_3717  inner-membrane translocator [KO:K01997]
Rpal_1555  inner-membrane translocator [KO:K01997]
Rpal_1601  inner-membrane translocator [KO:K01997]
Rpal_0733  ABC transporter related [KO:K01995 K01998]
Rpal_1754  ABC transporter related [KO:K01995 K01998]
Rpal_1994  ABC transporter related [KO:K01995 K01998]
Rpal_1556  inner-membrane translocator [KO:K01995 K01998]
Rpal_1602  inner-membrane translocator [KO:K01998]
Rpal_1424  inner-membrane translocator [KO:K01998]
Rpal_1179  inner-membrane translocator [KO:K01998]
Rpal_1939  inner-membrane translocator [KO:K01998]
Rpal_1950  inner-membrane translocator [KO:K01998]
Rpal_2520  inner-membrane translocator [KO:K01998]
Rpal_4331  inner-membrane translocator [KO:K01998]
Rpal_4243  inner-membrane translocator [KO:K01998]
Rpal_4551  inner-membrane translocator [KO:K01998]
Rpal_4557  inner-membrane translocator [KO:K01998]
Rpal_4566  inner-membrane translocator [KO:K01998]
Rpal_4574  inner-membrane translocator [KO:K01998]
Rpal_4886  inner-membrane translocator [KO:K01998]
Rpal_4240  ABC transporter related [KO:K01995]
Rpal_1425  ABC transporter related [KO:K01995]
Rpal_2517  ABC transporter related [KO:K01995]
Rpal_1180  ABC transporter related [KO:K01995]
Rpal_1599  ABC transporter related [KO:K01995]
Rpal_4552  ABC transporter related [KO:K01995]
Rpal_4556  ABC transporter related [KO:K01995]
Rpal_4567  ABC transporter related [KO:K01995]
Rpal_4571  ABC transporter related [KO:K01995]
Rpal_1951  ABC transporter related [KO:K01995]
Rpal_4883  ABC transporter related [KO:K01995]
Rpal_4332  ABC transporter related [KO:K01995]
Rpal_3715  ABC transporter related [KO:K01995]
Rpal_1557  ABC transporter related [KO:K01995]
Rpal_3827  ABC transporter related [KO:K01995]
Rpal_1558  ABC transporter related [KO:K01996]
Rpal_1426  ABC transporter related [KO:K01996]
Rpal_1755  ABC transporter related [KO:K01996]
Rpal_1600  ABC transporter related [KO:K01996]
Rpal_1181  ABC transporter related [KO:K01996]
Rpal_0732  ABC transporter related [KO:K01996]
Rpal_1952  ABC transporter related [KO:K01996]
Rpal_1993  ABC transporter related [KO:K01996]
Rpal_2518  ABC transporter related [KO:K01996]
Rpal_3826  ABC transporter related [KO:K01996]
Rpal_3714  ABC transporter related [KO:K01996]
Rpal_4333  ABC transporter related [KO:K01996]
Rpal_4241  ABC transporter related [KO:K01996]
Rpal_4576  ABC transporter related [KO:K01996]
Rpal_4553  ABC transporter related [KO:K01996]
Rpal_4555  ABC transporter related [KO:K01996]
Rpal_4568  ABC transporter related [KO:K01996]
Rpal_4884  ABC transporter related [KO:K01996]
Rpal_4746  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Rpal_4572  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Rpal_1967  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Rpal_4237  dicarboxylate/CoA ligase PimA [KO:K01897] [EC:6.2.1.3]
Rpal_1427  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Rpal_5310  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Rpal_2434  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Rpal_4908  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Rpal_1635  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Rpal_0148  response regulator receiver modulated metal dependent phosphohydrolase [KO:K13815]
Rpal_4520  transcriptional regulator, Crp/Fnr family [KO:K10914]
Rpal_4383  transcriptional regulator, Crp/Fnr family [KO:K10914]
Rpal_0518  ferric uptake regulator, Fur family [KO:K09823]
Rpal_3006  riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
Rpal_4297  efflux transporter, RND family, MFP subunit [KO:K18306]
Rpal_4296  acriflavin resistance protein [KO:K18307]
Rpal_2841  RND efflux system, outer membrane lipoprotein, NodT family [KO:K18139]
Rpal_1411  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_1660  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_2571  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_0833  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_0106  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_2941  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_2913  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_2918  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_1632  extracellular solute-binding protein family 5 [KO:K02035]
Rpal_0832  4-phytase [KO:K02035]
Rpal_1409  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Rpal_1633  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Rpal_2572  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Rpal_0831  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Rpal_2917  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Rpal_0105  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Rpal_1659  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Rpal_1408  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Rpal_1658  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Rpal_1634  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Rpal_2573  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Rpal_0830  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Rpal_2916  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Rpal_0104  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Rpal_1630  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02031]
Rpal_0826  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02031]
Rpal_0103  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02031]
Rpal_1407  ABC transporter related [KO:K02031 K02032]
Rpal_1656  ABC transporter related [KO:K02031 K02032]
Rpal_2574  ABC transporter related [KO:K02031 K02032]
Rpal_2915  ABC transporter related [KO:K02031 K02032]
Rpal_1631  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02032]
Rpal_0102  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02032]
Rpal_0829  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02032]
Rpal_0636  60 kDa inner membrane insertion protein [KO:K03217]
Rpal_3694  preprotein translocase, SecE subunit [KO:K03073]
Rpal_3232  preprotein translocase, SecG subunit [KO:K03075]
Rpal_3647  preprotein translocase, SecY subunit [KO:K03076]
Rpal_3173  preprotein translocase, YajC subunit [KO:K03210]
Rpal_0511  preprotein translocase, SecA subunit [KO:K03070] [EC:7.4.2.8]
Rpal_0207  signal recognition particle-docking protein FtsY [KO:K03110]
Rpal_0304  protein-export protein SecB [KO:K03071]
Rpal_0246  signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
PMID:25824838
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
  Journal
Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
Reference
PMID:19363118
  Authors
Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
  Title
Virulence gene regulation by the agr system in Clostridium perfringens.
