KEGG   PATHWAY: tfu00230
Entry
tfu00230                    Pathway                                
Name
Purine metabolism - Thermobifida fusca
Class
Metabolism; Nucleotide metabolism
Pathway map
tfu00230  Purine metabolism
tfu00230

Module
tfu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:tfu00230]
tfu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:tfu00230]
tfu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tfu00230]
tfu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tfu00230]
tfu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tfu00230]
Other DBs
GO: 0006163 0042278
Organism
Thermobifida fusca [GN:tfu]
Gene
Tfu_0415  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Tfu_2747  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Tfu_3013  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Tfu_2573  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Tfu_0158  phosphoribosylformylglycinamidine synthase subunit II [KO:K23269] [EC:6.3.5.3]
Tfu_0178  phosphoribosylformylglycinamidine synthetase PurS [KO:K23264] [EC:6.3.5.3]
Tfu_0156  phosphoribosylformylglycinamidine synthase subunit I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Tfu_2748  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Tfu_2547  phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
Tfu_2546  1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase [KO:K01588] [EC:5.4.99.18]
Tfu_3015  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Tfu_3014  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Tfu_2572  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Tfu_2091  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Tfu_1760  HAD-superfamily hydrolase, subfamily IIA [KO:K02566] [EC:3.1.3.5]
Tfu_2242  inosine guanosine and xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
Tfu_1114  Protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Tfu_2896  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Tfu_2595  IMP dehydrogenase related 2 [KO:K00088] [EC:1.1.1.205]
Tfu_2596  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Tfu_2188  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Tfu_2364  Ham1-like protein [KO:K01519] [EC:3.6.1.66]
Tfu_2589  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
Tfu_2440  IMP dehydrogenase related 1 [KO:K26110] [EC:1.7.1.7]
Tfu_1062  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Tfu_2149  ribonucleotide reductase large subunit [KO:K00525] [EC:1.17.4.1]
Tfu_3001  ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
Tfu_3002  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
Tfu_0865  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Tfu_2090  RelA/SpoT protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Tfu_0431  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Tfu_2552  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Tfu_3012  Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Tfu_1012  putative carbohydrate kinase [KO:K00856] [EC:2.7.1.20]
Tfu_2563  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Tfu_2662  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Tfu_2625  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Tfu_2105  conserved hypothetical protein [KO:K19710] [EC:2.7.7.53]
Tfu_0420  sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
Tfu_0419  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Tfu_0425  adenylylsulfate kinase [KO:K00958] [EC:2.7.7.4]
Tfu_0962  dihydroorotase [KO:K01466] [EC:3.5.2.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
tfu00030  Pentose phosphate pathway
tfu00220  Arginine biosynthesis
tfu00250  Alanine, aspartate and glutamate metabolism
tfu00260  Glycine, serine and threonine metabolism
tfu00340  Histidine metabolism
tfu00630  Glyoxylate and dicarboxylate metabolism
tfu00730  Thiamine metabolism
tfu00740  Riboflavin metabolism
tfu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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