KEGG   PATHWAY: sthm00630
Entry
sthm00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Caldimonas thermodepolymerans
Class
Metabolism; Carbohydrate metabolism
Pathway map
sthm00630  Glyoxylate and dicarboxylate metabolism
sthm00630

Module
sthm_M00012  Glyoxylate cycle [PATH:sthm00630]
sthm_M00621  Glycine cleavage system [PATH:sthm00630]
Other DBs
GO: 0046487 0043648
Organism
Caldimonas thermodepolymerans [GN:sthm]
Gene
IS481_08270  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
IS481_05420  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
IS481_11435  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
IS481_00645  malate synthase G [KO:K01638] [EC:2.3.3.9]
IS481_11855  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
IS481_11820  citrate synthase [KO:K01647] [EC:2.3.3.1]
IS481_11905  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
IS481_11890  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
IS481_00290  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
IS481_02725  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
IS481_02835  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
IS481_03145  thiolase family protein [KO:K00626] [EC:2.3.1.9]
IS481_03150  thiolase family protein [KO:K00626] [EC:2.3.1.9]
IS481_04425  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
IS481_08635  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
IS481_09230  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
IS481_10345  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
IS481_08640  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
IS481_16640  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
IS481_16645  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
IS481_16650  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
IS481_01735  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
IS481_07520  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
IS481_16140  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
IS481_04685  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
IS481_12735  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
IS481_11185  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
IS481_11175  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
IS481_07405  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
IS481_10005  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
IS481_11180  gcvH; glycine cleavage system protein GcvH [KO:K02437]
IS481_04000  glycine cleavage system protein H [KO:K02437]
IS481_06575  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
IS481_13295  glycerate kinase [KO:K11529] [EC:2.7.1.165]
IS481_07590  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
IS481_12685  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
IS481_17025  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
IS481_03950  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
IS481_13125  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
IS481_17020  NAD(P)H-dependent oxidoreductase subunit E [KO:K22515] [EC:1.17.1.9]
IS481_03955  fdxH; formate dehydrogenase subunit beta [KO:K00124]
IS481_13120  4Fe-4S dicluster domain-containing protein [KO:K00124]
IS481_03960  formate dehydrogenase subunit gamma [KO:K00127]
IS481_13110  formate dehydrogenase subunit gamma [KO:K00127]
IS481_00240  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
IS481_06580  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
IS481_06050  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
IS481_16995  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sthm00010  Glycolysis / Gluconeogenesis
sthm00020  Citrate cycle (TCA cycle)
sthm00030  Pentose phosphate pathway
sthm00053  Ascorbate and aldarate metabolism
sthm00071  Fatty acid degradation
sthm00230  Purine metabolism
sthm00250  Alanine, aspartate and glutamate metabolism
sthm00260  Glycine, serine and threonine metabolism
sthm00620  Pyruvate metabolism
sthm00710  Carbon fixation by Calvin cycle
sthm00750  Vitamin B6 metabolism
sthm00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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