KEGG   PATHWAY: psom00760
Entry
psom00760                   Pathway                                
Name
Nicotinate and nicotinamide metabolism - Papaver somniferum (opium poppy)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
psom00760  Nicotinate and nicotinamide metabolism
psom00760

Module
psom_M00115  NAD biosynthesis, aspartate => quinolinate => NAD [PATH:psom00760]
Other DBs
UMBBD: nic
GO: 0046497 0006769
Organism
Papaver somniferum (opium poppy) [GN:psom]
Gene
113300045  L-aspartate oxidase, chloroplastic-like [KO:K00278] [EC:1.4.3.16]
113318236  L-aspartate oxidase, chloroplastic-like [KO:K00278] [EC:1.4.3.16]
113299495  quinolinate synthase, chloroplastic-like [KO:K03517] [EC:2.5.1.72]
113341984  quinolinate synthase, chloroplastic-like [KO:K03517] [EC:2.5.1.72]
113310050  nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic-like [KO:K00767] [EC:2.4.2.19]
113320837  nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic-like isoform X1 [KO:K00767] [EC:2.4.2.19]
113289534  nicotinate phosphoribosyltransferase 2-like [KO:K00763] [EC:6.3.4.21]
113297985  nicotinate phosphoribosyltransferase 2-like [KO:K00763] [EC:6.3.4.21]
113320210  7-methylguanosine phosphate-specific 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
113333299  uncharacterized protein LOC113333299 isoform X1 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
113318309  uncharacterized protein LOC113318309 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
113295615  uncharacterized protein LOC113295615 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
113347083  uncharacterized protein LOC113347083 [KO:K18551] [EC:3.1.3.-]
113332629  uncharacterized protein LOC113332629 [KO:K18551] [EC:3.1.3.-]
113319804  probable uridine nucleosidase 2 [KO:K01240] [EC:3.2.2.3]
113321759  uridine nucleosidase 1-like [KO:K01240] [EC:3.2.2.3]
113314130  uridine nucleosidase 1-like [KO:K01240] [EC:3.2.2.3]
113329432  probable uridine nucleosidase 2 [KO:K01240] [EC:3.2.2.3]
113294681  nicotinamide/nicotinic acid mononucleotide adenylyltransferase-like isoform X1 [KO:K06210] [EC:2.7.7.1 2.7.7.18]
113319177  nicotinamide/nicotinic acid mononucleotide adenylyltransferase-like [KO:K06210] [EC:2.7.7.1 2.7.7.18]
113358924  nicotinamide/nicotinic acid mononucleotide adenylyltransferase-like [KO:K06210] [EC:2.7.7.1 2.7.7.18]
113295221  ectonucleotide pyrophosphatase/phosphodiesterase family member 3-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
113340999  nudix hydrolase 19, chloroplastic-like isoform X1 [KO:K03426] [EC:3.6.1.22]
113355709  nudix hydrolase 19, chloroplastic-like [KO:K03426] [EC:3.6.1.22]
113311066  nudix hydrolase 10-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
113298536  nudix hydrolase 10-like isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
113302071  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
113288180  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
113307724  glutamine-dependent NAD(+) synthetase-like [KO:K01950] [EC:6.3.5.1]
113283605  glutamine-dependent NAD(+) synthetase-like isoform X1 [KO:K01950] [EC:6.3.5.1]
113351661  glutamine-dependent NAD(+) synthetase-like [KO:K01950] [EC:6.3.5.1]
113356798  glutamine-dependent NAD(+) synthetase-like [KO:K01950] [EC:6.3.5.1]
113287381  NAD-dependent protein deacylase SRT2-like isoform X1 [KO:K11414] [EC:2.3.1.286 2.3.1.313]
113309367  NAD-dependent protein deacylase SRT2-like isoform X1 [KO:K11414] [EC:2.3.1.286 2.3.1.313]
113288177  NAD-dependent protein deacetylase SRT1-like [KO:K11416] [EC:2.3.1.286]
113302054  NAD-dependent protein deacetylase SRT1-like [KO:K11416] [EC:2.3.1.286]
113322403  probable NAD kinase 1 [KO:K00858] [EC:2.7.1.23]
113346309  NAD kinase 2, chloroplastic-like isoform X1 [KO:K00858] [EC:2.7.1.23]
