KEGG   PATHWAY: xau00630
Entry
xau00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Xanthobacter autotrophicus
Class
Metabolism; Carbohydrate metabolism
Pathway map
xau00630  Glyoxylate and dicarboxylate metabolism
xau00630

Module
xau_M00621  Glycine cleavage system [PATH:xau00630]
xau_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:xau00630]
Other DBs
GO: 0046487 0043648
Organism
Xanthobacter autotrophicus [GN:xau]
Gene
Xaut_1479  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Xaut_3527  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Xaut_2096  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Xaut_1859  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Xaut_4252  malate synthase G [KO:K01638] [EC:2.3.3.9]
Xaut_1673  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Xaut_0153  malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
Xaut_0258  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Xaut_2669  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Xaut_4425  citrate synthase I [KO:K01647] [EC:2.3.3.1]
Xaut_3852  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
Xaut_1384  Thiolase [KO:K00626] [EC:2.3.1.9]
Xaut_1335  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Xaut_4665  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Xaut_2007  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Xaut_3108  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Xaut_3107  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Xaut_2482  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
Xaut_1195  crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
Xaut_4617  Methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Xaut_1197  methylmalonyl-CoA mutase, large subunit [KO:K14447] [EC:5.4.99.63]
Xaut_0310  acyl-CoA dehydrogenase domain protein [KO:K14448] [EC:1.3.8.12]
Xaut_1970  MaoC domain protein dehydratase [KO:K14449] [EC:4.2.1.148]
Xaut_3870  HpcH/HpaI aldolase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
Xaut_4726  Carbamoyl-phosphate synthase L chain ATP-binding [KO:K01965] [EC:6.4.1.3]
Xaut_4725  carboxyl transferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Xaut_4731  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
Xaut_4729  Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Xaut_1870  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Xaut_1869  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Xaut_1868  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Xaut_2321  Catalase [KO:K03781] [EC:1.11.1.6]
Xaut_4126  Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
Xaut_2571  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Xaut_1534  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00018] [EC:1.1.1.29]
Xaut_4762  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
Xaut_3219  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Xaut_2473  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Xaut_1918  Ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
Xaut_1917  Ribulose-bisphosphate carboxylase [KO:K01602] [EC:4.1.1.39]
Xaut_3585  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Xaut_1141  Glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
Xaut_0887  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Xaut_1939  Glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
Xaut_2336  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Xaut_0870  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Xaut_4276  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Xaut_2198  Glycine dehydrogenase (decarboxylating) [KO:K00282] [EC:1.4.4.2]
Xaut_2197  Glycine dehydrogenase (decarboxylating) [KO:K00283] [EC:1.4.4.2]
Xaut_3184  glycine cleavage T protein (aminomethyl transferase) [KO:K00605] [EC:2.1.2.10]
Xaut_3187  glycine cleavage T protein (aminomethyl transferase) [KO:K00605] [EC:2.1.2.10]
Xaut_2201  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Xaut_0923  glycine cleavage T protein (aminomethyl transferase) [KO:K00605] [EC:2.1.2.10]
Xaut_0159  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Xaut_3894  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Xaut_2200  glycine cleavage system H protein [KO:K02437]
Xaut_2367  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
Xaut_2368  Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Xaut_2369  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Xaut_2433  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Xaut_3104  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
Xaut_1019  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Xaut_3477  putative NAD-dependent formate dehydrogenase delta subunit protein [KO:K00126] [EC:1.17.1.9]
Xaut_3479  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Xaut_0662  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Xaut_0663  molybdopterin oxidoreductase Fe4S4 region [KO:K00123] [EC:1.17.1.9]
Xaut_0661  formate dehydrogenase, beta subunit [KO:K00124]
Xaut_3480  NADH dehydrogenase (quinone) [KO:K00124]
Xaut_3481  NADH dehydrogenase (ubiquinone) 24 kDa subunit [KO:K00127]
Xaut_0660  formate dehydrogenase, gamma subunit [KO:K00127]
Xaut_0649  esterase/lipase-like protein [KO:K01432] [EC:3.5.1.9]
Xaut_4704  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Xaut_0486  thiamine pyrophosphate protein TPP binding domain protein [KO:K01577] [EC:4.1.1.8]
Xaut_0489  L-carnitine dehydratase/bile acid-inducible protein F [KO:K07749] [EC:2.8.3.16]
Xaut_0487  L-carnitine dehydratase/bile acid-inducible protein F [KO:K07749] [EC:2.8.3.16]
Xaut_1246  L-carnitine dehydratase/bile acid-inducible protein F [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
xau00010  Glycolysis / Gluconeogenesis
xau00020  Citrate cycle (TCA cycle)
xau00030  Pentose phosphate pathway
xau00053  Ascorbate and aldarate metabolism
xau00071  Fatty acid degradation
xau00230  Purine metabolism
xau00250  Alanine, aspartate and glutamate metabolism
xau00260  Glycine, serine and threonine metabolism
xau00620  Pyruvate metabolism
xau00710  Carbon fixation by Calvin cycle
xau00750  Vitamin B6 metabolism
xau00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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