Entry
Name
ABC transporters - Yersinia hibernica LC20
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Yersinia hibernica LC20 [GN:
yel ]
Gene
LC20_04537 thiP; thiamine/thiamine pyrophosphate ABC transporter permease ThiP [KO:K02063 ]
LC20_03539 spermidine/putrescine ABC transporter substrate-binding protein PotF [KO:K11073 ]
LC20_04243 proline/glycine betaine ABC transporter substrate-binding protein ProX [KO:K02002 ]
LC20_00440 maltose/maltodextrin ABC transporter substrate-binding protein MalE [KO:K10108 ]
LC20_00441 maltose/maltodextrin ABC transporter ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
LC20_00655 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
LC20_01924 galactose/glucose ABC transporter substrate-binding protein MglB [KO:K10540 ]
LC20_01927 galactose/methyl galactoside ABC transporter permease MglC [KO:K10541 ]
LC20_04994 sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB [KO:K05813 ]
LC20_01843 phnD; phosphonate ABC transporter substrate-binding protein [KO:K02044 ]
LC20_01620 glutamate/aspartate ABC transporter substrate-binding protein [KO:K10001 ]
LC20_05009 branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
LC20_05008 high-affinity branched-chain amino acid ABC transporter permease LivH [KO:K01997 ]
LC20_05007 livM; high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998 ]
LC20_05005 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF [KO:K01996 ]
LC20_07670 oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
LC20_02549 oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
LC20_02842 oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
LC20_02553 oppD; oligopeptide ABC transporter ATP-binding protein OppD [KO:K15583 ]
LC20_00738 Fe2+-enterobactin ABC transporter substrate-binding protein [KO:K23185 ]
LC20_04423 vitamin B12 ABC transporter substrate-binding protein BtuF [KO:K06858 ]
LC20_02046 energy-coupling factor ABC transporter substrate-binding protein [KO:K02009 ]
LC20_07365 energy-coupling factor ABC transporter transmembrane protein [KO:K02008 ]
LC20_02049 energy-coupling factor ABC transporter ATP-binding protein [KO:K02006 ]
LC20_04668 autoinducer 2 ABC transporter substrate-binding protein LsrB [KO:K10555 ]
LC20_03321 lipoprotein-releasing system ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
LC20_03497 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC [KO:K16012 ]
LC20_03495 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD [KO:K16013 ]
LC20_03504 macrolide ABC transporter ATP-binding protein/permease MacB [KO:K05685 ] [EC:7.6.2.-]
LC20_04367 macrolide ABC transporter permease/ATP-binding protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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