KEGG   PATHWAY: smar00330
Entry
smar00330                   Pathway                                
Name
Arginine and proline metabolism - Serratia marcescens SM39
Class
Metabolism; Amino acid metabolism
Pathway map
smar00330  Arginine and proline metabolism
smar00330

Module
smar_M00015  Proline biosynthesis, glutamate => proline [PATH:smar00330]
smar_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:smar00330]
smar_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:smar00330]
smar_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:smar00330]
smar_M00970  Proline degradation, proline => glutamate [PATH:smar00330]
Other DBs
GO: 0006525 0006560
Organism
Serratia marcescens SM39 [GN:smar]
Gene
SM39_4045  codA; cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
SM39_3566  speA; biosynthetic arginine decarboxylase, PLP-binding [KO:K01585] [EC:4.1.1.19]
SM39_3565  speB; agmatinase [KO:K01480] [EC:3.5.3.11]
SM39_1924  putative peptidyl-arginine deiminase [KO:K10536] [EC:3.5.3.12]
SM39_4793  speF; ornithine decarboxylase, inducible [KO:K01581] [EC:4.1.1.17]
SM39_3636  speC; ornithine decarboxylase, inducible [KO:K01581] [EC:4.1.1.17]
SM39_3599  speE; spermidine synthase [KO:K00797] [EC:2.5.1.16]
SM39_3600  speD; S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
SM39_3239  hypothetical protein [KO:K00316] [EC:1.5.99.6]
SM39_3240  aldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
SM39_3245  aldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
SM39_3138  speG; spermidine N1-acetyltransferase [KO:K00657] [EC:2.3.1.57]
SM39_1059  agmatinase [KO:K12255] [EC:3.5.3.7]
SM39_2325  astA; arginine succinyltransferase [KO:K00673] [EC:2.3.1.109]
SM39_2323  astB; succinylarginine dihydrolase [KO:K01484] [EC:3.5.3.23]
SM39_2326  astC; succinylornithine transaminase [KO:K00840] [EC:2.6.1.81]
SM39_2324  astD; succinylglutamic semialdehyde dehydrogenase [KO:K06447] [EC:1.2.1.71]
SM39_2322  astE; succinylglutamate desuccinylase [KO:K05526] [EC:3.5.1.96]
SM39_4908  putative glutamate-ammonia ligase [KO:K09470] [EC:6.3.1.11]
SM39_2780  gamma-glutamylputrescine synthetase 2 [KO:K09470] [EC:6.3.1.11]
SM39_1531  puuA; gamma-glutamylputrescine synthetase 1 [KO:K09470] [EC:6.3.1.11]
SM39_4944  tynA; putative tyramine oxidase [KO:K09471] [EC:1.4.3.-]
SM39_1527  puuB; gamma-glutamylputrescine oxidoreductase [KO:K09471] [EC:1.4.3.-]
SM39_1949  putative aldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
SM39_1528  puuC; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [KO:K09472] [EC:1.2.1.99]
SM39_1530  puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [KO:K09473] [EC:3.5.1.94]
SM39_3624  proC; pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
SM39_2388  putA; fused DNA-binding transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
SM39_0272  proB; gamma-glutamate kinase [KO:K00931] [EC:2.7.2.11]
SM39_0273  proA; gamma-glutamylphosphate reductase [KO:K00147] [EC:1.2.1.41]
SM39_1413  pip; proline iminopeptidase [KO:K01259] [EC:3.4.11.5]
SM39_1183  aspC; aspartate aminotransferase, PLP-dependent [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
smar00020  Citrate cycle (TCA cycle)
smar00220  Arginine biosynthesis
smar00250  Alanine, aspartate and glutamate metabolism
smar00260  Glycine, serine and threonine metabolism
smar00270  Cysteine and methionine metabolism
smar00310  Lysine degradation
smar00410  beta-Alanine metabolism
smar00470  D-Amino acid metabolism
smar00480  Glutathione metabolism
smar00630  Glyoxylate and dicarboxylate metabolism
smar00650  Butanoate metabolism
smar00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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