KEGG   PATHWAY: stud00630
Entry
stud00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces tubercidicus
Class
Metabolism; Carbohydrate metabolism
Pathway map
stud00630  Glyoxylate and dicarboxylate metabolism
stud00630

Module
stud_M00621  Glycine cleavage system [PATH:stud00630]
stud_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:stud00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces tubercidicus [GN:stud]
Gene
STRTU_003174  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
STRTU_001353  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
STRTU_002683  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
STRTU_004624  citrate synthase [KO:K01647] [EC:2.3.3.1]
STRTU_001734  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
STRTU_001735  citrate synthase [KO:K01647] [EC:2.3.3.1]
STRTU_002752  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
STRTU_001565  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
STRTU_004305  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
STRTU_005016  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
STRTU_006259  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
STRTU_006618  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
STRTU_001060  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
STRTU_002151  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
STRTU_002152  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
STRTU_001168  protein meaA [KO:K14447] [EC:5.4.99.63]
STRTU_000263  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
STRTU_002549  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
STRTU_002541  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
STRTU_002542  acyl-CoA carboxylase subunit epsilon [KO:K27095]
STRTU_001090  methylmalonyl-CoA mutase subunit beta [KO:K01847] [EC:5.4.99.2]
STRTU_001091  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
STRTU_002620  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
STRTU_004461  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
STRTU_001371  catalase [KO:K03781] [EC:1.11.1.6]
STRTU_002307  catalase [KO:K03781] [EC:1.11.1.6]
STRTU_002444  catalase [KO:K03781] [EC:1.11.1.6]
STRTU_001577  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
STRTU_002813  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
STRTU_005153  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
STRTU_005184  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
STRTU_005207  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
STRTU_005814  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
STRTU_000971  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
STRTU_001356  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
STRTU_002083  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
STRTU_002185  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
STRTU_002642  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
STRTU_006324  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
STRTU_002081  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
STRTU_005223  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
STRTU_001516  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
STRTU_002082  gcvH; glycine cleavage system protein GcvH [KO:K02437]
STRTU_000353  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
STRTU_001369  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
STRTU_000352  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
STRTU_001370  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
STRTU_001174  glycerate kinase [KO:K00865] [EC:2.7.1.165]
STRTU_004975  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
STRTU_005050  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
STRTU_001339  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
STRTU_002231  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
STRTU_000837  NAD-dependent formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
STRTU_005723  cytochrome b/b6 domain-containing protein [KO:K00127]
STRTU_002738  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
STRTU_000522  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
stud00010  Glycolysis / Gluconeogenesis
stud00020  Citrate cycle (TCA cycle)
stud00030  Pentose phosphate pathway
stud00053  Ascorbate and aldarate metabolism
stud00071  Fatty acid degradation
stud00230  Purine metabolism
stud00250  Alanine, aspartate and glutamate metabolism
stud00260  Glycine, serine and threonine metabolism
stud00620  Pyruvate metabolism
stud00710  Carbon fixation by Calvin cycle
stud00750  Vitamin B6 metabolism
stud00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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