KEGG   PATHWAY: scb00630
Entry
scb00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces scabiei
Class
Metabolism; Carbohydrate metabolism
Pathway map
scb00630  Glyoxylate and dicarboxylate metabolism
scb00630

Module
scb_M00621  Glycine cleavage system [PATH:scb00630]
scb_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:scb00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces scabiei [GN:scb]
Gene
SCAB_41241  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SCAB_18631  putative acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SCAB_18361  aceB1; malate synthase [KO:K01638] [EC:2.3.3.9]
SCAB_35681  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SCAB_51341  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
SCAB_58791  citA; citrate synthase [KO:K01647] [EC:2.3.3.1]
SCAB_21101  sacA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
SCAB_54571  fadA2; putative acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
SCAB_84931  ltp3; PROBABLE LIPID CARRIER PROTEIN OR KETO ACYL-COA THIOLASE LTP3 [KO:K00626] [EC:2.3.1.9]
SCAB_68691  putative thiolase [KO:K00626] [EC:2.3.1.9]
SCAB_13361  fadA4; putative thiolase/acety-coA transferase [KO:K00626] [EC:2.3.1.9]
SCAB_65321  putative acetyl-coA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SCAB_28481  fadA; putative acetyl-coA C-acetyltransferase FadA [KO:K00626] [EC:2.3.1.9]
SCAB_28491  conserved hypothetical protein [KO:K05606] [EC:5.1.99.1]
SCAB_17631  coenzyme B12-dependent mutase [KO:K14447] [EC:5.4.99.63]
SCAB_78981  pccB; putative propionyl-CoA carboxylase complex B subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
SCAB_34621  accA2; putative acyl-CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SCAB_34571  pccB; propionyl-CoA carboxylase complex B subunit [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
SCAB_34581  conserved hypothetical protein [KO:K27095]
SCAB_23031  mutA; putative methylmalonyl-CoA mutase small subunit MutA (MCM) [KO:K01847] [EC:5.4.99.2]
SCAB_23041  mutB; putative Methylmalonyl-CoA mutase large subunit MutB (MCM) [KO:K01847] [EC:5.4.99.2]
SCAB_35151  mutA2; methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
SCAB_56391  putative oxidoreductase [KO:K00104] [EC:1.1.99.14]
SCAB_17231  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
SCAB_50801  conserved hypothetical protein [KO:K01091] [EC:3.1.3.18]
SCAB_21531  putative hydrolase [KO:K01091] [EC:3.1.3.18]
SCAB_9661  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SCAB_66491  putative glutamine synthetase (EC 6.3.1.2) [KO:K01915] [EC:6.3.1.2]
SCAB_66791  glnII; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SCAB_66881  glnA; glutamine synthetase I [KO:K01915] [EC:6.3.1.2]
SCAB_73851  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SCAB_21581  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SCAB_6851  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SCAB_35641  glyA1; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SCAB_28851  glyA3; putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SCAB_27491  glyA2; putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SCAB_76331  putative glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
SCAB_27461  gcvT; putative glycine cleavage T protein aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
SCAB_67061  putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SCAB_27481  gcvH; putative glycine cleavage H protein [KO:K02437]
SCAB_18601  putative glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
SCAB_18571  putative oxidoreductase [KO:K01816] [EC:5.3.1.22]
SCAB_18581  putative dehydrogenase [KO:K00042] [EC:1.1.1.60]
SCAB_17701  putative transferase [KO:K00865] [EC:2.7.1.165]
SCAB_6561  kgdA; putative KHG/KDPG aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase] [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SCAB_87531  putative aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SCAB_65671  kdgA; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SCAB_29781  putative 2-oxoglutarate dehydrogenase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
SCAB_72931  putative membrane protein [KO:K00127]
SCAB_15251  putative esterase [KO:K01432] [EC:3.5.1.9]
SCAB_7011  putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SCAB_51501  putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
scb00010  Glycolysis / Gluconeogenesis
scb00020  Citrate cycle (TCA cycle)
scb00030  Pentose phosphate pathway
scb00053  Ascorbate and aldarate metabolism
scb00071  Fatty acid degradation
scb00230  Purine metabolism
scb00250  Alanine, aspartate and glutamate metabolism
scb00260  Glycine, serine and threonine metabolism
scb00620  Pyruvate metabolism
scb00710  Carbon fixation by Calvin cycle
scb00750  Vitamin B6 metabolism
scb00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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