  Journal
J Bacteriol 191:3919-27 (2009)
DOI:10.1128/JB.01455-08
Reference
PMID:22736963
  Authors
Li YH, Tian X
  Title
Quorum sensing and bacterial social interactions in biofilms.
  Journal
Sensors (Basel) 12:2519-38 (2012)
DOI:10.3390/s120302519
Reference
PMID:22407687
  Authors
Berg KH, Biornstad TJ, Johnsborg O, Havarstein LS
  Title
Properties and biological role of streptococcal fratricins.
  Journal
Appl Environ Microbiol 78:3515-22 (2012)
DOI:10.1128/AEM.00098-12
Reference
PMID:25475081
  Authors
Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP
  Title
Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
  Journal
J Oral Microbiol 6:26189 (2014)
DOI:10.3402/jom.v6.26189
Reference
PMID:25309879
  Authors
Jimenez JC, Federle MJ
  Title
Quorum sensing in group A Streptococcus.
  Journal
Front Cell Infect Microbiol 4:127 (2014)
DOI:10.3389/fcimb.2014.00127
Reference
PMID:24118108
  Authors
Cook LC, Federle MJ
  Title
Peptide pheromone signaling in Streptococcus and Enterococcus.
  Journal
FEMS Microbiol Rev 38:473-92 (2014)
DOI:10.1111/1574-6976.12046
Reference
PMID:9680220
  Authors
Podbielski A, Leonard BA
  Title
The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease.
  Journal
Mol Microbiol 28:1323-34 (1998)
DOI:10.1046/j.1365-2958.1998.00898.x
Reference
PMID:8885277
  Authors
Podbielski A, Pohl B, Woischnik M, Korner C, Schmidt KH, Rozdzinski E, Leonard BA
  Title
Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production.
  Journal
Mol Microbiol 21:1087-99 (1996)
DOI:10.1046/j.1365-2958.1996.661421.x
Reference
PMID:22636768
  Authors
Anbalagan S, Dmitriev A, McShan WM, Dunman PM, Chaussee MS
  Title
Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.
  Journal
J Bacteriol 194:3961-71 (2012)
DOI:10.1128/JB.06709-11
Reference
PMID:22016844
  Authors
Clewell DB
  Title
Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
  Journal
Mob Genet Elements 1:38-54 (2011)
DOI:10.4161/mge.1.1.15409
Reference
PMID:20734751
  Authors
Wardal E, Sadowy E, Hryniewicz W
  Title
Complex nature of enterococcal pheromone-responsive plasmids.
  Journal
Pol J Microbiol 59:79-87 (2010)
Reference
PMID:19683678
  Authors
Roux A, Payne SM, Gilmore MS
  Title
Microbial telesensing: probing the environment for friends, foes, and food.
  Journal
Cell Host Microbe 6:115-24 (2009)
DOI:10.1016/j.chom.2009.07.004
Reference
PMID:25089349
  Authors
Slamti L, Perchat S, Huillet E, Lereclus D
  Title
Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
  Journal
Toxins (Basel) 6:2239-55 (2014)
DOI:10.3390/toxins6082239
Reference
PMID:20030732
  Authors
Lopez D, Kolter R
  Title
Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis.
  Journal
FEMS Microbiol Rev 34:134-49 (2010)
DOI:10.1111/j.1574-6976.2009.00199.x
Reference
PMID:12897006
  Authors
Stephenson S, Mueller C, Jiang M, Perego M
  Title
Molecular analysis of Phr peptide processing in Bacillus subtilis.
  Journal
J Bacteriol 185:4861-71 (2003)
DOI:10.1128/JB.185.16.4861-4871.2003
Reference
PMID:17666034
  Authors
Lanigan-Gerdes S, Dooley AN, Faull KF, Lazazzera BA
  Title
Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
  Journal
Mol Microbiol 65:1321-33 (2007)
DOI:10.1111/j.1365-2958.2007.05869.x
Reference
PMID:15374644
  Authors
Kleerebezem M
  Title
Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis.
  Journal
Peptides 25:1405-14 (2004)
DOI:10.1016/j.peptides.2003.10.021
Reference
PMID:23125205
  Authors
Rutherford ST, Bassler BL
  Title
Bacterial quorum sensing: its role in virulence and possibilities for its control.
  Journal
Cold Spring Harb Perspect Med 2:a012427 (2012)
DOI:10.1101/cshperspect.a012427
Reference
PMID:23471618
  Authors
LaSarre B, Federle MJ
  Title
Exploiting quorum sensing to confuse bacterial pathogens.
  Journal
Microbiol Mol Biol Rev 77:73-111 (2013)
DOI:10.1128/MMBR.00046-12
Reference
PMID:18781869
  Authors
Sifri CD
  Title
Healthcare epidemiology: quorum sensing: bacteria talk sense.
  Journal
Clin Infect Dis 47:1070-6 (2008)
DOI:10.1086/592072
Related
pathway
rpt00405  Phenazine biosynthesis
rpt02040  Flagellar assembly
KO pathway
ko02024   
LinkDB

DBGET integrated database retrieval system