KEGG   PATHWAY: sld00630
Entry
sld00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces lydicus A02
Class
Metabolism; Carbohydrate metabolism
Pathway map
sld00630  Glyoxylate and dicarboxylate metabolism
sld00630

Module
sld_M00012  Glyoxylate cycle [PATH:sld00630]
sld_M00621  Glycine cleavage system [PATH:sld00630]
sld_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sld00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces lydicus A02 [GN:sld]
Gene
T261_7513  Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
T261_3798  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
T261_1323  hypothetical protein [KO:K01895] [EC:6.2.1.1]
T261_1839  Malate synthase [KO:K01638] [EC:2.3.3.9]
T261_3233  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
T261_5334  Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
T261_3326  Putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
T261_2052  Aconitate hydratase A [KO:K01681] [EC:4.2.1.3]
T261_5757  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
T261_5012  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
T261_7162  hypothetical protein [KO:K00626] [EC:2.3.1.9]
T261_0446  Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
T261_2671  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
T261_1242  Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
T261_2672  hypothetical protein [KO:K05606] [EC:5.1.99.1]
T261_1718  Protein MeaA [KO:K14447] [EC:5.4.99.63]
T261_4311  Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
T261_6485  Propionyl-CoA carboxylase beta chain [KO:K01966] [EC:6.4.1.3 2.1.3.15]
T261_6483  Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
T261_06729  Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
T261_3099  Propionyl-CoA carboxylase beta chain [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
T261_3100  hypothetical protein [KO:K27095]
T261_1277  Methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
T261_1278  Methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
T261_3160  Methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
T261_1325  hypothetical protein [KO:K19268] [EC:5.4.99.1]
T261_1326  hypothetical protein [KO:K01846] [EC:5.4.99.1]
T261_5190  Glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
T261_3003  Catalase [KO:K03781] [EC:1.11.1.6]
T261_1855  Catalase [KO:K03781] [EC:1.11.1.6]
T261_2837  Bromoperoxidase-catalase [KO:K03781] [EC:1.11.1.6]
T261_3377  hypothetical protein [KO:K01091] [EC:3.1.3.18]
T261_2065  hypothetical protein [KO:K01091] [EC:3.1.3.18]
T261_1148  hypothetical protein [KO:K01915] [EC:6.3.1.2]
T261_6636  hypothetical protein [KO:K01915] [EC:6.3.1.2]
T261_5916  putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
T261_5947  Glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
T261_5976  Glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
T261_2705  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
T261_3190  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
T261_2601  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
T261_7232  Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
T261_2599  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
T261_5994  hypothetical protein [KO:K00382] [EC:1.8.1.4]
T261_1991  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
T261_2600  Glycine cleavage system H protein [KO:K02437]
T261_0494  Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
T261_00530  Putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
T261_1853  Putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
T261_01960  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
T261_0492  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
T261_1724  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
T261_5705  hypothetical protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
T261_5792  KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
T261_1822  hypothetical protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
T261_2749  hypothetical protein [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
T261_6539  hypothetical protein [KO:K00127]
T261_3311  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
T261_1632  Formyl-CoA:oxalate CoA-transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sld00010  Glycolysis / Gluconeogenesis
sld00020  Citrate cycle (TCA cycle)
sld00030  Pentose phosphate pathway
sld00053  Ascorbate and aldarate metabolism
sld00071  Fatty acid degradation
sld00230  Purine metabolism
sld00250  Alanine, aspartate and glutamate metabolism
sld00260  Glycine, serine and threonine metabolism
sld00620  Pyruvate metabolism
sld00710  Carbon fixation by Calvin cycle
sld00750  Vitamin B6 metabolism
sld00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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