KEGG   PATHWAY: srim00230
Entry
srim00230                   Pathway                                
Name
Purine metabolism - Streptomyces rimosus
Class
Metabolism; Nucleotide metabolism
Pathway map
srim00230  Purine metabolism
srim00230

Module
srim_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:srim00230]
srim_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:srim00230]
srim_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:srim00230]
srim_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:srim00230]
srim_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:srim00230]
srim_M00546  Purine degradation, xanthine => urea [PATH:srim00230]
srim_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:srim00230]
srim_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:srim00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces rimosus [GN:srim]
Gene
CP984_11085  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
CP984_24370  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
CP984_21000  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CP984_20895  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CP984_15340  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CP984_20980  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
CP984_20970  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
CP984_20975  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
CP984_21005  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CP984_24805  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
CP984_24810  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
CP984_20920  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CP984_37135  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CP984_15335  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CP984_30695  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CP984_34100  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CP984_16420  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CP984_33795  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CP984_25865  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
CP984_14680  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
CP984_30500  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CP984_37685  nucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
CP984_17260  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CP984_22595  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
CP984_22605  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
CP984_27010  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CP984_25665  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CP984_02350  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
CP984_26715  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
CP984_02345  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
CP984_26720  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
CP984_02340  (2Fe-2S)-binding protein [KO:K13483]
CP984_26725  (2Fe-2S)-binding protein [KO:K13483]
CP984_37780  type 1 glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
CP984_15595  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
CP984_34385  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
CP984_18150  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
CP984_34285  guanylate kinase [KO:K00942] [EC:2.7.4.8]
CP984_10100  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
CP984_13280  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CP984_13285  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
CP984_17940  hypothetical protein [KO:K00526] [EC:1.17.4.1]
CP984_27835  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CP984_10160  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CP984_34105  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CP984_36520  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CP984_16950  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CP984_24515  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CP984_14580  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CP984_14350  CYTH domain-containing protein [KO:K05873] [EC:4.6.1.1]
CP984_04060  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CP984_20800  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CP984_30105  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
CP984_14775  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CP984_22115  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CP984_35300  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CP984_27810  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
CP984_30955  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
CP984_22345  adenylate kinase [KO:K00939] [EC:2.7.4.3]
CP984_34005  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
CP984_08240  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CP984_08250  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
CP984_08245  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
CP984_07770  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
CP984_07775  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
CP984_07780  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
CP984_14980  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
CP984_07700  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
CP984_26800  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
CP984_37320  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
CP984_37315  urease subunit beta [KO:K01429] [EC:3.5.1.5]
CP984_37310  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
srim00030  Pentose phosphate pathway
srim00220  Arginine biosynthesis
srim00250  Alanine, aspartate and glutamate metabolism
srim00260  Glycine, serine and threonine metabolism
srim00340  Histidine metabolism
srim00630  Glyoxylate and dicarboxylate metabolism
srim00730  Thiamine metabolism
srim00740  Riboflavin metabolism
srim00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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