KEGG   PATHWAY: srim00630
Entry
srim00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces rimosus
Class
Metabolism; Carbohydrate metabolism
Pathway map
srim00630  Glyoxylate and dicarboxylate metabolism
srim00630

Module
srim_M00012  Glyoxylate cycle [PATH:srim00630]
srim_M00621  Glycine cleavage system [PATH:srim00630]
srim_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:srim00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces rimosus [GN:srim]
Gene
CP984_02305  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
CP984_07855  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
CP984_17730  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
CP984_02310  malate synthase A [KO:K01638] [EC:2.3.3.9]
CP984_07720  malate synthase A [KO:K01638] [EC:2.3.3.9]
CP984_15285  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
CP984_02320  bifunctional 2-methylcitrate synthase/citrate synthase [KO:K01647] [EC:2.3.3.1]
CP984_09940  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
CP984_09945  helix-turn-helix domain-containing protein [KO:K01647] [EC:2.3.3.1]
CP984_15740  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
CP984_26345  citrate synthase [KO:K01647] [EC:2.3.3.1]
CP984_08765  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
CP984_05945  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP984_06135  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP984_12355  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP984_24600  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP984_28550  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
CP984_35335  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
CP984_12360  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
CP984_07150  protein meaA [KO:K14447] [EC:5.4.99.63]
CP984_14645  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
CP984_14590  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
CP984_14595  acyl-CoA carboxylase subunit epsilon [KO:K27095]
CP984_06305  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CP984_06310  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CP984_25520  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
CP984_07810  catalase [KO:K03781] [EC:1.11.1.6]
CP984_12150  catalase [KO:K03781] [EC:1.11.1.6]
CP984_13375  catalase [KO:K03781] [EC:1.11.1.6]
CP984_14125  catalase [KO:K03781] [EC:1.11.1.6]
CP984_36155  catalase HPII [KO:K03781] [EC:1.11.1.6]
CP984_15980  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
CP984_08920  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
CP984_05435  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP984_29640  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP984_29875  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
CP984_33410  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP984_11845  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP984_12525  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP984_15095  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP984_35745  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
CP984_11835  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
CP984_08470  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CP984_29955  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CP984_11840  gcvH; glycine cleavage system protein GcvH [KO:K02437]
CP984_28725  gcvH; glycine cleavage system protein GcvH [KO:K02437]
CP984_37785  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
CP984_37790  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CP984_07795  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CP984_37795  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CP984_07800  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CP984_15580  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CP984_07180  glycerate kinase [KO:K00865] [EC:2.7.1.165]
CP984_39975  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
CP984_07655  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CP984_28815  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CP984_12840  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
CP984_36670  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
CP984_36675  4Fe-4S dicluster domain-containing protein [KO:K00124]
CP984_32880  formate dehydrogenase [KO:K00127]
CP984_15665  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
CP984_06595  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
srim00010  Glycolysis / Gluconeogenesis
srim00020  Citrate cycle (TCA cycle)
srim00030  Pentose phosphate pathway
srim00053  Ascorbate and aldarate metabolism
srim00071  Fatty acid degradation
srim00230  Purine metabolism
srim00250  Alanine, aspartate and glutamate metabolism
srim00260  Glycine, serine and threonine metabolism
srim00620  Pyruvate metabolism
srim00710  Carbon fixation by Calvin cycle
srim00750  Vitamin B6 metabolism
srim00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system