KEGG   PATHWAY: sjn00630
Entry
sjn00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces janthinus
Class
Metabolism; Carbohydrate metabolism
Pathway map
sjn00630  Glyoxylate and dicarboxylate metabolism
sjn00630

Module
sjn_M00621  Glycine cleavage system [PATH:sjn00630]
sjn_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sjn00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces janthinus [GN:sjn]
Gene
RI060_18780  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
RI060_08095  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
RI060_07915  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
RI060_15600  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
RI060_23915  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
RI060_27225  citrate synthase [KO:K01647] [EC:2.3.3.1]
RI060_10435  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
RI060_10440  citrate synthase [KO:K01647] [EC:2.3.3.1]
RI060_09730  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
RI060_12670  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RI060_17305  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RI060_25340  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RI060_29990  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
RI060_31895  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RI060_39940  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
RI060_40560  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
RI060_03550  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
RI060_05915  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
RI060_12675  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
RI060_07360  protein meaA [KO:K14447] [EC:5.4.99.63]
RI060_01885  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
RI060_15075  biotin carboxylase N-terminal domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
RI060_15050  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
RI060_15055  acyl-CoA carboxylase subunit epsilon [KO:K27095]
RI060_08135  methylmalonyl-CoA mutase family protein [KO:K01847] [EC:5.4.99.2]
RI060_08140  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
RI060_15335  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
RI060_26215  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
RI060_01770  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
RI060_39105  catalase [KO:K03781] [EC:1.11.1.6]
RI060_08050  catalase [KO:K03781] [EC:1.11.1.6]
RI060_03280  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
RI060_23625  haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
RI060_30575  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
RI060_30695  glnII; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
RI060_30905  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
RI060_34400  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
RI060_41955  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
RI060_05485  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
RI060_12845  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RI060_15500  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RI060_39040  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RI060_12220  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RI060_35675  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
RI060_12210  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
RI060_30995  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
RI060_08925  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
RI060_12215  gcvH; glycine cleavage system protein GcvH [KO:K02437]
RI060_08065  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
RI060_42065  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
RI060_08040  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
RI060_08045  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
RI060_31210  glycerate kinase [KO:K00865] [EC:2.7.1.165]
RI060_07390  glycerate kinase [KO:K00865] [EC:2.7.1.165]
RI060_30180  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RI060_39310  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RI060_10680  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RI060_13320  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
RI060_42680  NAD-dependent formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
RI060_34020  cytochrome b/b6 domain-containing protein [KO:K00127]
RI060_23980  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
RI060_39065  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sjn00010  Glycolysis / Gluconeogenesis
sjn00020  Citrate cycle (TCA cycle)
sjn00030  Pentose phosphate pathway
sjn00053  Ascorbate and aldarate metabolism
sjn00071  Fatty acid degradation
sjn00230  Purine metabolism
sjn00250  Alanine, aspartate and glutamate metabolism
sjn00260  Glycine, serine and threonine metabolism
sjn00620  Pyruvate metabolism
sjn00710  Carbon fixation by Calvin cycle
sjn00750  Vitamin B6 metabolism
sjn00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system