KEGG   PATHWAY: tgr00230
Entry
tgr00230                    Pathway                                
Name
Purine metabolism - Thioalkalivibrio sulfidiphilus
Class
Metabolism; Nucleotide metabolism
Pathway map
tgr00230  Purine metabolism
tgr00230

Module
tgr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:tgr00230]
tgr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:tgr00230]
tgr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tgr00230]
tgr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tgr00230]
tgr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tgr00230]
Other DBs
GO: 0006163 0042278
Organism
Thioalkalivibrio sulfidiphilus [GN:tgr]
Gene
Tgr7_1377  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Tgr7_2931  NUDIX hydrolase [KO:K08312] [EC:3.6.1.-]
Tgr7_1484  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
Tgr7_0527  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Tgr7_1259  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Tgr7_0360  Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Tgr7_2254  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Tgr7_3291  Phosphoribosylaminoimidazole carboxylase [KO:K08289] [EC:6.3.1.21]
Tgr7_1501  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
Tgr7_2253  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Tgr7_2884  Phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
Tgr7_2885  Phosphoribosylaminoimidazole carboxylase [KO:K01588] [EC:5.4.99.18]
Tgr7_2886  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Tgr7_1849  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Tgr7_0361  IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Tgr7_2431  5'-nucleotidase precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Tgr7_1432  stationary-phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Tgr7_2930  putative hydrolase [KO:K20881] [EC:3.1.3.-]
Tgr7_0015  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
Tgr7_0816  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Tgr7_1752  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Tgr7_1035  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Tgr7_2052  Nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Tgr7_2961  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Tgr7_1036  GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
Tgr7_3187  Guanylate kinase [KO:K00942] [EC:2.7.4.8]
Tgr7_2615  Ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
Tgr7_2673  Ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
Tgr7_2614  Ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
Tgr7_3031  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Tgr7_3185  GTP diphosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Tgr7_2467  Guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Tgr7_2113  GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
Tgr7_1910  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Tgr7_0672  conserved hypothetical protein [KO:K01768] [EC:4.6.1.1]
Tgr7_0506  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Tgr7_0903  Adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
Tgr7_0173  PfkB domain protein [KO:K00856] [EC:2.7.1.20]
Tgr7_2713  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Tgr7_0354  Nucleoside-triphosphate--adenylate kinase [KO:K00939] [EC:2.7.4.3]
Tgr7_2504  MazG protein [KO:K04765] [EC:3.6.1.9]
Tgr7_0570  Icc protein [KO:K03651] [EC:3.1.4.53]
Tgr7_2728  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
Tgr7_0353  Sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
Tgr7_3104  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Tgr7_3103  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
Tgr7_3102  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
tgr00030  Pentose phosphate pathway
tgr00220  Arginine biosynthesis
tgr00250  Alanine, aspartate and glutamate metabolism
tgr00260  Glycine, serine and threonine metabolism
tgr00340  Histidine metabolism
tgr00630  Glyoxylate and dicarboxylate metabolism
tgr00730  Thiamine metabolism
tgr00740  Riboflavin metabolism
tgr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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