KEGG   PATHWAY: shp00280
Entry
shp00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Shewanella putrefaciens 200
Class
Metabolism; Amino acid metabolism
Pathway map
shp00280  Valine, leucine and isoleucine degradation
shp00280

Module
shp_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:shp00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Shewanella putrefaciens 200 [GN:shp]
Gene
Sput200_3661  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
Sput200_2261  leucine dehydrogenase, Ldh [KO:K00263] [EC:1.4.1.9]
Sput200_2106  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) [KO:K00166] [EC:1.2.4.4]
Sput200_2105  3-methyl-2-oxobutanoate dehydrogenase complex, E1 component, beta subunit, BkdA2 [KO:K00167] [EC:1.2.4.4]
Sput200_2104  3-methyl-2-oxobutanoate dehydrogenase complex, E2 component, BkdB [KO:K09699] [EC:2.3.1.168]
Sput200_3553  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Sput200_1743  isovaleryl-CoA dehydrogenase, LiuA [KO:K00253] [EC:1.3.8.4]
Sput200_0013  fatty oxidation complex, alpha subunit FadB [KO:K01825] [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
Sput200_2483  fatty acid oxidation complex, alpha subunit FadJ [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
Sput200_2484  acetyl-CoA C-acyltransferase FadI [KO:K00632] [EC:2.3.1.16]
Sput200_0012  fatty oxidation complex, beta subunit, FadA [KO:K00632] [EC:2.3.1.16]
Sput200_1417  3-hydroxyisobutyrate dehydrogenase [KO:K00020] [EC:1.1.1.31]
Sput200_1413  methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.18 1.2.1.27]
Sput200_1084  methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.18 1.2.1.27]
Sput200_1085  aminotransferase class-III [KO:K00822] [EC:2.6.1.18]
Sput200_1105  GABA aminotransferase, PLP-dependent, PuuE [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
Sput200_1740  methylcrotonyl-CoA carboxylase, biotin-containing subunit, LiuD [KO:K01968] [EC:6.4.1.4]
Sput200_1742  methylcrotonyl-CoA carboxylase, carboxyl transferase subunit, LiuB [KO:K01969] [EC:6.4.1.4]
Sput200_1741  methylglutaconyl-CoA hydratase, LiuC [KO:K13766] [EC:4.2.1.18]
Sput200_1739  3-hydroxymethylglutaryl-CoA lyase, LiuE [KO:K01640] [EC:4.1.3.4]
Sput200_1738  acetyl-CoA:acetoacetate-CoA transferase, alpha subunit, AtoD [KO:K01028] [EC:2.8.3.5]
Sput200_1737  acetyl-CoA:acetoacetate-CoA transferase, beta subunit, AtoA [KO:K01029] [EC:2.8.3.5]
Sput200_1412  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
shp00020  Citrate cycle (TCA cycle)
shp00240  Pyrimidine metabolism
shp00290  Valine, leucine and isoleucine biosynthesis
shp00640  Propanoate metabolism
shp00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   
LinkDB

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