113287469  NADH kinase-like isoform X1 [KO:K00858] [EC:2.7.1.23]
113309706  NADH kinase-like isoform X1 [KO:K00858] [EC:2.7.1.23]
113309489  probable NAD kinase 1 isoform X1 [KO:K00858] [EC:2.7.1.23]
113356426  NAD kinase 2, chloroplastic-like isoform X1 [KO:K00858] [EC:2.7.1.23]
Compound
C00003  NAD+
C00006  NADP+
C00022  Pyruvate
C00042  Succinate
C00049  L-Aspartate
C00111  Glycerone phosphate
C00122  Fumarate
C00153  Nicotinamide
C00163  Propanoate
C00232  Succinate semialdehyde
C00253  Nicotinate
C00334  4-Aminobutanoate
C00455  Nicotinamide D-ribonucleotide
C00745  Nicotine
C00857  Deamino-NAD+
C00922  2,3-Dimethylmaleate
C01020  6-Hydroxynicotinate
C01056  (S)-6-Hydroxynicotine
C01059  2,5-Dihydroxypyridine
C01185  Nicotinate D-ribonucleotide
C01297  6-Hydroxypseudooxynicotine
C01384  Maleic acid
C01596  Maleamate
C02295  Methylitaconate
C02918  1-Methylnicotinamide
C02930  2-Methyleneglutarate
C03043  (R)-6-Hydroxynicotine
C03056  2,6-Dihydroxypyridine
C03150  Nicotinamide-beta-riboside
C03458  2,3,6-Trihydroxypyridine
C03652  (2R,3S)-2,3-Dimethylmalate
C03722  Quinolinate
C04226  6-Oxo-1,4,5,6-tetrahydronicotinate
C05380  Nicotinurate
C05840  Iminoaspartate
C05841  Nicotinate D-ribonucleoside
C05842  N1-Methyl-2-pyridone-5-carboxamide
C05843  N1-Methyl-4-pyridone-5-carboxamide
C06178  1-Methylpyrrolinium
C15523  2,6-Dihydroxynicotinate
C15986  2,6-Dihydroxypseudooxynicotine
C15987  4-Methylaminobutyrate
C16151  2,6-Dihydroxy-N-methylmyosmine
C16152  Blue pigment
C16159  2-Formylglutarate
C16386  (R)-Nicotine
C16390  (S)-2-(Hydroxymethyl)glutarate
C18232  N-Formylmaleamic acid
C19567  4-Oxo-1-(3-pyridyl)-1-butanone
C19569  3-Succinoylpyridine
C19631  6-Hydroxy-3-succinoylpyridine
C20361  Pseudooxynicotine
C20381  3,3'-Bipyridine-2,2',5,5',6,6'-hexol
C21075  5-(N-Methyl-4,5-dihydro-1H-pyrrol-2-yl)pyridin-2-ol
C21154  N-Methylmyosmine
Reference
PMID:13475371
  Authors
BEHRMAN EJ, STANIER RY.
  Title
The bacterial oxidation of nicotinic acid.
  Journal
J Biol Chem 228:923-45 (1957)
Reference
PMID:16894175
  Authors
Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ.
  Title
Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri.
  Journal
Proc Natl Acad Sci U S A 103:12341-6 (2006)
DOI:10.1073/pnas.0601635103
Reference
PMID:11514508
  Authors
Baitsch D, Sandu C, Brandsch R, Igloi GL.
  Title
Gene cluster on pAO1 of Arthrobacter nicotinovorans involved in degradation of the plant alkaloid nicotine: cloning, purification, and characterization of 2,6-dihydroxypyridine 3-hydroxylase.
  Journal
J Bacteriol 183:5262-7 (2001)
DOI:10.1128/JB.183.18.5262-5267.2001
Reference
PMID:16321959
  Authors
Sachelaru P, Schiltz E, Igloi GL, Brandsch R.
  Title
An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans.
  Journal
J Bacteriol 187:8516-9 (2005)
DOI:10.1128/JB.187.24.8516-8519.2005
Reference
PMID:5835946
  Authors
Gherna RL, Richardson SH, Rittenberg SC
  Title
The bacterial oxidation of nicotine. VI. The metabolism of 2,6-dihydroxypseudooxynicotine.
  Journal
J Biol Chem 240:3669-74 (1965)
Reference
PMID:21953451
  Authors
Galeazzi L, Bocci P, Amici A, Brunetti L, Ruggieri S, Romine M, Reed S, Osterman AL, Rodionov DA, Sorci L, Raffaelli N
  Title
Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family.
  Journal
J Biol Chem 286:40365-75 (2011)
DOI:10.1074/jbc.M111.275818
Related
pathway
psom00020  Citrate cycle (TCA cycle)
psom00250  Alanine, aspartate and glutamate metabolism
psom00380  Tryptophan metabolism
psom00620  Pyruvate metabolism
psom00660  C5-Branched dibasic acid metabolism
psom00960  Tropane, piperidine and pyridine alkaloid biosynthesis
KO pathway
ko00760   
LinkDB

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